Patents by Inventor Bernhard .O slashed.. Palsson

Bernhard .O slashed.. Palsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of increasing rates of infection by directing motion of vectors
    Patent number: 5866400
    Abstract: This invention provides methods of increasing the frequency of contact between vectors and stationary target cells in an apparatus containing them which involves causing the vectors to move towards the target cells with motion above and beyond random Brownian motion. The methods of this invention include causing the vectors to move in the direction of the cells by (1) causing flow-through of a liquid containing the vectors through or past a cell bed, (2) moving charged vectors towards the target cells by electrodiffusion and (3) centrifuging vectors and cells to cause settling of vectors onto the cells.
    Type: Grant
    Filed: March 21, 1997
    Date of Patent: February 2, 1999
    Assignee: The University of Michigan
    Inventors: Bernhard .O slashed. Palsson, Michael F. Clarke, Alice S.Y. Chuck
  • Methods, compositions and apparatus for cell transfection
    Patent number: 5811274
    Abstract: This invention provides methods, compositions and apparatus for increasing the transfection efficiency of target cells by particles, especially retroviral particles, compared with that achieved by current methods. The transfection method comprises depositing the particles on a cell growth support and contacting target cells with the particle-loaded cell growth support.
    Type: Grant
    Filed: December 9, 1994
    Date of Patent: September 22, 1998
    Assignee: The Regents of the University of Michigan
    Inventor: Bernhard .O slashed.. Palsson
  • Method, compositions and apparatus for cell transfection
    Patent number: 5804431
    Abstract: This invention provides methods, compositions and apparatus for increasing the transfection efficiency of target cells by particles, especially retroviral particles, compared with that achieved by current methods. The transfection method comprises depositing the particles on a cell growth support and contacting target cells with the particle-loaded cell growth support.
    Type: Grant
    Filed: March 13, 1997
    Date of Patent: September 8, 1998
    Assignee: The Regents of The University of Michigan
    Inventor: Bernhard .O slashed.. Palsson
  • Methods of increasing rates of infection by directing motion of vectors
    Patent number: 5672494
    Abstract: This invention provides methods of increasing the frequency of contact between vectors and stationary target cells in an apparatus containing them which involves causing the vectors to move towards the target cells with motion above and beyond random Brownian motion. The methods of this invention include causing the vectors to move in the direction of the cells by (1) causing flow-through of a liquid containing the vectors through or past a cell bed, (2) moving charged vectors towards the target cells by electrodiffusion and (3) centrifuging vectors and cells to cause settling of vectors onto the cells.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 30, 1997
    Assignee: The University of Michigan
    Inventors: Bernhard .O slashed.. Palsson, Michael F. Clarke, Alice S. Y. Chuck
  • Methods, compositions and apparatus for cell transfection
    Patent number: 5654185
    Abstract: This invention provides methods, compositions and apparatus for increasing the transfection efficiency of target cells by particles, especially retroviral particles, compared with that achieved by current methods. The transfection method comprises depositing the particles on a cell growth support and contacting target cells with the particle-loaded cell growth support.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 5, 1997
    Assignee: The Regents of the University of Michigan
    Inventor: Bernhard .O slashed.. Palsson