Patents by Inventor Bernhard Erb

Bernhard Erb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzothiazolone compound
    Patent number: 10251868
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: April 9, 2019
    Assignee: NOVARTIS AG
    Inventors: Jun Cao, Bernhard Erb, Robin Alec Fairhurst, Arnaud Grandeury, Shinji Hatakeyama, Magdalena Koziczak-Holbro, Xinzhong Lai, Philipp Lustenberger, Bernd Ulrich Riebesehl, Nicola Tufilli, Thomas Ullrich, Xiang Wu, Jianguang Zhou
  • Synthesis of 2-carboxamide cycloamino urea derivatives
    Patent number: 10059670
    Abstract: Provided herein are processes and intermediate compounds useful for the preparation of 2-carboxamide cycloamino urea derivatives, and useful intermediates therefore.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: August 28, 2018
    Assignee: Novartis AG
    Inventors: Bernhard Erb, Isabelle Sylvie Gallou, Florian Karl Kleinbeck-Riniker
  • BENZOTHIAZOLONE COMPOUND
    Publication number: 20180140582
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Application
    Filed: January 22, 2018
    Publication date: May 24, 2018
    Applicant: NOVARTIS AG
    Inventors: Jun CAO, Bernhard ERB, Robin Alec FAIRHURST, Arnaud GRANDEURY, Shinji HATAKEYAMA, Magdalena KOZICZAK-HOLBRO, Xinzhong LAI, Philipp LUSTENBERGER, Bernd Ulrich RIEBESEHL, Nicola TUFILLI, Thomas ULLRICH, Xiang WU, Jianguang ZHOU
  • Benzothiazolone compound
    Patent number: 9913828
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: March 13, 2018
    Assignee: NOVARTIS AG
    Inventors: Jun Cao, Bernhard Erb, Robin Alec Fairhurst, Arnaud Grandeury, Shinji Hatakeyama, Magdalena Koziczak-Holbro, Xinzhong Lai, Philipp Lustenberger, Bernd Ulrich Riebesehl, Nicola Tufilli, Thomas Ullrich, Xiang Wu, Jianguang Zhou
  • SYNTHESIS OF 2-CARBOXAMIDE CYCLOAMINO UREA DERIVATIVES
    Publication number: 20170355677
    Abstract: Provided herein are processes and intermediate compounds useful for the preparation of 2-carboxamide cycloamino urea derivatives, and useful intermediates therefore.
    Type: Application
    Filed: August 23, 2017
    Publication date: December 14, 2017
    Applicant: NOVARTIS AG
    Inventors: Bernhard Erb, Isabelle Sylvie Gallou, Florian Karl Kleinbeck-Riniker
  • Synthesis of 2-carboxamide cycloamino urea derivatives
    Patent number: 9776966
    Abstract: Provided herein are processes and intermediate compounds useful for the preparation of 2-carboxamide cycloamino urea derivatives, and useful intermediates therefore.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: October 3, 2017
    Assignee: Novartis AG
    Inventors: Bernhard Erb, Isabelle Sylvie Gallou, Florian Karl Kleinbeck
  • Synthesis of 2-carboxamide cycloamino urea derivatives
    Publication number: 20170240509
    Abstract: Provided herein are processes and intermediate compounds useful for the preparation of 2-carboxamide cycloamino urea derivatives, and useful intermediates therefore.
    Type: Application
    Filed: April 6, 2017
    Publication date: August 24, 2017
    Inventors: Bernhard Erb, Isabelle Sylvie Gallou, Florian Karl Kleinbeck
  • Synthesis of 2-carboxamide cycloamino urea derivatives
    Patent number: 9650373
    Abstract: Provided herein are processes useful for the preparation of 2-carboxamide cycloamino urea derivatives of formula (X), and useful intermediates therefore, at internal temperatures such as less than about ?5° C. to about ?15° C. and using solvents such as tetrahydrofuran, bases such as amines, and the like.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: May 16, 2017
    Assignee: Novartis AG
    Inventors: Bernhard Erb, Isabelle Sylvie Gallou, Florian Karl Kleinbeck
  • BENZOTHIAZOLONE COMPOUND
    Publication number: 20160279107
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Application
    Filed: June 10, 2016
    Publication date: September 29, 2016
    Applicant: NOVARTIS AG
    Inventors: Jun CAO, Bernhard ERB, Robin Alec FAIRHURST, Arnaud GRANDEURY, Shinji HATAKEYAMA, Magdalena KOZICZAK-HOLBRO, Xinzhong LAI, Philipp LUSTENBERGER, Bernd Ulrich RIEBESEHL, Nicola TUFILLI, Thomas ULLRICH, Xiang Wu, Jianguang ZHOU
  • BENZOTHIAZOLONE COMPOUND
    Publication number: 20160075670
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Application
    Filed: November 20, 2015
    Publication date: March 17, 2016
    Applicant: NOVARTIS AG
    Inventors: Jun CAO, Bernhard ERB, Robin Alec FAIRHURST, Arnaud GRANDEURY, Shinji HATAKEYAMA, Magdalena KOZICZAK-HOLBRO, Philipp LUSTENBERGER, Bernd RIEBESEHL, Nicola TUFILLI, Thomas ULLRICH, Xiang WU, Jianguang ZHOU
  • BENZOTHIAZOLONE COMPOUND
    Publication number: 20150336914
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Application
    Filed: August 3, 2015
    Publication date: November 26, 2015
    Applicant: NOVARTIS AG
    Inventors: Jun CAO, Bernhard ERB, Robin Alec FAIRHURST, Arnaud GRANDEURY, Shinji HATAKEYAMA, Magdalena KOZICZAK-HOLBRO, Philipp LUSTENBERGER, Bernd RIEBESEHL, Nicola TUFILLI, Thomas ULLRICH, Xiang WU, Jianguang ZHOU
  • BENZOTHIAZOLONE COMPOUND
    Publication number: 20150094346
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Application
    Filed: December 10, 2014
    Publication date: April 2, 2015
    Applicant: NOVARTIS AG
    Inventors: Jun CAO, Bernhard ERB, Robin Alec FAIRHURST, Arnaud GRANDEURY, Shinji HATAKEYAMA, Magdalena KOZICZAK-HOLBRO, Philipp LUSTENBERGER, Bernd RIEBESEHL, Nicola TUFILLI, Thomas ULLRICH, Xiang WU, Jianguang ZHOU
  • Benzothiazolone compound
    Patent number: 8933108
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Grant
    Filed: September 5, 2012
    Date of Patent: January 13, 2015
    Assignee: Novartis AG
    Inventors: Jun Cao, Bernhard Erb, Robin Alec Fairhurst, Arnaud Grandeury, Shinji Hatakeyama, Magdalena Koziczak-Holbro, Xinzhong Lai, Philipp Lustenberger, Bernd Riebesehl, Nicola Tufilli, Thomas Ullrich, Xiang Wu, Jianguang Zhou
  • Synthesis of 2-carboxamide cycloamino urea derivatives
    Publication number: 20130331579
    Abstract: Provided herein are processes and intermediate compounds useful for the preparation of 2-carboxamide cycloamino urea derivatives, and useful intermediates therefore.
