Abstract: The present invention relates to the use of (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of formula (I), prefer-ably in form of one of its salts or solvates or hydrates, preferably (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid in form of monohydrate (I) of formula (I-M-I) or (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)-ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid inform of mono hydrate (II) of formula (I-M-II), in the inhalative treatment of cardiopulmonary and pulmonary disorders, such as pulmonary arterial hypertension (P AH), chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary hypertension (PH) associated with chronic lung disease (PH group 3) such as pulmonary hypertension in chronic obstructive pulmo

Abstract: The present invention relates to a novel and improved process for preparing (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluo-romethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of the formula (I) and to novel crystalline forms of it, which is i.a. the pseudopolymorphic form monohydrate I (I-M-I) or the pseudopolymorphic form monohydrate II (I-M-II), furthermore the present invention relates to a novel and selective crystallization process for preparation of the pseudopolymorphic form monohydrate I (I-M-I) or the pseudopolymorphic form monohydrate II (I-M-II), preferably monohydrate I of formula (I-M-I) and to pharmaceutical compositions comprising monohydrate I of formula (I-M-I) and to its use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiopulmonary and cardiovascular diseases.

Abstract: The invention provides a circuit for controlling a cathode ray tube. The circuit comprises a source of input color signals (Uin(R), Uin(G), Uin(B)) for the primary colors of the cathode ray tube. Output amplifiers are coupled to the source of color input signals and to electron guns of the cathode ray tube. Finally, limiting means are provided to limit the color input signals to a predetermined threshold value. In this way the output amplifiers are prevented from saturation and undesirable smears do not appear on the screen. In an advantageous embodiment the limiting means are realized by a diode biased in reverse direction.

Abstract: The invention provides a circuit for controlling a cathode ray tube. The circuit comprises a source of input colour signals (Uin(R), Uin(G), Uin(B)) for the primary colours of the cathode ray tube. Output amplifiers are coupled to the source of colour input signals and to electron guns of the cathode ray tube. Finally, limiting means are provided to limit the colour input signals to a predetermined threshold value. In this way the output amplifiers are prevented from saturation and undesirable smears do not appear on the screen. In an advantageous embodiment the limiting means are realized by a diode biased in reverse direction.

Abstract: A circuit for controlling the picture tube in a television receiver. In order to generate a high peak white on the screen of the picture tube, it is desirable to drive the output amplifiers at full output. Because of tolerances, for example in the cutoff calibration, the transparency of the picture tube glass, fluctuations in the input signal etc., driving the video output stages to full output may drive the output stages into saturation and disturbances in the form of so-called smears can occur in the picture. The present invention permits the output stages to be driven to full output as far as the highest peak white without the output amplifiers going into saturation and causing disturbances in the form of smears in the picture.