Patents by Inventor Bernard F. Grisoni
Bernard F. Grisoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6692525Abstract: An intraocular lens for implantation in an eye comprising an optic configured so that the optic can be deformed to permit the intraocular lens to be passed through an incision into the eye. A peripheral zone circumscribes the optical zone of the optic and one or more fixation members coupled to the peripheral zone and extending outwardly from the peripheral zone to retain the optic in the eye are provided. In one embodiment the fixation member or members are located so that the optical zone is free of such member or members. The peripheral zone preferably has a maximum axial thickness which is larger than the maximum axial thickness of the periphery of the optical zone.Type: GrantFiled: February 18, 2000Date of Patent: February 17, 2004Assignee: Advanced Medical Optics, Inc.Inventors: Daniel G. Brady, Christopher Doyle, Bernard F. Grisoni
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Publication number: 20040025376Abstract: An insole for use with footwear includes a first layer including a heel portion of a first thickness, a mid portion connected to a front section of the heel portion and having a substantially constant thickness which is much less than the first thickness, and having an upward curvature, an upper surface extending along the mid and heel portions and on which a person stands, and a lower surface extending along the mid and heel portions, the lower surface including a shallow recess in the mid portion, the first layer being made of a material of a first hardness; and a flexible and resilient, thin arch spring insert of a substantially constant thickness secured in the recess and following the curvature of the mid portion, the arch spring insert being made of a material of a second hardness which is greater than the first hardness.Type: ApplicationFiled: August 6, 2002Publication date: February 12, 2004Applicant: Schering CorporationInventors: Bernard F. Grisoni, Philip Yang, Harold A. Howlett, Laura J. Crane
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Publication number: 20020045938Abstract: An intraocular lens for implantation in an eye comprising an optic configured so that the optic can be deformed to permit the intraocular lens to be passed through an incision into the eye. A peripheral zone circumscribes the optical zone of the optic and one or more fixation members coupled to the peripheral zone and extending outwardly from the peripheral zone to retain the optic in the eye are provided. In one embodiment the fixation member or members are located so that the optical zone is free of such member or members. The peripheral zone preferably has a maximum axial thickness which is larger than the maximum axial thickness of the periphery of the optical zone.Type: ApplicationFiled: February 18, 2000Publication date: April 18, 2002Inventors: Daniel G Brady, Christopher Doyle, Bernard F. Grisoni
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Patent number: 6139576Abstract: New intraocular lenses (IOLs) and methods for producing IOLs are disclosed. The present methods include a combination of steps which increase the pull strength between the fixation member of the IOL and the optic of the IOL without requiring sophisticated high frequency corona discharge activation or plasma activation of the fixation member. The fixation members are doubly coated with primer components and silicone polymeric material precursor compositions before being secured to the optics. In addition, the optic members employed in the present intraocular lenses can be formed, for example, molded, without recesses to accommodate the fixation members. Thus, such recesses can be formed and provided with a quantity of the above-noted precursor composition after the optic members are produced. The doubly coated fixation members are then placed in the recesses and secured to the optic members. The present methods are straight forward, easy to practice and are cost effective in producing high quality IOLs.Type: GrantFiled: January 6, 1999Date of Patent: October 31, 2000Assignee: AllerganInventors: Christopher E. Doyle, Bernard F. Grisoni, Richard S. Graham
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Patent number: 5895609Abstract: New intraocular lenses (IOLs) and methods for producing IOLs. The present methods include a combination of steps which increase the pull strength between the fixation member of the IOL and the optic of the IOL without requiring sophisticated high frequency corona discharge activation or plasma activation of the fixation member. The fixation members are doubly coated with primer components and silicone polymeric material precursor compositions before being secured to the optics. In addition, the optic members employed in the present invention can be formed, for example, molded, without recesses to accommodate the fixation members. Thus, such recesses can be formed and provided with a quantity of the above-noted precursor composition after the optic members are produced. The doubly coated fixation members are then placed in the recesses and secured to the optic members. The present methods are straight forward, easy to practice and are cost effective in producing high quality IOLs.Type: GrantFiled: May 31, 1995Date of Patent: April 20, 1999Assignee: AllerganInventors: Christopher E. Doyle, Bernard F. Grisoni, Richard S. Graham
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Patent number: 5762837Abstract: New intraocular lenses and methods for producing such lenses. In one embodiment, the intraocular lens includes an optic; and at least one fixation member, e.g., haptic, secured to and extending from the optic, the fixation member being made from a rotated item including a polymer, the rotated item being derived by placing an item having a thickness and the same chemical make-up as the rotated item between two surfaces so that the surfaces each contact the item and are separated by the thickness, and rotating at least a portion of one of the surfaces around an axis substantially parallel to the thickness, provided that the intraocular lens has increased tensile strength relative to a substantially identical intraocular lens made from the original item. Methods of making intraocular lenses are also included.Type: GrantFiled: October 11, 1996Date of Patent: June 9, 1998Inventors: Bernard F. Grisoni, Glenn R. Sussman
