Patents by Inventor Bernhard Kubanek

Bernhard Kubanek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human monoclonal antibody against hepatitis C virus E2 glycoprotein
    Patent number: 7241445
    Abstract: Disclosed is a hybridoma cell line which produces human antibodies capable of binding to the hepatitis C virus (HCV) E2 glycoprotein and capable of neutralizing HCV infection in vivo in an animal model, as well as antibodies produced by the cell line. Also disclosed are various uses of said antibodies in the prevention and treatment of HCV infection. Peripheral blood lymphocytes obtained from human donors having a high titer of anti HCV E2 antibodies are transformed in vitro by Epstein-Barr virus and then fused with heteromyeloma cells to generate hybridomas secreting human antibodies having a high affinity and specificity to HCV E2 glycoprotein.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: July 10, 2007
    Assignee: DRK-Blutspendedienst Baden-Wurttemberg
    Inventors: Bernhard Kubanek, Marcia Da Silva Cardoso, Karl Sifmoneit, Shlomo Dagan, Rachel Eren