Patents by Inventor Betty Jin
Betty Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11007274Abstract: The present invention provides compounds for use in treating and/or preventing influenza. The compound comprises a first and second domain in which the first domain comprises at least one anchoring group which binds to the surface of influenza viruses and the second domain comprises at least one anionic group. The first and second domains are covalently linked. Also provided are pharmaceutically acceptable salts, solvates, prodrugs or stereoisomer of the compounds.Type: GrantFiled: May 18, 2018Date of Patent: May 18, 2021Assignee: Ausvir Therapeutics Pty LTDInventors: Betty Jin, Ee-Ling Seah, Paul Arthur Jones, Peter James Jenkins, Henry Kenneth Windle, Wen Yang Wu
-
Patent number: 10195226Abstract: A method of promoting recovery of cell viability of a damaged respiratory cell. The method includes a step of administering to the cell at least one pharmaceutically acceptable compound, which accelerates sialyglycoconjugate biosynthesis to restore sialylglycoconjugates on the surface of the respiratory cell. Also disclosed are a method and a pharmaceutical composition, both for treating a respiratory condition.Type: GrantFiled: May 8, 2015Date of Patent: February 5, 2019Assignee: Australian Biomedical Company Pty Ltd.Inventors: Betty Jin, Paul Arthur Jones, Ee Ling Seah, Wen Yang Wu, Peter James Jenkins
-
Publication number: 20180264128Abstract: The present invention provides compounds for use in treating and/or preventing influenza. The compound comprises a first and second domain in which the first domain comprises at least one anchoring group which binds to the surface of influenza viruses and the second domain comprises at least one anionic group. The first and second domains are covalently linked. Also provided are pharmaceutically acceptable salts, solvates, prodrugs or stereoisomer of the compounds.Type: ApplicationFiled: May 18, 2018Publication date: September 20, 2018Applicant: Australian Biomedical Co. Pty Ltd.Inventors: Betty Jin, Ee-Ling Seah, Paul Arthur Jones, Peter James Jenkins, Henry Kenneth Windle, Wen Yang Wu
-
Publication number: 20150238512Abstract: A method of promoting recovery of cell viability of a damaged respiratory cell. The method includes a step of administering to the cell at least one pharmaceutically acceptable compound, which accelerates sialyglycoconjugate biosynthesis to restore sialylglycoconjugates on the surface of the respiratory cell. Also disclosed are a method and a pharmaceutical composition, both for treating a respiratory condition.Type: ApplicationFiled: May 8, 2015Publication date: August 27, 2015Inventors: Betty Jin, Paul Arthur Jones, Ee Ling Seah, Wen Yang Wu, Peter James Jenkins
-
Patent number: 9040503Abstract: A method of promoting recovery of cell viability of a damaged respiratory cell. The method includes a step of administering to the cell at least one pharmaceutically acceptable compound, which accelerates sialyglycoconjugate biosynthesis to restore sialylglycoconjugates on the surface of the respiratory cell. Also disclosed are a method and a pharmaceutical composition, both for treating a respiratory condition.Type: GrantFiled: July 2, 2010Date of Patent: May 26, 2015Assignee: Australian Biomedical Company Pty Ltd.Inventors: Betty Jin, Paul Arthur Jones, Ee Ling Seah, Wen Yang Wu, Peter James Jenkins
-
Patent number: 8927565Abstract: Compositions including polymeric dialdehydes and compounds of where R1, R2, R7, R8, R9, and R10 may be the same or different and are selected from H, CH3, OH, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl; R3, R4, R5, R6 may be the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl, or R5 and R6 are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R3 and R4 together are ?O, or R4 and R6 are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R3 and R5 together form a double bond or are ?O, or R3 and R4, are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R5 and R6 together are ?O; R11 and R12 together form ?CH2, or R11 and R12 may be the same or different and are independently selected from the group consisting of H, CH3, CH2CH3 and CH2CH2CH3; and X is selected from the group consisting of Cl, Br, SO4, I and R13COO,Type: GrantFiled: August 26, 2004Date of Patent: January 6, 2015Assignee: Australian Biomedical Company Pty. Ltd.Inventors: Betty Jin, Wen-Yang Wu
-