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Patent number: 5756127Abstract: A bioresorbable string of implantable beads in which the beads consist essentially of calcium sulfate and a quantity of a drug suitable for treating tissue disorders, and in which both the beads and the line that joins the beads together are bioresorbable.Type: GrantFiled: October 29, 1996Date of Patent: May 26, 1998Assignee: Wright Medical Technology, Inc.Inventors: Bernard F. Grisoni, Steve Gitelis, Timothy L. Harrison, Jack E. Parr, Ben R. Shappley
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Patent number: 5653753Abstract: A method of inserting a foldable intraocular lens (IOL) into the eye of a patient comprising holding a foldable IOL with forceps with the IOL being in a first folded condition in which the IOL has at least one fold and folding the IOL into a second folded condition in which the IOL has at least the first fold and a second fold. The IOL is retained in the second folded condition in a tubular member. The IOL is then transferred in substantially the second folded condition into the eye of the patient.Type: GrantFiled: June 7, 1995Date of Patent: August 5, 1997Assignee: AllerganInventors: Daniel G. Brady, Bernard F. Grisoni
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Patent number: 5611968Abstract: New intraocular lenses and methods for producing such lenses. In one embodiment, the intraocular lens includes an optic; and at least one fixation member, e.g., haptic, secured to and extending from the optic, the fixation member being made from a rotated item including a polymer, the rotated item being derived by placing an item having a thickness and the same chemical make-up as the rotated item between two surfaces so that the surfaces each contact the item and are separated by the thickness, and rotating at least a portion of one of the surfaces around an axis substantially parallel to the thickness, provided that the intraocular lens has increased tensile strength relative to a substantially identical intraocular lens made from the original item. Methods of making intraocular lenses are also included.Type: GrantFiled: August 16, 1994Date of Patent: March 18, 1997Assignee: AllerganInventors: Bernard F. Grisoni, Glenn R. Sussman
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Patent number: 5585049Abstract: A method of making an intraocular lens including attaching a fixation member to an optic to form an IOL assembly with a length of the fixation member between a location on a peripheral surface of the optic and a distal end of the fixation member being elongated and substantially straight. The substantially straight length of the fixation member is permanently deformed into a curved configuration suitable for implantation in an eye of a patient.Type: GrantFiled: September 2, 1994Date of Patent: December 17, 1996Assignee: AllerganInventors: Bernard F. Grisoni, Christopher E. Doyle
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Patent number: 5527415Abstract: New intraocular lenses (IOLs) and methods for producing IOLs are disclosed. The present methods include a combination of steps which increase the pull strength between the fixation member of the IOL and the optic of the IOL without requiring sophisticated high frequency corona discharge activation or plasma activation of the fixation member. The fixation members are doubly coated with primer components and silicone polymeric material precursor compositions before being secured to the optics. In addition, the optic members employed in the present invention can be formed, for example, molded, without recesses to accommodate the fixation members. Thus, such recesses can be formed and provided with a quantity of the above-noted precursor composition after the optic members are produced. The doubly coated fixation members are then placed in the recesses and secured to the optic members. The present methods are straight forward, easy to practice and are cost effective in producing high quality IOLs.Type: GrantFiled: March 28, 1995Date of Patent: June 18, 1996Assignee: Allergan, Inc.Inventors: Christopher E. Doyle, Bernard F. Grisoni, Richard S. Graham
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Patent number: 5476513Abstract: An intraocular lens for implantation in an eye comprising an optic configured so that the optic can be deformed to permit the intraocular lens to be passed through an incision into the eye. A peripheral zone circumscribes the optical zone of the optic and one or more fixation members coupled to the peripheral zone and extending outwardly from the peripheral zone to retain the optic in the eye are provided. In one embodiment the fixation member or members are located so that the optical zone is free of such member or members. The peripheral zone preferably has a maximum axial thickness which is larger than the maximum axial thickness of the periphery of the optical zone.Type: GrantFiled: February 19, 1993Date of Patent: December 19, 1995Assignee: Allergan, Inc.Inventors: Daniel G. Brady, Christopher Doyle, Bernard F. Grisoni
