Abstract: In various embodiments, an inference application constructs medical images. The inference application executes a first trained machine learning model on a set of data points associated with a both a medical item and a spectral domain to generate a second model that represents the medical item within the spectral domain. The inference application maps a set of positions to a set of predicted values associated with both the medical item and the spectral domain via the second model. The inference application constructs an image of the medical item based on the first set of predicted values.

Abstract: Methods and systems for processing data to distinguish between a plurality of conditions in lung ultrasound images and, in particular, lung ultrasound images containing B lines. Neural network systems and methods, in which the processor is trained using lung ultrasound images to distinguish between acute respiratory distress syndrome due to COVID-19, acute respiratory distress syndrome due to non-COVID-19 causes, and hydrostatic pulmonary edema.

Abstract: To assist a machine learning environment in modelling a complex physical simulation (such as a numerical simulation or physics simulation), a correlation between input coordinates is determined. For example, a discrete solution (e.g., the correlation between the plurality of input coordinates) may be obtained from a non-discrete (e.g., continuous) physics space by performing a conversion from the physics space to a grid space. This correlation is input along with the coordinates into a machine learning environment to obtain results from the simulation. As a result, instead of implementing resource and power-intensive simulations to solve these computation problems, a machine learning environment implemented using less power and computing resources may solve these computation problems in a faster and more efficient manner.

Abstract: The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a melanoma; an ovarian cancer; or a colorectal cancer). More specifically, the invention concerns the treatment of patients having cancer with an anti-TIGIT antagonist antibody, including treatment with an anti-TIGIT antagonist antibody in a combination therapy.

Abstract: The application discloses an implantable device, comprising a galvanic redox system formed on a body substrate of the implantable device. The implantable device has a non-zero surface potential when it is deployed. The galvanic redox system comprises a first metal site and a second metal site, the first metal site comprising a first metal having a first metal electrode potential (FMEP) and the second metal site comprising a second metal having a second metal electrode potential (SMEP), which FMEP being lower than SMEP and SMEP being substantially different such that the implantable device is galvanized when it is deployed. Methods of making and using the implantabe device are also disclosed.

Abstract: An organ lengthening device comprising a spring-like structure, wherein the surface of the device is covered with micron-size anchors such as hooks, studs or wires made from a biodegradable polymer. The anchors are configured to engage the surface of the organ so that the device will be anchored to the organ. The device, which is inserted into the organ in a compressed position, gradually lengthens over time, thereby lengthening the organ, wherein the anchors are configured to degrade away and eventually allow the device to become disengaged from the organ.

Abstract: A differential global positioning system (DGPS) processor can include an almost fixed integer ambiguity (AFIA) module for generating in real-time a multiple dimensional state vector of integer ambiguities and multiple dimensional corrections. The AFIA module can use double difference (DD) measurements for pseudo-range (PR) and carrier phase (CP) pairs generated from at least three global positioning system (GPS) receivers. A DGPS processor can be included in a high data rate real time attitude determination (RTAD) system to achieve high heading accuracy with high integrity.

Abstract: Liquid titanium oxide compositions, methods for forming such compositions, and methods for etching material layers using such compositions are provided. In accordance with an exemplary embodiment, a liquid titanium oxide composition contains a solvent system, an organotitanate, and a high boiling point solvent having a boiling point in the range of about 140° C. to about 400° C.

Abstract: A system includes a client device and a server including a communication module configured to be accessed by the client device through which a user of the client device connects to another user via one of a plurality of communication services connected to the server, wherein one of the plurality of communication services is telephony.

Abstract: A differential global positioning system (DGPS) processor can include an almost fixed integer ambiguity (AFIA) module for generating in real-time a multiple dimensional state vector of integer ambiguities and multiple dimensional corrections. The AFIA module can use double difference (DD) measurements for pseudo-range (PR) and carrier phase (CP) pairs generated from at least three global positioning system (GPS) receivers. A DGPS processor can be included in a high data rate real time attitude determination (RTAD) system to achieve high heading accuracy with high integrity.

