Patents by Inventor Bernard GRIMAUD

Bernard GRIMAUD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for Preparing Sartan Active Compounds Having a Tetrazole Ring
    Publication number: 20230119053
    Abstract: The present disclosure relates to a process for manufacturing at least one sartan active compound of formula (I) wherein R is selected from a group of formulas (1), (2), (3), (4) and (5), comprising the tetrazolylation of one compound of formula (II) wherein R is as previously defined, in a reactional medium with at least one azide derivative, wherein benzylic azide impurities formed during said tetrazolylation are converted into aldehyde derivatives.
    Type: Application
    Filed: September 30, 2022
    Publication date: April 20, 2023
    Applicant: SANOFI
    Inventors: Paul CRUCIANI, Isabelle GALIBOURG, Bernard GRIMAUD
  • Process for synthesizing keto benzofuran derivatives
    Patent number: 8962869
    Abstract: The invention relates to a method for synthesizing benzofuran derivatives, in particular the dronedarone of formula (D), including carrying out a Fries rearrangement reaction using a sulfonamido-benzofuran ester intermediate.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: February 24, 2015
    Assignee: Sanofi
    Inventors: Bernard Grimaud, Pierre-Jean Grossi
  • Ketobenzofuran derivatives, method for synthesizing same, and intermediates
    Patent number: 8796489
    Abstract: The present disclosure relates to ketobenzofuran derivatives of the general formula (I): as well as to a method of synthesizing the same by coupling a quinonimine and an enaminone by a Nenitzescu reaction and to the intermediates of the synthesis thereof.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: August 5, 2014
    Assignee: Sanofi
    Inventors: Frédéric Bailly, Bernard Grimaud, Irina Malejonock, Philippe Vayron
  • PROCESS FOR SYNTHESIZING KETO BENZOFURAN DERIVATIVES
    Publication number: 20140046078
    Abstract: The invention relates to a method for synthesizing benzofuran derivatives, in particular the dronedarone of formula (D), including carrying out a Fries rearrangement reaction using a sulfonamido-benzofuran ester intermediate.
    Type: Application
    Filed: March 23, 2012
    Publication date: February 13, 2014
    Applicant: SANOFI
    Inventors: Bernard Grimaud, Pierre-Jean Grossi
  • PROCESS FOR SYNTHESIZING KETO-BENZOFURAN DERIVATIVES
    Publication number: 20140018553
    Abstract: The invention relates to a process for synthesizing benzofuran derivatives, in particular dronedarone of formula (D), comprising a step of Friedel-Crafts acylation starting from a sulfonamido-benzofuran ester intermediate.
    Type: Application
    Filed: March 23, 2012
    Publication date: January 16, 2014
    Applicant: SANOFI
    Inventors: Bernard Grimaud, Pierre-Jean Grossi
  • KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESIZING SAME, AND INTERMEDIATES
    Publication number: 20130012729
    Abstract: The present disclosure relates to ketobenzofuran derivatives of the general formula (I): as well as to a method of synthesizing the same by coupling a quinonimine and an enaminone by a Nenitzescu reaction and to the intermediates of the synthesis thereof.
    Type: Application
    Filed: August 30, 2012
    Publication date: January 10, 2013
    Applicant: SANOFI
    Inventors: Frederic BAILLY, Bernard GRIMAUD, Irina MALEJONOCK, Philippe VAYRON