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Patent number: 5423929Abstract: New intraocular lenses (IOLs) and methods for producing IOLs are disclosed. The present methods include a combination of steps which increase the pull strength between the fixation member of the IOL and the optic of the IOL without requiring sophisticated high frequency corona discharge activation or plasma activation of the fixation member. The fixation members are doubly coated with primer components and silicone polymeric material precursor compositions before being secured to the optics. In addition, the optic members employed in the present invention can be formed, for example, molded, without recesses to accommodate the fixation members. Thus, such recesses can be formed and provided with a quantity of the above-noted precursor composition after the optic members are produced. The doubly coated fixation members are then placed in the recesses and secured to the optic members. The present methods are straight forward, easy to practice and are cost effective in producing high quality IOLs.Type: GrantFiled: October 27, 1993Date of Patent: June 13, 1995Assignee: Allergan, Inc.Inventors: Christopher E. Doyle, Bernard F. Grisoni, Richard S. Graham
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Patent number: 5344449Abstract: New intraocular lenses, fixation member assemblies for use in such lenses and methods for making the same are disclosed. In one embodiment, the present invention involves a method for producing a fixation member assembly which comprises exposing a fixation member component to a first plasma at conditions effective to enhance, relative to a substantially identical fixation member component which is not subjected to the exposing step, the bondability between the fixation member component and a polymeric coating to be located on the fixation member component; and exposing the fixation member to a second plasma in the presence of at least one material selected from polymeric components, polymerizable components and mixtures thereof at conditions effective to form the polymeric coating located on the fixation member component. Enhanced bondability between the polymeric coating-containing fixation member component and the optic of the intraocular lens and/or enhanced biocompatibility are preferably provided.Type: GrantFiled: July 6, 1993Date of Patent: September 6, 1994Assignee: Allergan, Inc.Inventors: F. Richard Christ, James E. Francese, Bernard F. Grisoni
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Patent number: 5262097Abstract: New intraocular lenses, fixation member assemblies for use in such lenses and methods for making the same. In one embodiment, the present invention involves a method for producing a fixation member assembly which includes exposing a fixation member component to a first plasma at conditions effective to enhance, relative to a substantially identical fixation member component which is not subjected to the exposing step, the bondability between the fixation member component and a polymeric coating to be located on the fixation member component; and exposing the fixation member to a second plasma in the presence of at least one material selected from polymeric components, polymerizable components and mixtures thereof at conditions effective to form the polymeric coating located on the fixation member component. Enhanced bondability between the polymeric coating-containing fixation member component and the optic of the intraocular lens and/or enhanced biocompatibility are preferably provided.Type: GrantFiled: January 23, 1992Date of Patent: November 16, 1993Assignee: Allergan, Inc.Inventors: F. Richard Christ, James E. Francese, Bernard F. Grisoni
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Patent number: 5201763Abstract: An intraocular lens for implantation in an eye comprising a deformable silicone optic configured so that the optic can be deformed to permit the intraocular lens to be passed through a scleral tunnel incision no longer than about 3.2 mm into the eye. The intraocular lens can be provided in a range of diopter powers. When the intraocular lens is implanted in the eye, the optic has sufficient rigidity to be substantially free of optical distortion resulting from force from the eye acting on the intraocular lens and the optic is of sufficient size to substantially prevent glare resulting from interaction of light and the periphery of the optic.Type: GrantFiled: February 28, 1992Date of Patent: April 13, 1993Assignee: Allergan, Inc.Inventors: Dan G. Brady, Bernard F. Grisoni, Christopher E. Doyle
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Patent number: 5010115Abstract: The invention relates to silicone foams.It concerns a silicone foam composition consisting of two or more components, the said composition being capable of rapid cure at 20.degree. C. on mixing its components, to give a foamed mass having a density of less than 200 kg/m.sup.3, characterised in that it comprises (A) one or more polysiloxanes having at least three alkylhydrogensiloxane units per molecule, (B) one or more polydiorganosiloxanes having at least two siloxane units of the formula ##EQU1## in which R represents a monovalent hydrocarbon group containing from 1 to 20 carbon atoms, Q represents a hydroxylated alkylene or alkoxylene chain, a has a value of 0, 1 or 2 and the value of b is 1 or 2 and c is a platinum catalyst for promoting the reaction between the components.Useful for the production of medical dressings.Type: GrantFiled: October 16, 1990Date of Patent: April 23, 1991Assignee: Dow Corning France S. A.Inventor: Bernard F. Grisoni
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Patent number: D456125Type: GrantFiled: May 25, 2001Date of Patent: April 30, 2002Assignee: Schering-Plough HealthCare Products, Inc.Inventors: Bernard F. Grisoni, Richard T. Avent, Laura J. Crane
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Patent number: D456126Type: GrantFiled: May 25, 2001Date of Patent: April 30, 2002Assignee: Schering-Plough HealthCare Products, Inc.Inventors: Bernard F. Grisoni, Richard T. Avent, Laura J. Crane
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Patent number: D456127Type: GrantFiled: May 25, 2001Date of Patent: April 30, 2002Assignee: Schering-Plough HealthCare Products, Inc.Inventors: Bernard F. Grisoni, Richard T. Avent, Laura J. Crane