Abstract: A method for identifying deleterious genetic mutations, which method relates to the technical field of biomolecules. The method comprises: respectively converting, into density maps, obtained Ramachandran plots of wild-type proteins, benign protein variants, pathogenic protein variants, and proteins to be identified; dividing each density map into a plurality of regions, and by using the density maps of the benign protein variants, the pathogenic protein variants and the wild-type proteins as a reference, calculating an average density and a standard deviation of each region; if the deviation between the density of the proteins to be identified in each region and the average density of the region exceeds the standard deviation, marking the region as a density deviation region of the proteins to be identified; and on the basis of deviation data of the density deviation region of the proteins to be identified, determining mutations of the proteins to be identified.

Abstract: Systems and methods are provided for synchronizing messages. The systems and methods include operations for: identifying a difference between a current state of a messaging application and a shared synchronization database, wherein the shared synchronization database is updated via a third-party application in response to the third-party application receiving, from a server, a notification related to the messaging application, the messaging application and the third-party application being implemented on a client device; retrieving information from the shared synchronization database to update the current state of the messaging application based on the identified difference; and transmitting, to the server by the messaging application, a request for content based on the update to the current state of the messaging application.

Abstract: The present technology is directed to real-time screening, validating, and tracking infectious diseases including Coronavirus (COVID-19) and the like at port of entry including airports, seaports, ferries, and any international border controls.

Abstract: A complete fuel cell system (10) is disclosed. The fuel cell system (10) comprises at least two fuel precursors (16, 18) that react to create hydrogen. A solid fuel precursor (18) can be carried in disposable fuel cartridges (100). A passive pressure control system including a dose pump (22) and a pressure equalization system (24, 300, 504) is provided to dose a liquid fuel precursor (16) to the solid fuel precursor (18) in the fuel cartridge (100). The solid fuel precursor (18) may include larger metallic particles coated by another fine metallic particles such that multiple micro galvanic cells are formed on the surface of the larger metallic particles. The fuel cell system (10) may also include a gas buffer (40) that stores produced hydrogen that is unneeded by the fuel cell, a water trapping mechanism (604) and an electronic vent (46) that consumes unneeded hydrogen.

Abstract: Purge valves (I 09, I 09?, 200) that are manually turned ON but are automatically or electrically turned OFF as the fuel cell (108)'s production of electricity reaches a predetermined level, e.g., steady state or thereabout are disclosed. The purge valve may be opened at system start-up, or may be opened at system shut-down so that the purge valve is anned and the fuel cell system is purged at the next start-up. Also disclosed is an integrated fluidic interface module (10) that contains various fluidic components including one of these purge valves. The integrated fluidic interface module (10) can operate passively or without being actively controlled by a processor. Methods of operating a fuel cell system, wherein the fuel cell system is purged at system start-up, are also disclosed. The purging automatically stops when the anode plenum is fully purged and replaced with fuel.

Abstract: Purge valves that are manually turned ON but are automatically or electrically turned OFF as the fuel cell's production of electricity reaches a predetermined level, e.g., steady state or thereabout are disclosed. The purge valve may be opened at system start-up, or may be opened at system shut-down so that the purge valve is armed and the fuel cell system is purged at the next start-up. Also disclosed is an integrated fluidic interface module that contains various fluidic components including one of these purge valves. The integrated fluidic interface module can operate passively or without being actively controlled by a processor. Methods of operating a fuel cell system, wherein the fuel cell system is purged at system start-up, are also disclosed. The purging automatically stops when the anode plenum is fully purged and replaced with fuel.

Abstract: Purge valves (I 09, I 09?, 200) that are manually turned ON but are automatically or electrically turned OFF as the fuel cell (108)'s production of electricity reaches a predetermined level, e.g., steady state or thereabout are disclosed. The purge valve may be opened at system start-up, or may be opened at system shut-down so that the purge valve is anned and the fuel cell system is purged at the next start-up. Also disclosed is an integrated fluidic interface module (10) that contains various fluidic components including one of these purge valves. The integrated fluidic interface module (10) can operate passively or without being actively controlled by a processor. Methods of operating a fuel cell system, wherein the fuel cell system is purged at system start-up, are also disclosed. The purging automatically stops when the anode plenum is fully purged and replaced with fuel.

