Patents by Inventor Bernd Sundermann

Bernd Sundermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF A MIXTURE OF MODIFIED GLUCOSE POLYMERS FOR REDUCING TUMOR METASTASIS
    Publication number: 20180021367
    Abstract: Disclosed herein is a solution, in particular a pharmaceutically acceptable solution, comprising icodextrin and hydroxyalkyl starch (HAS) that can be used in methods of preventing metastasis formation and/or relapse by administration to a body cavity of a subject afflicted with cancer. Also disclosed is a kit comprising icodextrin and HAS in pre-weighed amounts and a pharmaceutically acceptable means of dissolving the same. Also disclosed is a device comprising a pharmaceutically acceptable solution and means for administering the same.
    Type: Application
    Filed: February 1, 2016
    Publication date: January 25, 2018
    Inventors: Bernd Sundermann, Lars Walz, Silke Baasner, Frank Nocken, Christoph Meyer
  • Process or preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds
    Patent number: 9862719
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and methods of using them.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: January 9, 2018
    Assignee: Gruenenthal GmbH
    Inventors: Claudia Hinze, Otto Aulenbacher, Bernd Sundermann, Stefan Oberboersch, Elmar Friderichs, Werner Englberger, Babette-Yvonne Koegel, Klaus Linz, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, Valerie Sarah Rose, Michael Jonathan Lipkin
  • POLYSACCHARIDE FOR USE IN PREVENTING METASTASIS FORMATION AND/OR RELAPSE
    Publication number: 20160175340
    Abstract: The present invention relates to a polysaccharide comprising, optionally substituted, monosaccharide units linked via alpha-glycosidic bonds for use in preventing metastasis formation and/or relapse by administration to a body cavity of a subject afflicted with cancer. The present invention further relates to a method for preventing metastasis formation in a subject afflicted with cancer, comprising administering said composition to a body cavity of said subject, and thereby preventing metastasis formation in said subject. The present invention also relates to a composition and to a kit comprising a polysaccharide and a pharmaceutically acceptable means of solubilizing the same and to a device comprising a polysaccharide and means for administering the same.
    Type: Application
    Filed: July 25, 2014
    Publication date: June 23, 2016
    Inventors: Bernd Sundermann, Lars Walz, Silke Baasner, Frank Nocken, Christoph Meyer
  • Substituted indole derivatives
    Patent number: 9206156
    Abstract: Substituted indole derivatives, processes for the preparation thereof, medicinal products and pharmaceutical compositions containing these compounds and the use of substituted indole derivatives to treat pain and other conditions and for other medical purposes.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: December 8, 2015
    Assignee: GRÜNENTHAL GMBH
    Inventors: Stefan Schunk, Stefan Oberbörsch, Werner Englberger, Bernd Sundermann
  • Process for Preparing Spirocyclic Cyclohexane Compounds, Compositions Containing Such Compounds and Method of Using Such Compounds
    Publication number: 20150322080
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and methods of using them.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 12, 2015
    Inventors: Claudia HINZE, Otto AULENBACHER, Bernd SUNDERMANN, Stefan OBERBOERSCH, Elmar FRIDERICHS, Werner ENGLBERGER, Babette-Yvonne KOEGEL, Klaus LINZ, Hans SCHICK, Helmut SONNENSCHEIN, Birgitta HENKEL, Valerie Sarah ROSE, Michael Jonathan LIPKIN
  • Process for preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds
    Patent number: 9120797
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and methods of using them.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: September 1, 2015
    Assignee: Gruenenthal GmbH
    Inventors: Claudia Hinze, Otto Aulenbacher, Bernd Sundermann, Stefan Oberboersch, Elmar Friderichs, Werner Englberger, Babette-Yvonne Koegel, Klaus Linz, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, Valerie Sarah Rose, Michael Jonathan Lipkin
  • Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions
    Patent number: 8791268
    Abstract: Vanilloid receptor ligand compounds corresponding to formula I: a process for producing such compounds, pharmaceutical compositions containing them, and the use of such compounds to treat pain and various other vanilloid receptor mediated conditions.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: July 29, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek Saunders, Michael Przewosny, Bernd Sundermann, Jeewoo Lee
  • Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof to treat pain and other conditions
    Patent number: 8785474
    Abstract: Vanilloid receptor ligand compounds corresponding to formula I: pharmaceutical compositions containing such compounds, a process for producing such compounds, and methods of using such compounds for treating or inhibiting pain and various other disorders or conditions.
    Type: Grant
    Filed: August 16, 2011
    Date of Patent: July 22, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek Saunders, Bernd Sundermann, Jeewoo Lee
  • Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations
    Publication number: 20140179686
    Abstract: The present invention relates to novel vanilloid receptor ligands, to a process for the production thereof, to pharmaceutical preparations containing these compounds and to the use of these compounds for the production of pharmaceutical preparations.
