Abstract: The wax product for treating or setting up a hairstyle or hairdo includes a composition containing at least one wax or wax-like substance, at least one non-volatile liquid hydrophobic oil and at least one volatile or easily volatilized hydrophobic substance that is a liquid or gas at room temperature. Because of the presence of the volatile substance in the composition a soft wax easily worked in the hair is obtained when the composition is applied to the hair. This soft wax hardens on the hair when the volatile ingredients evaporate. When the composition includes a propellant gas a wax with a larger surface area (wax snow) is produced, which is likewise easily worked into the hair and very effectively fixes or sets the hair.

Abstract: The wax composition for styling human hair provides hold, strength and rigidity, includes at least one wax and/or waxy material, and has a density of less than or equal to 0.9 g/ml, after being foamed in a fluid or softened state with a gas, preferably air or a non-reactive gas, such as nitrogen, so that it includes a bubble and/or pore structure. In the method for styling human hair this wax composition is applied to the hair and the hair is shaped with the wax composition applied to it.

Abstract: This invention relates to Benzopyranone Compounds, compositions comprising a Benzopyranone Compound and methods for treating or preventing cancer or inhibiting the growth of a cancer cell or neoplastic cell comprising administering an effective amount of a Benzopyranone Compound. The Benzopyranone Compounds have the formula: or a pharmaceutically acceptable salt thereof, wherein R1 is halogen, trifluoromethyl or C1-6 alkyl.

Abstract: An increase in the cutting hardness of a shaped body comprising a crystalline aluminosilicate is achieved by treating the shaped body with a gas comprising water vapor at from 100 to 600° C. and an absolute pressure of from 0.1 to 10 bar for a period of at least 20 hours, and this shaped body having an increased cutting hardness can be used in processes for chemical synthesis, in particular in a process for preparing triethylenediamine (TEDA) by reaction of ethylenediamine (EDA) and/or piperazine (PIP).

Abstract: Compositions and methods are provided for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38.

Abstract: A hair wax product is made by a process, in which a solid wax composition is heated to melt or soften it and then foamed with a gas in a mixer that applies shear energy to it. The gas is preferably air or a non-reactive gas, such as nitrogen. The gas is introduced to the liquified or softened solid wax composition in a sufficient amount so that the density of the resulting hair wax product is less than or equal to 0.9 g/ml, preferably 0.6 to 0.8 g/ml. The hair wax product contains bubbles and/or pores having a size of from 0.0001 to 5 mm and has melting and softening properties such that rubbing it by hand is sufficient to remove a waxy portion from it and work the waxy portion into hair.

Abstract: In the continuous process for preparing alkylamines by reacting C1-4-alkanols with ammonia in the gas phase in the presence of a shape-selective fixed-bed catalyst in a cooled reactor, the shape-selective fixed-bed catalyst is present in a single contiguous fixed bed in the reactor and tubes through which coolants are passed run within the fixed bed to regulate the temperature of the fixed bed.

Abstract: Compositions and methods are provided for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38.

Abstract: The present invention describes a process for the preparation of triethylenediamine by reacting piperazine over a zeolite catalyst which, in addition to SiO2, contains an oxide of at least one further divalent, trivalent or tetravalent metal M, wherein the zeolite has a molar Si/M ratio of >100. In particular, a zeolite of the ZSM-5 type is used. The use of the zeolites permits suppression of the undesired formation of the byproduct 2-ethylpiperazine and hence considerable simplification of the working-up, in combination with high piperazine conversions and a small excess of water.

Abstract: The emulsion-form hair treatment composition contains at least 50 percent by weight water; from 5 to 10 percent by weight of at least one hydrophobic substance, preferably a fatty alcohol, vegetable oil, hydrocarbon that is liquid at room temperature and/or silicone oil; at least 15 percent by weight of at least one emulsifier; a hair-fixing polymer, preferably at least one non-ionic and/or cationic vinyl lactam polymer, and an undissolved solid particulate, preferably silica. A method for setting up the hairstyle or hair-do involves applying this hair-treatment composition to dry or wet hair and then putting the hair the hairstyle or hair-do.

Abstract: The solid hair wax product for treating or setting up a human hair-do or hair style contains at least one silicone-free wax, at least one hydrophobic oil that is liquid at 25° C. and at least one silicone wax with a melting point in a range of from 20 to 45° C. Preferably the silicone-free wax is a hydrocarbon wax, the hydrophobic oil is a silicone oil and the silicone wax is an alkylmethyl-dimethyl-siloxane.

