Patents by Inventor Bernd Riedl

Bernd Riedl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLIC CHEMERIN-9 DERIVATIVES
    Publication number: 20230303647
    Abstract: The present invention relates to cyclic chemerin-9 derivatives of general formula (I) as described and defined herein, methods of preparing said peptides, and the use of said compounds for the treatment or prophylaxis of diseases, in particular cancer, diabetes, obesity and inflammatory disorders.
    Type: Application
    Filed: August 10, 2021
    Publication date: September 28, 2023
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jan Robert KRÄHLING, Bernd RIEDL, Annette BECK-SICKINGER, Tobias FISCHER, Anne CZERNIAK, Sylvia ELS-HEINDL
  • ADRENOMEDULLIN-ANALOGUES FOR LONG-TERM STABILIZATION AND THEIR USE
    Publication number: 20220387608
    Abstract: The invention relates to stabilized Adrenomedullin derivatives and use thereof. In particular, the invention relates to novel, biologically active, stabilized Adrenomedullin (ADM) compounds. The invention further relates to the compounds for use in a method for the treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders, and to medicaments comprising the compounds for treatment and/or prevention of cardiovascular, edematous and/or inflammatory disorders.
    Type: Application
    Filed: June 12, 2020
    Publication date: December 8, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Johannes KÖBBERLING, Donald BIERER, Ingo FLAMME, Bernd RIEDL, Lucas Hudson HOFMEISTER, Annette BECK-SICKINGER, Sylvia ELS-HEINDL, Jan-Patrick FISCHER, Eva-Maria JÜLKE
  • STABILIZATION ADRENOMEDULLIN DERIVATIVES AND USE THEREOF
    Publication number: 20180022780
    Abstract: The invention relates to novel, biologically active, stabilized Adrenomedullin (ADM) compounds. The invention further relates to the compounds for use in a method for the treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders, and to medicaments comprising the compounds for treatment and/or prevention of cardiovascular, edematous and/or inflammatory disorders.
    Type: Application
    Filed: September 24, 2015
    Publication date: January 25, 2018
    Inventors: Donald BIERER, Ingo FLAMME, Johannes KÖBBERLING, Bernd RIEDL, Annette BECK-SICKINGER, Ria SCHOENAUER, Jan-Patrick FISCHER
  • Substituted benzoxazoles
    Patent number: 9493472
    Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: November 15, 2016
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Swen Allerheiligen, Anja Buchmüller, Karen Engel, Christoph Gerdes, Kersten Matthias Gericke, Michael Gerisch, Stefan Heitmeier, Alexander Hillisch, Tom Kinzel, Philip Lienau, Bernd Riedl, Susanne Röhrig, Martina Victoria Schmidt, Julia Strassburger, Adrian Tersteegen
  • SUBSTITUTED BENZOXAZOLES
    Publication number: 20160137647
    Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.
    Type: Application
    Filed: May 30, 2014
    Publication date: May 19, 2016
    Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
  • SUBSTITUTED BENZOXAZOLES
    Publication number: 20160108027
    Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.
    Type: Application
    Filed: May 30, 2014
    Publication date: April 21, 2016
    Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
  • TRIAZOLOPYRIDINES AS THROMBIN INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES
    Publication number: 20160108039
    Abstract: The invention relates to substituted triazolopyridines and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.