    Type: Application
    Filed: February 25, 2014
    Publication date: June 26, 2014
    Applicant: Gruenenthal GmbH
    Inventors: Jeewoo LEE, Hyung Chul Ryu, Robert FRANK, Gregor BAHRENBERG, Jean DE VRY, Thomas CHRISTOPH, Derek John SAUNDERS, Klaus SCHIENE, Bernd SUNDERMANN
  • Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions
    Patent number: 8735426
    Abstract: Compounds corresponding to formula I: which act as vanilloid receptor ligands, pharmaceutical compositions containing such compounds, a process for the producing such compounds, and the use thereof to treat or inhibit pain and/or various other disorders or conditions.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: May 27, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek Saunders, Bernd Sundermann, Jeewoo Lee
  • Vanilloid receptor ligands and use thereof for the production of pharmaceutical preparations
    Patent number: 8710233
    Abstract: The present invention relates to novel vanilloid receptor ligands, to a process for the production thereof, to pharmaceutical preparations containing these compounds and to the use of these compounds for the production of pharmaceutical preparations.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: April 29, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Jeewoo Lee, Hyung Chul Ryu, Robert Frank, Gregor Bahrenberg, Jean De Vry, Thomas Christoph, Derek John Saunders, Klaus Schiene, Bernd Sundermann
  • Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions
    Patent number: 8642775
    Abstract: Vanilloid receptor ligand compounds corresponding to formula I: a process for producing such compounds, pharmaceutical compositions containing them, and the use of such compounds to treat pain and various other vanilloid receptor mediated conditions.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: February 4, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek Saunders, Michael Przewosny, Bernd Sundermann, Jewoo Lee
  • Substituted 1-oxa-2,8-diaza-spiro [4,5] dec-2-ene derivatives and related treatment methods
    Patent number: 8557796
    Abstract: Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene compounds and processes for their production, the use thereof for producing pharmaceutical compositions, pharmaceutical compositions containing these compounds and methods of treatment using these compounds.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: October 15, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Heinrich Helmut Buschmann, Guenter Werner Englberger, Tieno Germann, Hagen-Henrich Hennies, Corinna Maul, Bernd Sundermann, Joerg Holenz
  • Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines for use in treating pain, depression and/or anxiety
    Patent number: 8278338
    Abstract: Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines=compounds corresponding to formula (I), wherein the various substituents have the meaning provided in the description, and pharmaceutical formulations containing these compounds and methods for producing these compounds and related pharmaceutical formulation, and to methods for treating or inhibiting pain, depression and/or anxiety states.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: October 2, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Bernd Sundermann, Hagen-Heinrich Hennies, Klaus Schiene, Petra Bloms-Funke, Werner Englberger, Sven Frormann, Derek Saunders
  • Substituted cyclic urea derivatives and the use thereof as vanilloid receptor 1 modulators
    Patent number: 8207182
    Abstract: The present invention relates to substituted cyclic urea derivatives corresponding to formula I, to processes for the preparation thereof, to medicinal drugs containing such compounds, to the use of such compounds in the preparation of medicinal drugs and in related treatment methods.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: June 26, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Bernd Sundermann, Hans Schick, Helmut Sonnenschein
  • Substituted 1-oxa-3,8-diazaspiro[4.5]-decan-2-one-compounds and the use thereof for producing drugs
    Patent number: 8153795
    Abstract: The present invention relates to substituted 1-oxa-3,8-diazaspiro[4.5]-decan-2-one compounds, to methods for the production thereof, to medicaments containing these compounds and to the use of these compounds for producing medicaments.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: April 10, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Corinna Sundermann, Michael Przewosny, Bernd Sundermann
  • Spirocyclic cyclohexane compounds with analgesic activity
    Patent number: 8124788
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a process for manufacturing such compounds, pharmaceutical compositions that contain such compounds, and the use of such spirocyclic cyclohexane compounds for the production of pharmaceuticals, and particularly for the treatment of pain.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: February 28, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Stefan Oberboersch, Bernd Sundermann, Werner Englberger, Hagen-Heinrich Hennies, Babette-Yvonne Koegel, Stephan Schunk, Heinz Graubaum
  • Substituted sulfonamide compounds
    Patent number: 8119633
    Abstract: Substituted sulfonamide compounds corresponding to formula I pharmaceutical compositions comprising them, a process for preparing them, and the use of such compounds to treat or inhibit pain and other disorders or disease states.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: February 21, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Werner Englberger, Timo Struenker, Ruth Jostock, Sabine Hees, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Substituted amide compounds
    Patent number: 8106055
    Abstract: Substituted amide compounds corresponding to formula I: processes for preparing them, pharmaceutical compositions containing these compounds, and the use of substituted amide derivatives for the preparation of medicaments for the treatment of pain and various other conditions.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: January 31, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Utz-Peter Jagusch, Beatrix Merla, Stefan Schunk, Werner Englberger, Timo Struenker, Hagen-Heinrich Hennies, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Heteroaryl substituted cyclohexyl-1,4-diamine compounds
    Patent number: 8093272
    Abstract: Novel cyclohexyl-1,4-diamine compounds corresponding to formula I, processes for the production thereof, pharmaceutical compositions containing these compounds, methods of producing pharmaceutical compositions including these compounds and related methods of treating or inhibiting certain diseases or conditions.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: January 10, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Corinna Sundermann, Bernd Sundermann