Abstract: A complete fuel cell system (10) is described. The fuel cell system (10) comprises at least two fuel precursors (16, 18) that react to create hydrogen. A solid fuel precursor (18) can be carried in disposable fuel cartridges (100). A passive pressure control system including a dose pump (22) and a pressure equalization system (24, 300, 504) is provided to dose a liquid fuel precursor (16) to the solid fuel precursor (18) in the fuel cartridge (100). An outer wall (102) of the fuel cartridge can form a part of the passive pressure control system. The solid fuel precursor may include larger metallic particles coated by another fine metallic particles such that multiple micro galvanic cells are formed on the surface of the larger metallic particles. The fuel cell system may also include a gas buffer (40) that stores produced hydrogen that in unneeded by the fuel cell, and a water trapping mechanism (604). The fuel cell system may also have an electronic vent (46) that consumes unneeded hydrogen.

Abstract: Methods, articles, and systems for controlling the internal operating temperature of fuel cell systems, such as planar fuel cell arrays. The heat management system conducts heat away from the fuel cell without disturbing the flow of gases around the fuel cell layer and without the need for the equipment to disturb the flow of gases around the fuel cell layer. The present invention also provides a heat transfer system that has a low thermal mass relative to the fuel cell layer or is thermally isolated from the fuel cell layer such that the heat transfer system will not remove substantial amounts of heat from a fuel cell layer during star-up and can be activated to dissipate heat from the fuel cell only as needed.

Abstract: Methods, articles, and systems for controlling the internal operating temperature of fuel cell systems, such as planar fuel cell arrays. The heat management system conducts heat away from the fuel cell without disturbing the flow of gases around the fuel cell layer and without the need for the equipment to disturb the flow of gases around the fuel cell layer. The present invention also provides a heat transfer system that has a low thermal mass relative to the fuel cell layer or is thermally isolated from the fuel cell layer such that the heat transfer system will not remove substantial amounts of heat from a fuel cell layer during star-up and can be activated to dissipate heat from the fuel cell only as needed.

Abstract: Purge valves that are manually turned ON but are automatically or electrically turned OFF as the fuel cell's production of electricity reaches a predetermined level, e.g., steady state or thereabout are disclosed. The purge valve may be opened at system start-up, or may be opened at system shut-down so that the purge valve is armed and the fuel cell system is purged at the next start-up. Also disclosed is an integrated fluidic interface module that contains various fluidic components including one of these purge valves. The integrated fluidic interface module can operate passively or without being actively controlled by a processor. Methods of operating a fuel cell system, wherein the fuel cell system is purged at system start-up, are also disclosed. The purging automatically stops when the anode plenum is fully purged and replaced with fuel.

Abstract: Methods, articles, and systems for controlling the internal operating temperature of fuel cell systems, such as planar fuel cell arrays. The heat management system conducts heat away from the fuel cell without disturbing the flow of gases around the fuel cell layer and without the need for the equipment to disturb the flow of gases around the fuel cell layer. The present invention also provides a heat transfer system that has a low thermal mass relative to the fuel cell layer or is thermally isolated from the fuel cell layer such that the heat transfer system will not remove substantial amounts of heat from a fuel cell layer during star-up and can be activated to dissipate heat from the fuel cell only as needed.

Abstract: A cartridge holder houses a fuel cartridge between a first flat plate and a second flat plate, one each side of which is connected by a joining section, in a detachable manner. A fuel cell module and a second fuel cell module are fixed to the outer surface of the first flat plate and the outer surface of the second flat plate, respectively. As the fuel cartridge is housed in the cartridge holder, the first flat plate and the second flat plate are pressed against and then attached firmly to the outer surfaces of the fuel cartridge.