Abstract: The present invention describes compounds modulating the function of mitochondrial complex I (NADH-quinone oxidoreductase) having formula (I)

Abstract: dsRNAi oligonucleotides can be used in methods for the treatment of NASH, preferably the advanced fibrotic and/or cirrhotic stages thereof, using dosage regimens comprising a loading phase followed by a maintenance phase.

Abstract: A method of forming a dental restoration for a tooth having an outer surface includes acquiring a first three-dimensional representation representative of the outer surface of the tooth; generating a design of a first part of the dental restoration based on the first three-dimensional representation of the tooth; forming the first part of the dental restoration; preparing the tooth to form a prepared tooth while forming the first part of the dental restoration; obtaining a second three-dimensional representation of the prepared tooth; generating a design of a second part of the dental restoration based on at least the second three-dimensional representation of the prepared tooth; merging the design of the second part of the dental restoration to the first part of the dental restoration; and forming the second part of the dental restoration.

Abstract: Various embodiments include an electrolysis cell comprising: a cathode space housing a cathode; a first ion exchange membrane including an anion exchanger and adjoining the cathode space; an anode space housing an anode; a second ion exchange membrane including a cation exchanger and adjoining the anode space; and a salt bridge space disposed between the first ion exchange membrane and the second ion exchange membrane. The cathode comprises: a gas diffusion electrode having a porous bound catalyst structure of a particulate catalyst on a support; a coating of a particulate catalyst on the first and/or second ion exchange membrane; and a porous conductive support impregnated with a catalyst.

Abstract: An electrode, which includes at least one tetragonally crystallized compound containing at least one element selected from the group of Cu and Ag, the crystal lattice of the compound being of the space group I41/amd type. An electrolysis cell includes the electrode.

Abstract: A support apparatus includes a gas-fillable support that is connectable to a gas generator. The gas-fillable support is securable to a body of a motor vehicle and has a first operating state which exists before the gas generator is activated and which has a first volume. The gas-fillable support has a second operating state which exists after the gas generator is activated and which has a second volume which is greater than the first volume. The gas-fillable support in the second operating state is contactable against a first portion which is operationally connected to the body and is contactable against a second portion which is operationally connected to the body and which is remote from the first end portion. A first mechanical strength of the gas-fillable support in the first operating state is less than a second mechanical strength of the gas-fillable support in the second operating state.

Abstract: The present invention describes compounds modulating the function of mitochondrial complex I (NADH-quinone oxidoreductase) having formula (I)

Abstract: A shading device includes a shading curtain and a drawing device. The shading curtain includes a first and second shading layer that have at least two types of light transmission areas with different light transmission properties. The drawing device includes a first and second drawing member. The first drawing member is connected with the first shading layer and is configured to draw the first shading layer. The second drawing member is connected with the second shading layer and is configured to draw the second shading layer. The first and second drawing members are movable relative to each other between a first relative position and a second relative position. The first and the second shading layers parallelly move relative to each other. In the first relative position, the shading curtain has a first light transmission property, and in the second relative position, the shading curtain has a second light transmission property.

Abstract: A method produces a vehicle replacement part for a first vehicle component of a connecting system, which is fixed to a second vehicle component via a detachable clip connection. The first vehicle component has a male fixing element, and the second vehicle component has a female fixing element. To connect the first vehicle component to the second vehicle component, the male fixing element is plugged into the female fixing element and is latched. The production method of the vehicle replacement part provides an unfinished part, which is dimensioned to produce the vehicle replacement part. Then, the unfinished part is reshaped in accordance with the geometry of the first vehicle component. Male fixing elements are then provided and, in the last step, the male fixing elements are joined to the reshaped unfinished part.

Abstract: A body-adaptable arm rest arrangement includes an arm rest having an actuation unit for adjusting different arm rest positions, and a base. The arm rest is connected to the base via the actuation unit.

Abstract: A storage compartment for installation in a motor vehicle includes a storage volume which is bounded laterally by an at least partially encircling storage wall. At least one elastic compartment divider, which has a macroscopically elastic material at least in a central region of a longitudinal extent of the compartment divider, is provided such that the compartment divider can be transferred between a first divider position and a second divider position and which, at the first divider position, divides the storage volume into a first partial compartment and a second partial compartment and, at the second divider position, forms part of the storage wall of the storage volume. Two spaced-apart divider receptacles are arranged on the storage wall and at which in each case one of two longitudinal ends of the compartment divider is accommodated. The compartment divider is mounted on each of the divider receptacles so as to be rotatable about a divider longitudinal axis.