Abstract: A method is provided for manufacturing a function element carrier with function elements, for example, individual tufts made up of bristles and/or massage elements, interproximal cleaning elements, or other elements designed to be fastened to a toothbrush and also perform special functions. The function elements are equipped at their ends intended for anchoring in a toothbrush with an anchor, retainer or axle element. The method includes: (a) inserting several function elements in corresponding recesses of an injection mold, said injection mold being connected via grid or bar shaped channels formed in a die to recesses in the areas of the anchoring ends of the function elements; (b) filling the grid or bar shaped channels with liquefied plastic material and injecting said material at the anchoring ends of the function elements or embedding them therein; and (c) allowing the plastic material to cool and removing a function element carrier made up of a grid or bar shaped plastic frame and the function elements.

Abstract: The wax composition for styling human hair provides hold, strength and rigidity, includes at least one wax and/or waxy material, and has a density of less than or equal to 0.9 g/ml, after being foamed in a fluid or softened state with a gas, preferably air or a non-reactive gas, such as nitrogen, so that it includes a bubble and/or pore structure. In the method for styling human hair this wax composition is applied to the hair and the hair is shaped with the wax composition applied to it.

Abstract: Methods and apparatus for automated brush assembly are disclosed. A method of end-rounding bristle ends with an abrasive surface in random orbital motion relative to bristle tufts held in a movable gripper is described. A novel tuft carrier adapted to hold a plurality of bristle tufts in an arrangement suitable for direct mechanical insertion into the tuft chambers of a brush mold is also described. The tuft carrier has a plurality of tuft insertion cavities and a plurality of movable clamps, each clamp adapted to at least partially occlude one of the cavities when closed. Individual bristle tufts, having a fused end and a rounded or non-rounded bristle end, are transferred from a movable gripper to the tuft carrier by direct mechanical insertion. In addition, an apparatus for direct mechanical insertion of bristle tufts from a tuft carrier into the tuft chambers of a brush mold is described.

Abstract: A device for manufacturing brush products, in particular toothbrushes, with a bristle magazine having a feed chute for receiving filaments of precut length arranged in a dense array transverse to the longitudinal axis of the bristle magazine. The feed chute has a discharge opening which is bounded by a bristle picker closing the discharge opening from outside, and serves to feed filaments to a recess provided on the bristle picker. The recess receives only a predetermined quantity of filaments, combining them into tufts which are then transferred to further stations for further processing. According to the invention, the feed chute has a magazine bottom on which the discharge opening is formed. The magazine bottom is further shaped in an arcuate configuration tapering essentially in the direction of the discharge opening. This produces a steady filament flow in which dead zones are not allowed to develop.

Abstract: The present invention provides methods, compositions, and kits, for determining the effects of one or more candidate compounds on hot flash symptoms. In certain aspects, the methods, compositions, and kits can be used to identify compounds that decrease the incidence of hot flash symptoms. In other aspects, the methods, compositions, and kits can be used to determine whether candidate compounds increase the incidence of undesirable hot flash symptoms when administered to a subject.

Abstract: The invention is directed to a device for the manufacture of bristle products, in particular toothbrushes, with a feed unit for precut lengths of upstanding bristles arranged loosely in a supply duct, the bristles being routed directly to a picker segment picking up the bristles. The device includes a driven conveyor at the end of the supply duct close to the picker segment, or a further processing station.

Abstract: Compounds that modulate the estrogen receptor (ER) are disclosed, as well as pharmaceutical compositions containing the same. In a specific embodiment, the compounds are selective modulators for ER-? over ER-?. Methods are disclosed for modulating ER-? in cell and/or tissues expressing the same, including cells and/or tissue that preferentially express ER-?. More generally, methods for treating estrogen-related conditions are also disclosed, including conditions such as is breast cancer, testicular cancer, osteoporosis, endometriosis, cardiovascular disease, hypercholesterolemia, prostatic hypertrophy, prostatic carcinomas, obesity, hot flashes, skin effects, mood swings, memory loss, urinary incontinence, hairloss, cataracts, natural hormonal imbalances, and adverse reproductive effects associated with exposure to environmental chemicals.

Abstract: The present invention describes a process for the preparation of triethylenediamine by reacting piperazine over a zeolite catalyst which, in addition to SiO2, contains an oxide of at least one further divalent, trivalent or tetravalent metal M, wherein the zeolite has a molar Si/M ratio of >100. In particular, a zeolite of the ZSM-5 type is used. The use of the zeolites permits suppression of the undesired formation of the byproduct 2-ethylpiperazine and hence considerable simplification of the working-up, in combination with high piperazine conversions and a small excess of water.

Abstract: Compositions and methods are provided for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38.