Abstract: A method and system for monitoring and managing applications and services. A repository comprising information identifying a plurality of assets and one or more relationships among the assets is maintained. One or more assets used to support an application are identified, along with one or more applications that are included in a service. Event and performance data are collected by a plurality of tools that perform monitoring and/or managing of the identified assets, the application, and/or the service. The gathered event and performance data is aggregated. The user is provided with a portal to access the aggregated event and performance data. Through this portal, the user can determine an impact of an event or a performance issue on the application or service based on the aggregated event or performance data and the relationships among the assets.

Abstract: A method and system for monitoring and managing applications and services. A repository comprising information identifying a plurality of assets and one or more relationships among the assets is maintained. One or more assets used to support an application are identified, along with one or more applications that are included in a service. Event and performance data are collected by a plurality of tools that perform monitoring and/or managing of the identified assets, the application, and/or the service. The gathered event and performance data is aggregated. The user is provided with a portal to access the aggregated event and performance data. Through this portal, the user can determine an impact of an event or a performance issue on the application or service based on the aggregated event or performance data and the relationships among the assets.

Abstract: A method and system for monitoring and managing applications and services. A repository comprising information identifying a plurality of assets and one or more relationships among the assets is maintained. One or more assets used to support an application are identified, along with one or more applications that are included in a service. Event and performance data are collected by a plurality of tools that perform monitoring and/or managing of the identified assets, the application, and/or the service. The gathered event and performance data is aggregated. The user is provided with a portal to access the aggregated event and performance data. Through this portal, the user can determine an impact of an event or a performance issue on the application or service based on the aggregated event or performance data and the relationships among the assets.

Abstract: A system includes a client device and a server including a communication module configured to be accessed by the client device through which a user of the client device connects to another user via one of a plurality of communication services connected to the server, wherein one of the plurality of communication services is telephony.

Abstract: System and method for sharing data between a 3rd party website and a desktop application program on a user's computer, wherein the web pages of the 3rd party website access data associated with the application program such that the 3rd party web pages drive the data exchange. The 3rd party website is opened within a browser embedded within the desktop application program resident in a memory space on a user's computer and the web pages of the 3rd party website are allowed access to the data associated with the desktop application. Restrictions may be placed on the access given to the 3rd party web pages so that only data and information that is needed is accessed. The data associated with the desktop application may be stored in the memory space of the desktop application program, stored on the user's computer, or stored in a data source operably connected to the desktop application program.

Abstract: Non-fragmenting low friction bioactive absorbable coils are disclosed that improve long-term anatomic results in the endovascular treatment of intracranial aneurysms. The coils are composed of at least one biocompatible and bioabsorbable polymer. The coils are then coated with a polymer to reduce the friction. The coating can contain drugs, such as growth factors, and can be used to accelerate histopathologic transformation in aneurysms. The coil can be a polymer such as polyglycolic acid (PGA), poly-L-lactic acid (PLLA), polycaprolactive, poly-L-lactide, polydioxanone, polycarbonates, polyanhydrides, polyglycolic acid/poly-L-lactic acid copolymers, polyhydroxybutyrate/hydroxyvalerate copolymers, or combinations thereof.

Abstract: Systems and methods are disclosed for detecting or diagnosing diseases by sampling and testing intra-oral fluids.

Abstract: Systems and methods are disclosed for intra-oral delivery of drugs.

Abstract: A method for providing a dental appliance adapted to be worn by a patient by fabricating the dental appliance and coating one or more substances to the dental appliance. The coating substance can be used to strengthen the appliance during use or to deliver drugs.

Abstract: An apparatus for monitoring orthodontic treatment compliance includes an appliance adapted to be worn over one or more teeth; and a compliance indicator mounted on the appliance to indicate compliance.