Patents by Inventor Bernardo M. da Costa

Bernardo M. da Costa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF FATTY ACID DERIVATIVES
    Publication number: 20240150774
    Abstract: The disclosure relates to recombinant host cells including strain modifications effective to improve titer, yield and/or productivity of fatty acid derivatives. The disclosure further relates to cell cultures including the recombinant host cells for the fermentative production of fatty acid derivatives and compositions thereof.
    Type: Application
    Filed: June 29, 2023
    Publication date: May 9, 2024
    Inventors: Derek L. GREENFIELD, Andreas W. Schirmer, Elizabeth J. Clarke, Eli S. Groban, Bernardo M. Da Costa, Zhihao Hu, Kevin Holden, Noah Helman
  • Production Of Fatty Acid Derivatives
    Publication number: 20210348173
    Abstract: The disclosure relates to recombinant host cells including strain modifications effective to improve titer, yield and/or productivity of fatty acid derivatives. The disclosure further relates to cell cultures including the recombinant host cells for the fermentative production of fatty acid derivatives and compositions thereof.
    Type: Application
    Filed: June 1, 2021
    Publication date: November 11, 2021
    Inventors: Derek L. GREENFIELD, Andreas W. SCHIRMER, Elizabeth J. CLARKE, Eli S. GROBAN, Bernardo M. DA COSTA, Zhihao HU, Kevin HOLDEN, Noah HELMAN
  • Enzyme Variants With Improved Ester Synthase Properties
    Publication number: 20210309979
    Abstract: The disclosure relates to enzyme variants with improved ester synthase properties for the production of fatty acid esters. Further contemplated are recombinant host cells that express such variants, cell cultures comprising the recombinant host cells and fatty acid ester compositions produced by such recombinant host cells.
    Type: Application
    Filed: December 9, 2020
    Publication date: October 7, 2021
    Inventors: Andrew M. SHUMAKER, Bernardo M. DA COSTA, Kevin HOLDEN, Louis G. HOM, Tarah S. BARON, Noah HELMAN
  • Production of fatty acid derivatives
    Patent number: 11060099
    Abstract: The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: July 13, 2021
    Assignee: Genomatica, Inc.
    Inventors: Derek L. Greenfield, Andreas W. Schirmer, Elizabeth J. Clarke, Eli S. Groban, Bernardo M. Da Costa, Zhihao Hu, Kevin Holden, Noah Helman
  • Enzyme variants with improved ester synthase properties
    Patent number: 10894953
    Abstract: The disclosure relates to enzyme variants with improved ester synthase properties for the production of fatty acid esters. Further contemplated are recombinant host cells that express such variants, cell cultures comprising the recombinant host cells and fatty acid ester compositions produced by such recombinant host cells.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: January 19, 2021
    Assignee: Genomatica, Inc.
    Inventors: Andrew M. Shumaker, Bernardo M. da Costa, Kevin Holden, Louis G. Hom, Tarah S. Baron, Noah Helman
  • ENZYME VARIANTS WITH IMPROVED ESTER SYNTHASE PROPERTIES
    Publication number: 20180327728
    Abstract: The disclosure relates to enzyme variants with improved ester synthase properties for the production of fatty acid esters. Further contemplated are recombinant host cells that express such variants, cell cultures comprising the recombinant host cells and fatty acid ester compositions produced by such recombinant host cells.
    Type: Application
    Filed: January 18, 2018
    Publication date: November 15, 2018
    Inventors: Andrew M. SHUMAKER, Bernardo M. da Costa, Kevin HOLDEN, Louis G. HOM, Tarah S. BARON, Noah HELMAN
  • Enzyme variants with improved ester synthase properties
    Patent number: 9879239
    Abstract: The disclosure relates to enzyme variants with improved ester synthase properties for the production of fatty acid esters. Further contemplated are recombinant host cells that express such variants, cell cultures comprising the recombinant host cells and fatty acid ester compositions produced by such recombinant host cells.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 30, 2018
    Assignee: REG LIFE SCIENCES, LLC
    Inventors: Andrew M. Shumaker, Bernardo M. Da Costa, Kevin Holden, Louis G. Hom, Tarah S. Baron, Noah Helman
  • PRODUCTION OF FATTY ACID DERIVATIVES
    Publication number: 20180010137
    Abstract: The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell.
    Type: Application
    Filed: July 14, 2017
    Publication date: January 11, 2018
    Inventors: Derek L. GREENFIELD, Andreas W. Schirmer, Elizabeth J. CLARKE, Eli S. GROBAN, Bernardo M. Da Costa, Zhihao Hu, Kevin Holden, Noah Helman
  • ENZYME VARIANTS WITH IMPROVED ESTER SYNTHASE PROPERTIES
    Publication number: 20150299679
    Abstract: The disclosure relates to enzyme variants with improved ester synthase properties for the production of fatty acid esters. Further contemplated are recombinant host cells that express such variants, cell cultures comprising the recombinant host cells and fatty acid ester compositions produced by such recombinant host cells.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 22, 2015
    Applicant: REG Life Sciences, LLC.
    Inventors: Andrew M. SHUMAKER, Bernardo M. DA COSTA, Kevin HOLDEN, Louis G. HOM, Tarah S. BARON, Noah HELMAN
  • PRODUCTION OF FATTY ACID DERIVATIVES
    Publication number: 20150064782
    Abstract: The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell.
    Type: Application
    Filed: April 2, 2013
    Publication date: March 5, 2015
    Applicant: REG LIFE SCIENCES, LLC
    Inventors: Derek L. Greenfield, Andreas W. Schirmer, Elizabeth J. Clarke, Eli S. Groban, Bernardo M. Da Costa, Zhihao Hu
  • COMPOSITIONS COMPRISING AND METHODS FOR PRODUCING BETA-HYDROXY FATTY ACID ESTERS
    Publication number: 20140215904
    Abstract: Disclosed are fatty ester compositions comprising beta-hydroxy fatty esters, as well as methods for producing beta-hydroxy fatty esters, and recombinant microorganisms useful in methods of producing beta-hydroxy fatty esters
    Type: Application
    Filed: March 30, 2012
    Publication date: August 7, 2014
    Applicant: LS9, Inc.
    Inventors: Archana Pandey, Mathew A Rude, Fernando A Sanchez-Riera, Bernardo M. da Costa