Patents by Inventor Bethany Swencki-Underwood

Bethany Swencki-Underwood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CCL17
    Patent number: 9012602
    Abstract: Isolated polynucleotides encoding Macaca fascicularis CCL17 (CynoCCL17), polypeptides obtainable from expression of these polynucleotides, recombinant cells, and methods of use are disclosed.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: April 21, 2015
    Assignee: Janssen Biotech, Inc.
    Inventors: Michael Naso, Mary Ryan, Sandra Santulli-Marotto, Bethany Swencki-Underwood
  • ANTI-CD147 ANTIBODIES, METHODS AND USES
    Publication number: 20140079711
    Abstract: The present invention provides antibodies immunospecific for human CD147 capable of blocking bioactivity of CD147 associated with malignant disease such as the stimulation of MMPs from fibroblast cells by tumor cells, the release of VEGF, and the promotion of angiogenesis. The antibodies of the present invention of are useful in treating malignant disease and those diseases in which CD147 activity is plays a pathogenic role, such as diseases of the eye, lung, and cardiovascular system.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 20, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Mark Cunningham, Bethany Swencki-Underwood, Yi Tang, Li Yan
  • Anti-CD147 antibodies, methods and uses
    Patent number: 8618264
    Abstract: The present invention provides antibodies immunospecific for human CD147 capable of blocking bioactivity of CD147 associated with malignant disease such as the stimulation of MMPs from fibroblast cells by tumor cells, the release of VEGF, and the promotion of angiogenesis. The antibodies of the present invention of are useful in treating malignant disease and those diseases in which CD147 activity is plays a pathogenic role, such as diseases of the eye, lung, and cardiovascular system.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: December 31, 2013
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Mark Cunningham, Bethany Swencki-Underwood, Yi Tang, Li Yan
  • Baboon homolog of human CD147
    Patent number: 8338171
    Abstract: Polynucleotide sequences encoding a baboon homolog of human CD147 and polypeptides obtainable form the polynucleotides and uses are disclosed.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: December 25, 2012
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Bethany Swencki-Underwood, Michael Naso
  • Macaca fascicularis CCL17
    Publication number: 20120082622
    Abstract: Isolated polynucleotides encoding Macaca fascicularis CCL17 (CynoCCL17), polypeptides obtainable from expression of these polynucleotides, recombinant cells, and methods of use are disclosed.
    Type: Application
    Filed: September 26, 2011
    Publication date: April 5, 2012
    Inventors: Michael Naso, Mary Ryan, Sandra Santulli-Marotto, Bethany Swencki-Underwood
  • Polynucleotides encoding toll-like receptor 3
    Patent number: 8084232
    Abstract: Isolated polynucleotides encoding Papio cynocephalus Toll-Like Receptor 3 (Baboon TLR3), polypeptides obtainable from expression of these polynucleotides, recombinant cells, and methods of use are disclosed.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: December 27, 2011
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Jarrat Jordan, Jessica Schreiter, Bethany Swencki-Underwood
  • ANTI-CD147 ANTIBODIES, METHODS AND USES
    Publication number: 20110200627
    Abstract: The present invention provides antibodies immunospecific for human CD 147 capable of blocking bioactivity of CD 147 associated with malignant disease such as the stimulation of MMPs from fibroblast cells by tumor cells, the release of VEGF, and the promotion of angiogenesis. The antibodies of the present invention of are useful in treating malignant disease and those diseases in which CD 147 activity is plays a pathogenic role, such as diseases of the eye, lung, and cardiovascular system.
    Type: Application
    Filed: August 19, 2009
    Publication date: August 18, 2011
    Inventors: Mark Cunningham, Bethany Swencki-Underwood, Yi Tang, Li Yan
  • Cynomolgus gp80 receptor and uses thereof
    Patent number: 7931905
    Abstract: Isolated polynucleotides encoding cynomolgus monkey gp80, polypeptides obtainable from expression of these polynucleotides, compositions, recombinant cells, methods of making and using these polynucleotides, polypeptides, and compositions are useful in development of human therapeutics.
    Type: Grant
    Filed: May 21, 2009
    Date of Patent: April 26, 2011
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Michael Naso, Ronald Swanson, Bethany Swencki-Underwood
  • BABOON HOMOLOG OF HUMAN CD147
    Publication number: 20110052499
    Abstract: Polynucleotide sequences encoding a baboon homolog of human CD147 and polypeptides obtainable form the polynucleotides and uses are disclosed.
    Type: Application
    Filed: August 12, 2010
    Publication date: March 3, 2011
    Inventors: Bethany Swencki-Underwood, Michael Naso
  • Papio cynocephalus Toll-Like Receptor 3
    Publication number: 20100086487
    Abstract: Isolated polynucleotides encoding Papio cynocephalus Toll-Like Receptor 3 (Baboon TLR3), polypeptides obtainable from expression of these polynucleotides, recombinant cells, and methods of use are disclosed.
    Type: Application
    Filed: September 30, 2009
    Publication date: April 8, 2010
    Inventors: Jarrat Jordan, Jessica Schreiter, Bethany Swencki-Underwood
  • BMP-7 variant compositions, methods and uses
    Patent number: 7659250
    Abstract: Human Bone Morphogenic Protein 7 (hBMP-7) variant peptide chains, nucleic acids encoding these peptide chains, and methods of making and using the foregoing are disclosed.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: February 9, 2010
    Assignee: Centocor, Inc.
    Inventors: Bernard Amegadzie, Mark Cunningham, Haimanti Dorai, Jeffrey Luo, Juliane Mills, Bethany Swencki-Underwood
  • Cynomolgus gp80 Receptor and Uses
    Publication number: 20090291455
    Abstract: Isolated polynucleotides encoding cynomolgus monkey gp80, polypeptides obtainable from expression of these polynucleotides, compositions, recombinant cells, methods of making and using these polynucleotides, polypeptides, and compositions are useful in development of human therapeutics.
    Type: Application
    Filed: May 21, 2009
    Publication date: November 26, 2009
    Inventors: Michael Naso, Ronald Swanson, Bethany Swencki-Underwood
  • BMP-7 Variant Compositions, Methods and Uses
    Publication number: 20080032919
    Abstract: Human Bone Morphogenic Protein 7 (hBMP-7) variant peptide chains, nucleic acids encoding these peptide chains, and methods of making and using the foregoing are disclosed.
    Type: Application
    Filed: June 8, 2007
    Publication date: February 7, 2008
    Inventors: Bernard Amegadzie, Mark Cunningham, Haimanti Dorai, Jeffrey Luo, Juliane Mills, Bethany Swencki-Underwood