Patents by Inventor Bernard Raizon

Bernard Raizon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5192797
    Abstract: A compound which is a 2-aminoalkyl-5-arylalkyl-1,3-dioxane of general formula (I) ##STR1## in which m represents 0 or 1;n represents 1, 2, 3 or 4;R.sub.1 represents hydrogen or methyl;R.sub.2 represents hydrogen, methyl or an alkanoyl group of the general formula COR' in which R' represents a hydrogen atom or a linear or branched C.sub.1 -C.sub.4 -alkyl group, or an alkoxycarbonyl group of the general formula COOR" in which R" represents a linear or branched C.sub.1 -C.sub.4 -alkyl group; and Ar represents either a phenyl group optionally carrying one or two substituents selected from halogen, C.sub.1 -C.sub.4 alkyl, methoxy and trifluoromethyl, or a naphthalen-1-yl or naphthalen-2-yl group optionally carrying a substituent selected from halogen, methyl, methoxy and cyclopropylmethoxy groups,in the form of a cis- or trans-stereoisomer, and in the form of a free base or an acid addition salt thereof and its therapeutic use.
    Type: Grant
    Filed: June 14, 1991
    Date of Patent: March 9, 1993
    Assignee: Synthelabo
    Inventors: Bernard Raizon, Yannick Evanno, Odette LeGalloudec
  • Patent number: 4663350
    Abstract: Diphenylazomethine derivatives of formula (I) ##STR1## wherein R.sub.1 is hydrogen or methyl and R.sub.2 is an --OH,--OM (M=alkaline metal or alkaline earth metal), --NH.sub.2 or --O(C.sub.1-4 alkyl) group, and which are in the form of cis or trans isomers or mixtures thereof, have central nervous system activity and can be used as antidepressants and anticonvulsants.
    Type: Grant
    Filed: September 26, 1985
    Date of Patent: May 5, 1987
    Assignee: Synthelabo
    Inventors: Alexander Wick, Bernard Raizon
  • Patent number: 4638080
    Abstract: Process for preparing diphenylazomethines of formula (II) ##STR1## by decarboxylation of diphenylazomethines of formula (I) ##STR2## in which X.sub.1 and X.sub.2 each denote, independently of each other, a hydrogen atom or a halogen atom or a methyl radical,R.sub.1 is H or linear or branched (C.sub.1-4) alkyl radical,R.sub.2 is the radical COOH, a linear or branched (C.sub.1-4) alkyl radical, the radical CONH.sub.2 or a linear or branched COO(C.sub.1-4) alkyl radical, andR.sub.3 denotes a hydrogen atom or the methyl radical.
    Type: Grant
    Filed: February 25, 1986
    Date of Patent: January 20, 1987
    Assignee: Synthelabo
    Inventors: Bernard Raizon, Guy Rossey, Alexander Wick
  • Patent number: 4478851
    Abstract: Benzylidene derivatives of the formula: ##STR1## in which each of X.sub.1, X.sub.2, X.sub.3 and X.sub.4 independently of one another represents hydrogen, halogen, a linear or branched alkyl radical of 1 to 4 carbon atoms, CF.sub.3, NO.sub.2, phenyl, methoxy, or amino, at least two of the substituents X.sub.1, X.sub.2, X.sub.3 and X.sub.4 being different from hydrogen, and R represents a linear or branched alkyl radical of 1 to 16 carbon atoms or an alkenyl radical of 2 to 8 carbon atoms, which may be produced by reaction of the corresponding ketones with an amine, are active on the central nervous system, especially as anti-convulsants.
    Type: Grant
    Filed: May 2, 1983
    Date of Patent: October 23, 1984
    Assignee: Synthelabo
    Inventors: Jean-Pierre Kaplan, Bernard Raizon
  • Patent number: 4400536
    Abstract: Benzylidene derivatives of the formula: ##STR1## in which each of X.sub.1, X.sub.2, X.sub.3 and X.sub.4 independently of one another represents hydrogen, halogen, a linear or branched alkyl radical of 1 to 4 carbon atoms, CF.sub.3, NO.sub.2, phenyl, methoxy, or amino, at least two of the substituents X.sub.1, X.sub.2, X.sub.3 and X.sub.4 being different from hydrogen, and R represents a linear or branched alkyl radical of 1 to 16 carbon atoms or an alkenyl radical of 2 to 8 carbon atoms, which may be produced by reaction of the corresponding ketones with an amine, are active on the central nervous system, especially as anti-convulsants.
    Type: Grant
    Filed: February 11, 1981
    Date of Patent: August 23, 1983
    Assignee: Synthelabo
    Inventors: Jean-Pierre Kaplan, Bernard Raizon