Patents by Inventor Bernard Salafsky

Bernard Salafsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Parasite-derived anti-inflammatory immunomodulatory protein
    Publication number: 20050037970
    Abstract: A protein with anti-inflammatory, and immunomodulatory functions was identified and isolated from the excretory/secretions of a human parasite, Schistosoma mansoni. This protein, designated herein as Sm 16.8, is released by schistosomes upon entry into human skin. Under in vitro conditions Sm 16.8 is shown to stimulate the production of anti-inflammatory cytokine Interleukin-1 receptor antagonist (IL-1ra) in human keratinocytes and transcriptionally down regulate the production of pro-inflamnmatory cytokines IL-1 and IL-1.
    Type: Application
    Filed: September 20, 2004
    Publication date: February 17, 2005
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Bernard Salafsky, Ramaswamy Kalyanasundaram, Takeshi Shibuya
  • Parasite-derived anti-inflammatory immunomodulatory protein
    Publication number: 20020176862
    Abstract: A protein with anti-inflammatory, and immunomodulatory functions was identified and isolated from the excretory/secretions of a human parasite, Schistosoma mansoni. This protein, designated herein as Sm 16.8, is released by schistosomes upon entry into human skin. Under in vitro conditions Sm 16.8 is shown to stimulate the production of anti-inflammatory cytokine Interleukin-1 receptor antagonist (IL-1ra) in human keratinocytes and transcriptionally down regulate the production of pro-inflammatory cytokines IL-1 and IL-1.
    Type: Application
    Filed: April 2, 2002
    Publication date: November 28, 2002
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Bernard Salafsky, Ramaswamy Kalyanasundaram, Takeshi Shibuya
  • Anti-parasitic action of N,N-diethyl-m-toluamide (deet) and formulations that prolong its activity in the skin
    Patent number: 6447801
    Abstract: Novel formulations of DEET are provided which comprise liposomes and other carriers. Methods and materials for preventing Schistomiasis and other parasitic and microbial diseases are also provided. Also provided are improved materials and methods for repelling biting insects.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: September 10, 2002
    Inventors: Bernard Salafsky, Ramaswamy Kalyanasundaram, Takeshi Shibuya
  • Parasite-derived anti-inflammatory immunomodulatory protein
    Patent number: 6372219
    Abstract: A protein with anti-inflammatory, and immunomodulatory functions was identified and isolated from the excretory/secretions of a human parasite Schistosoma mansoni. This protein, designated herein as Sm 16.8, is released by schistosomes upon entry into human skin. Under in vitro conditions Sm 16.8 is shown to stimulate the production of anti-inflammatory cytokine Interleukin-1 receptor antagonist (IL-1ra) in human keratinocytes and transciptionally down regulate the production of proinflammatory cytokines IL-1 &agr; and IL-1 &bgr;.
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: April 16, 2002
    Inventors: Bernard Salafsky, Ramaswamy Kalyanasundaram, Takeshi Shibuya