Abstract: An apparatus ventilates the passenger compartment of a motor vehicle. The apparatus has a source for producing an open or free jet of moving air, and a deflecting body, wherein the deflecting body is spaced apart from the source and one of the surfaces of the deflecting body is, according to the designated use, an impact face against which the open jet impinges, and the impact face is a deformable face which is integrated steplessly into a surrounding surface.

Abstract: A motor vehicle with a vehicle interior includes a dashboard arranged in front of at least one front seat. A storage device is movable in a reversible manner, by way of a movement mechanism, from a not-in-use position in the dashboard into a use position in front of the front seat. The storage device is arrested at least in the use position. In the use position, the storage device has a carrying structure made up of two laterally arranged, inflated supporting elements. An approximately horizontally oriented table top is arranged on the two supporting elements.

Abstract: A vehicle has a display screen designed to be moved between an observation position and a reflection position. The display screen has a display screen surface, wherein, when in the observation position, the display screen surface can be directly observed by a user of the vehicle from a user position of the vehicle. The vehicle has a reflecting surface, wherein, in the reflecting position, the display screen surface faces the reflecting surface such that an image displayed on the display screen surface generates a mirror image on the reflecting surface, which mirror image is visible to a user of the vehicle from the user position of the vehicle.

Abstract: A support apparatus includes a gas-fillable support that is connectable to a gas generator. The gas-fillable support is securable to a body of a motor vehicle and has a first operating state which exists before the gas generator is activated and which has a first volume. The gas-fillable support has a second operating state which exists after the gas generator is activated and which has a second volume which is greater than the first volume. The gas-fillable support in the second operating state is contactable against a first portion which is operationally connected to the body and is contactable against a second portion which is operationally connected to the body and which is remote from the first end portion. A first mechanical strength of the gas-fillable support in the first operating state is less than a second mechanical strength of the gas-fillable support in the second operating state.

Abstract: A molded part, in particular to an interior trim part of a motor vehicle, consists of a pressed carrier, formed from a fiber-plastic composite, a carrier structure made of a plastic for fixedly arranging the molded part on a motor vehicle, and a light source. The carrier structure is molded with an injection molding method to a surface of a rear side of the pressed carrier such that the carrier structure lies flat directly against the surface, in particular the entire surface, of the rear side of the pressed carrier. The pressed carrier is at least translucent, and the carrier structure is opaque. The carrier structure has at least one cutout, which forms a through opening to the surface of the pressed carrier. The light source is arranged for backlighting purposes on the rear side of the pressed carrier such that, with appropriate use, light is visible on a viewing side of the pressed carrier.

Abstract: An air outlet device for feeding air into a vehicle interior in a directionally controlled manner is provided. The air outlet device has an air channel, a first pivotable air-guiding element, and a second pivotable air-guiding element. The first air-guiding element and the second air-guiding element, together with an air outlet opening, form an air outlet nozzle. The first air-guiding element and the second air-guiding element are configured to be not pivotable in the same direction.

Abstract: A method for producing sensor information depends on a rotational speed, using a rotational speed sensor which is adapted to output rotational speed pulses in predetermined angular positions of a physical sensor field that rotates at the rotational speed. In order to increase resolution, a digital angle signal each is determined between the pulses. A defined number of most significant bits of said angle information is output to determine the rotational speed so that the interval between two pulses is subdivided into a defined number of subintervals. An angle value which can be unambiguously interpreted by means of the sinusoidal signal can be determined from the cosine signal by using two phase shift sinusoidal signals and an arccos function. The device optionally outputs the angle signal below a threshold value and an impulse signal above the threshold value to determine speed.

Abstract: A process for producing ammonia and an apparatus for producing ammonia are disclosed herein. The process includes: the electrolytic production of a metal at a cathode of an electrolysis cell, wherein the metal is selected from Li, Mg, Ca, Sr, Ba, Zn, Al and/or alloys and/or mixtures thereof; production of a nitride of the metal M by reaction of the electrolytically produced metal with a gas including nitrogen; introduction of the nitride of the metal M into the electrolysis cell (e.g., into an anode chamber of the electrolysis cell); and reaction of the nitride of the metal M at an anode of the electrolysis cell to produce ammonia.

Abstract: A method for producing phosgene directly from the directly combined raw products, preferably only dried raw products, of a combined CO2 chloride electrolysis. A first gaseous product of CO is produced from CO2 on the cathode side in at least one electrolysis cell for a CO2 conversion into CO, and a second gaseous product of at least Cl2 is produced from HCl and/or a metal chloride on the anode side, wherein phosgene is produced from the gaseous products.