Patents by Inventor Bernice Yeung

Bernice Yeung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FIBRONECTIN BASED SCAFFOLD PROTEINS HAVING IMPROVED STABILITY
    Publication number: 20220119495
    Abstract: The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
    Type: Application
    Filed: September 29, 2021
    Publication date: April 21, 2022
    Inventors: Ray CAMPHAUSEN, John O'LOUGHLIN, Bernice YEUNG, Yihong ZHANG
  • Fibronectin based scaffold proteins having improved stability
    Patent number: 11161893
    Abstract: The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: November 2, 2021
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Ray Camphausen, John O'Loughlin, Bernice Yeung, Yihong Zhang
  • Methods for maintaining pegylation of polypeptides
    Patent number: 10898538
    Abstract: Described herein are methods for maintaining PEGylation and inhibiting dePEGylation of polypeptides, such as fibronectin-based scaffold proteins, during storage.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: January 26, 2021
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Bernice Yeung, Jack Wang
  • FIBRONECTIN BASED SCAFFOLD PROTEINS HAVING IMPROVED STABILITY
    Publication number: 20190263892
    Abstract: The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
    Type: Application
    Filed: March 11, 2019
    Publication date: August 29, 2019
    Inventors: Ray Camphausen, John O'Loughlin, Bernice Yeung, Yihong Zhang
  • Fibronectin based scaffold proteins having improved stability
    Patent number: 10273286
    Abstract: The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: April 30, 2019
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Ray Camphausen, John O'Loughlin, Bernice Yeung, Yihong Zhang
  • FIBRONECTIN BASED SCAFFOLD PROTEINS HAVING IMPROVED STABILITY
    Publication number: 20170166627
    Abstract: The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
    Type: Application
    Filed: December 20, 2016
    Publication date: June 15, 2017
    Inventors: Ray CAMPHAUSEN, John O'LOUGHLIN, Bernice YEUNG, Yihong ZHANG
  • METHODS FOR MAINTAINING PEGYLATION OF POLYPEPTIDES
    Publication number: 20170049905
    Abstract: Described herein are methods for maintaining PEGylation and inhibiting dePEGylation of polypeptides, such as fibronectin-based scaffold proteins, during storage.
    Type: Application
    Filed: August 31, 2016
    Publication date: February 23, 2017
    Inventors: Bernice YEUNG, Jack Wang
  • Fibronectin based scaffold proteins having improved stability
    Patent number: 9562089
    Abstract: The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: February 7, 2017
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Ray Camphausen, John O'Loughlin, Bernice Yeung, Yihong Zhang
  • METHODS FOR MAINTAINING PEGYLATION OF POLYPEPTIDES
    Publication number: 20140187488
    Abstract: Described herein are methods for maintaining PEGylation and inhibiting dePEGylation of polypeptides, such as fibronectin-based scaffold proteins, during storage.
    Type: Application
    Filed: May 15, 2012
    Publication date: July 3, 2014
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Bernice Yeung, Jack Wang
  • FIBRONECTIN BASED SCAFFOLD PROTEINS HAVING IMPROVED STABILITY
    Publication number: 20130184212
    Abstract: The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
    Type: Application
    Filed: May 26, 2011
    Publication date: July 18, 2013
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Ray Camphausen, John O'Loughlin, Bernice Yeung, Yihong Zhang