Abstract: The present invention relates to novel physiological cooling agents, cooling agent mixtures containing said novel agents, mixtures of said cooling agents with flavourings, the use of said cooling agents, and articles and final consumer preparations containing said physiological cooling agents or cooling agent mixtures.

Abstract: The present invention relates to novel cosmetic and therapeutic uses of one or more compounds of the general formula (1) as described herein. Furthermore, the present invention relates to compositions (products or, respectively, formulations), in particular for topical administration, preferably cosmetic or pharmaceutical compositions, comprising or consisting of compound(s) of formula (1) and one or more cosmetically and/or pharmaceutically acceptable carriers. The present invention also relates to novel uses of such compositions according to the invention.

Abstract: The invention relates to aroma preparations that contain (a) a compound of the formula (I) in which R1 represents a linear or branched, saturated or unsaturated hydrocarbon group with 1 to 4 carbon atoms, R2 represents hydrogen or a hydroxyl group and R3 represents hydrogen, a methyl or methoxy group, or an essential oil containing one or more compounds of the formula (I) and at least one menthol compound.

Abstract: Suggested is a cooling preparation comprising phenylalkenals and homovanillic acid esters.

Abstract: The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.

Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

Abstract: Suggested is a cosmetic blend, comprising or consisting of (a) at least one TRPV1 and/or TRPV3 modulator and (b1) at least one 1,2-alkandiol having 5 to 12 carbon atoms and/or (b2) at least one polyol having 3 to 12 carbon atoms and 3 to 6 hydroxyl groups.

Abstract: The present invention is the use of a compound of formula (I) or a (pharmaceutically) acceptable salt thereof, wherein (a) X denotes CH?CH or CZ1=CZ2, wherein if Z1 is H then Z2 denotes a radical selected from the group consisting of OH, NH2, NHMe, NMe2, OMe and OEt and if Z2 is H then Z1 denotes a radical selected from the group consisting of OH, NH2, NHMe, NMe2, OMe and OEt, Y denotes a radical selected from the group consisting of NH2, NHMe, NMe2, NHEt, O—(CH2)n—OH, wherein n is 2 to 5 and R denotes a radical selected from the group consisting of H, OH, Me, Et, OMe, OEt, NH2, NHMe, NMe2, NHEt and NEt2, or (b) X denotes O, Y denotes a radical selected from the group consisting of NH2, NHMe, NMe2, NHEt, O—(CH2)n—OH and OMe, wherein n is 2 to 5 and R denotes H, OH, Me, Et, OMe, OEt, NH2, NHMe, NMe2, NHEt, NEt2 as antimicrobial agent as well as to composition comprising said agent.

Abstract: Mixtures comprising a selected cooling active ingredient (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide and at least one other substance which acts as a solvent for (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide, wherein the substance is selected form the group consisting of benzyl benzoate, diethyl succinate, triethyl citrate, triacetin, ethanol, peppermint oil, anethol, optamint, propylene glycol, further cooling active ingredients or mixtures thereof.

Abstract: The present invention relates to novel cosmetic and therapeutic uses of one or more compounds of the general formula (1) as described herein. Furthermore, the present invention relates to compositions (products or, respectively, formulations), in particular for topical administration, preferably cosmetic or pharmaceutical compositions, comprising or consisting of compound(s) of formula (1) and one or more cosmetically and/or pharmaceutically acceptable carriers. The present invention also relates to novel uses of such N compositions according to the invention.

Abstract: The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.

Abstract: Suggested is a composition comprising (a) at least one lactate ester and (b1) at least one second compound selected from the group encompassing benzaldehyde derivatives, aromatic aldehydes and aromatic acids.

Abstract: Suggested is a cosmetic blend, comprising or consisting of (a) at least one TRPV1 and/or TRPV3 modulator and (b1) at least one 1,2-alkandiol having 5 to 12 carbon atoms and/or (b2) at least one polyol having 3 to 12 carbon atoms and 3 to 6 hydroxyl groups.

Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

Abstract: The invention relates to aroma preparations that contain (a) a compound of the formula (I) in which R1 represents a linear or branched, saturated or unsaturated hydrocarbon group with 1 to 4 carbon atoms, R2 represents hydrogen or a hydroxyl group and R3 represents hydrogen, a methyl or methoxy group, or an essential oil containing one or more compounds of the formula (I) and at least one menthol compound.

Abstract: The present invention is the use of a compound of formula (I) or a (pharmaceutically) acceptable salt thereof, wherein (a) X denotes CH?CH or CZ1=CZ2, wherein if Z1 is H then Z2 denotes a radical selected from the group consisting of OH, NH2, NHMe, NMe2, OMe and OEt and if Z2 is H then Z1 denotes a radical selected from the group consisting of OH, NH2, NHMe, NMe2, OMe and OEt, Y denotes a radical selected from the group consisting of NH2, NHMe, NMe2, NHEt, O—(CH2)n—OH, wherein n is 2 to 5 and R denotes a radical selected from the group consisting of H, OH, Me, Et, OMe, OEt, NH2, NHMe, NMe2, NHEt and NEt2, or (b) X denotes O, Y denotes a radical selected from the group consisting of NH2, NHMe, NMe2, NHEt, O—(CH2)n—OH and OMe, wherein n is 2 to 5 and R denotes H, OH, Me, Et, OMe, OEt, NH2, NHMe, NMe2, NHEt, NEt2 as anti-microbial agent as well as to composition comprising said agent.

Abstract: Mixtures comprising a selected cooling active ingredient (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide and at least one other substance which acts as a solvent for (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide, wherein the substance is selected form the group consisting of benzyl benzoate, diethyl succinate, triethyl citrate, triacetin, ethanol, peppermint oil, anethol, optamint, propylene glycol, further cooling active ingredients or mixtures thereof.

Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.