    Type: Application
    Filed: June 2, 2014
    Publication date: April 21, 2016
    Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAFENIB
    Publication number: 20150328145
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof but without hydrophobic silica and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: December 21, 2013
    Publication date: November 19, 2015
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael BOTTGER, Georges VON DEGENFELD, Julia FREUNDLIEB, Claudia HIRTH-DIETRICH, Joerg KELDENICH, Jurgen KLAR, Uwe MUENSTER, Andreas OHM, Annett RICHTER, Bernd RIEDL
  • Aryl ureas as kinase inhibitors
    Patent number: 9181188
    Abstract: This invention relates to new aryl ureas and methods for their synthesis. The inventive compounds are useful in the treatment of (i) raf mediated diseases, for example, cancer, (ii) p38 mediated diseases such as inflammation and osteoporosis, and (iii) VEGF mediated diseases such as angiogenesis disorders.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: November 10, 2015
    Assignee: Bayer Healthcare LLC
    Inventors: Jacques Dumas, William J. Scott, Du-Schieng Chien, Ala Nassar, Wendy Lee, Susan Bjorge, Laszlo L. Musza, Bernd Riedl
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING SUNITINIB
    Publication number: 20150174096
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing sunitinib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 10, 2013
    Publication date: June 25, 2015
    Applicant: Bayer Healthcare LLC
    Inventors: Michael Bottger, Georges Von Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jurgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl, Joachim Telser
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING CEDIRANIB
    Publication number: 20150165028
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing cediranib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 10, 2013
    Publication date: June 18, 2015
    Applicant: Bayer Healthcare LLC
    Inventors: Michael Bottger, Georges Von Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jurgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl, Joachim Telser
  • Topical Ophthalmological Pharmaceutical Composition containing Axitinib
    Publication number: 20150164790
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing axitinib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 10, 2013
    Publication date: June 18, 2015
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael Böttger, Georges Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jürgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl, Joachim Telser
  • Topical Ophthalmological Pharmaceutical Composition containing Pazopanib
    Publication number: 20150141448
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing pazopanib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 10, 2013
    Publication date: May 21, 2015
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael Böttger, Georges Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jürgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl, Joachim Telser
  • OMEGA-CARBOXYARL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
    Publication number: 20140329866
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Application
    Filed: July 17, 2014
    Publication date: November 6, 2014
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Bernd RIEDL, Jacques DUMAS, Uday KHIRE, Timothy LOWINGER, William J. SCOTT, Roger A. SMITH, Jill E. WOOD
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAGENIB
    Publication number: 20140296301
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 26, 2012
    Publication date: October 2, 2014
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Michael Bottger, Georges Von Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jurgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl
  • Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
    Patent number: 8841330
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: September 23, 2014
    Assignee: Bayer Healthcare LLC
    Inventors: Bernd Riedl, Jacques Dumas, Uday Khire, Timothy B. Lowinger, William J. Scott, Roger A. Smith, Jill E. Wood
  • Topical Ophthalmological Pharmaceutical Composition containing Sorafenib
    Publication number: 20140235678
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing sorafenib or a pharmaceutically acceptable salt thereof or a polymorph, hydrate or solvate thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 26, 2012
    Publication date: August 21, 2014
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael Böttger, Julia Freundlieb, Claudia Hirth-Dietrich, Jürgen Klar, Uwe Muenster, Andreas Ohm, Bernd Riedl
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAFENIB
    Publication number: 20140179745
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof but without hydrophobic silica and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: December 16, 2013
    Publication date: June 26, 2014
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael BOTTGER, Georges VON DEGENFELD, Julia FREUNDLIEB, Claudia HIRTH-DIETRICH, Joerg KELDENICH, Jurgen KLAR, Uwe MUENSTER, Andreas OHM, Annett RICHTER, Bernd RIEDL
  • Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
    Patent number: 8637553
    Abstract: A compound of Formula (I): salts thereof, prodrugs thereof, metabolites thereof, pharmaceutical compositions containing such a compound, and use of such compound and compositions to treat diseases mediated by raf, VEGFR, PDGFR, p38 and flt-3.
    Type: Grant
    Filed: July 22, 2004
    Date of Patent: January 28, 2014
    Assignee: Bayer Healthcare LLC
    Inventors: Stephen Boyer, Jacques Dumas, Bernd Riedl, Scott Wilhelm
  • Substituted arylsulfonamides as antiviral agents
    Patent number: 8318761
    Abstract: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: November 27, 2012
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Niels Svenstrup, Holger Zimmermann, Dagmar Karthaus, Andreas Goeller, Dirk Heimbach, Kerstin Henninger, Dieter Lang, Daniela Paulsen, Bernd Riedl, Rudolf Schohe-Loop, Joachim Schuhmacher, Tobias Wunberg