    Type: Application
    Filed: March 1, 2012
    Publication date: December 12, 2013
    Inventors: Bernhard Erb, Isabelle Sylvie Gallou, Florian Karl Kleinbeck
  • BENZOTHIAZOLONE COMPOUND
    Publication number: 20130245080
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Application
    Filed: September 5, 2012
    Publication date: September 19, 2013
    Applicant: NOVARTIS AG
    Inventors: Jun CAO, Bernhard ERB, Robin Alec FAIRHURST, Arnaud GRANDEURY, Shinji HATAKEYAMA, Magdalena KOZICZAK-HOLBRO, Xinzhong LAI, Philipp LUSTENBERGER, Bernd RIEBESEHL, Nicola TUFILLI, Thomas ULLRICH, Xiang WU, Jianguang ZHOU
  • Method of operating a gas turbine power plant
    Patent number: 8291713
    Abstract: In a method of operating a gas turbine during shut down, the gas turbine is decelerated and closure of compressor inlet guide vanes (1) is initiated at a shaft speed at least 5% above the shaft speed where a vibration peak occurs. The compressor inlet guide vanes (1) are closed by an angle in the range from 15°-35°, preferably at a rate between 5° and 10° per second. The method effects a reduction of the risk of rotational stall.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: October 23, 2012
    Assignee: ALSTOM Technology Ltd.
    Inventors: Charles Matz, Bernhard Erb, Bikas Das Burma, Luca Beresini, Martin Heinrich Treiber, Peter Marx
  • Process for the synthesis of organic compounds
    Patent number: 8008504
    Abstract: The present invention provides an efficient, safe and cost effective way to prepare 5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine which is a key intermediate for the preparation of substituted pyrimidinylaminobenzamides of formula (II):
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: August 30, 2011
    Assignee: Novartis AG
    Inventors: Stephan Abel, Murat Acemoglu, Bernhard Erb, Christoph Krell, Joseph Sclafani, Mark Meisenbach, Mahavir Prashad, Wen-Chung Shieh, Song Xue
  • PROCESS FOR THE SYNTHESIS OF ORGANIC COMPOUNDS
    Publication number: 20100280257
    Abstract: The present invention provides an efficient, safe and cost effective way to prepare 5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine which is a key intermediate for the preparation of substituted pyrimidinylaminobenzamides of formula (II):
    Type: Application
    Filed: July 12, 2010
    Publication date: November 4, 2010
    Inventors: Stephan Abel, Murat Acemoglu, Bernhard Erb, Christoph Krell, Joseph Sclafani, Mark Meisenbach, Mahavir Prashad, Wen-Chung Shieh, Song Xue
  • Process for the synthesis of organic compounds
    Patent number: 7781597
    Abstract: The present invention provides an efficient, safe and cost effective way to prepare 5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine which is a key intermediate for the preparation of substituted pyrimidinylaminobenzamides of formula (II):
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: August 24, 2010
    Assignee: Novartis AG
    Inventors: Stephan Abel, Murat Acemoglu, Bernhard Erb, Christoph Krell, Joseph Sclafani, Mark Meisenbach, Mahavir Prashad, Wen-Chung Shieh, Song Xue
  • METHOD OF OPERATING A GAS TURBINE POWER PLANT
    Publication number: 20090071165
    Abstract: In a method of operating a gas turbine during shut down, the gas turbine is decelerated and closure of compressor inlet guide vanes (1) is initiated at a shaft speed at least 5% above the shaft speed where a vibration peak occurs. The compressor inlet guide vanes (1) are closed by an angle in the range from 15°-35°, preferably at a rate between 5° and 10° per second. The method effects a reduction of the risk of rotational stall.
    Type: Application
    Filed: September 26, 2008
    Publication date: March 19, 2009
    Inventors: Charles Matz, Bernhard Erb, Bikas Das Burma, Luca Beresini, Martin Heinrich Treiber, Peter Marx