Publication number: 20120142619Abstract: The present invention relates to a method and compounds of Formula (1) and/or (2) or their pharmaceutically acceptable inorganic or organic salt thereof, and their compositions for treating respiratory conditions including post viral/bacterial infections, acute/chronic bronchitis, COPD, cystic fibrosis, and inflammatory conditions. It has been found by the applicants that the compounds of Formula (1) and/or (2) or their pharmaceutically acceptable inorganic or organic salt thereof could speed up the recovery of the viability of damaged respiratory tract cells by restoring sialylglyco-conjugates on their surface.Type: ApplicationFiled: July 2, 2010Publication date: June 7, 2012Applicant: Australian Blomedical Company Pty Ltd,Inventors: Betty Jin, Paul Arthur Jones, Ee Ling Seah, Wen Yang Wu, Peter James Jenkins
-
Patent number: 7468388Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2-C9 alkyl C3-8 cycloalkyl, C1-C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.Type: GrantFiled: April 12, 2007Date of Patent: December 23, 2008Assignee: Biota Scientific Management Pty Ltd.Inventors: Betty Jin, Simon J. F. MacDonald, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu
-
Patent number: 7371755Abstract: This invention relates to a compound capable of binding to a picornavirus capsid comprising two or more capsid binding moieties.Type: GrantFiled: September 15, 2000Date of Patent: May 13, 2008Assignee: Biota Scientific Management Pty Ltd.Inventors: Guy Krippner, Phillip A. Reece, Keith G. Watson, Wen-Yang Wu, Betty Jin, Simon P. Tucker
-
Publication number: 20070293564Abstract: A method for the prevention of an orthomyxovirus or paramyxovirus infection comprising the step of administration to a subject in need thereof of an effective amount of a compound of formula (I)Type: ApplicationFiled: December 4, 2006Publication date: December 20, 2007Inventors: Michael Dowle, Betty Jin, Simon MacDonald, Andrew Mason, Darryl McConnell, Van Nguyen, Stephen Shanahan, Wen-Yang Wu
-
Publication number: 20070225358Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2-C9 alkyl C3-8 cycloalkyl, C1-C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.Type: ApplicationFiled: April 12, 2007Publication date: September 27, 2007Inventors: Betty JIN, Simon MacDonald, Darryl McConnell, Van Nguyen, Stephen Shanahan, Wen-Yang Wu
-
Patent number: 7223790Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2–C8 alkyl C3-8 cycloalkyl, C1–C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infectionType: GrantFiled: November 8, 2002Date of Patent: May 29, 2007Assignee: Biota Scientific Management Pty Ltd.Inventors: Betty Jin, Simon J. F. MacDonald, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu
-
Patent number: 7205333Abstract: The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. The invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or methods for the treatment and/or prophylaxis of a viral infection involving them.Type: GrantFiled: September 7, 2001Date of Patent: April 17, 2007Inventors: Wen-Yang Wu, Michael Dennis Dowle, Betty Jin, Simon John Fawcett Macdonald, Andrew McMurtrie Mason, Darryl McConnell, Keith Watson
-
Publication number: 20070027176Abstract: This invention is related to compositions including compounds of where R1, R2, R7, R8, R9, and R10 may be the same or different and are selected from H, CH3, OH, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl; R3, R4, R5, R6 may be the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl, or R5 and R6 are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R3 and R4 together are ?O, or R4 and R6 are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R3 and R5 together form a double bond or are ?O, or R3 and R4, are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R5 and R6 together are ?O; R11 and R12 together form ?CH2, or R11 and R12 may be the same or different and are independently selected from the group consisting of H, CH3, CH2CH3 and CH2CH2CH3; and X is selected from the group consisting of Cl, Br, SO4, I andType: ApplicationFiled: August 26, 2004Publication date: February 1, 2007Inventors: Betty Jin, Wen-Yang Wu
-
Patent number: 7157494Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, SO2NH, NHCO or NHCONH; m is either 0 or 1; n is an integer from 2 to 6; q is an integer from 0 to 3; and Y is hydrogen or an aromatic substituent, or a pharmaceutically acceptable derivative thereof; methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infectionType: GrantFiled: November 8, 2002Date of Patent: January 2, 2007Assignee: Biota Scientific Management Pty. Ltd.Inventors: Michael D. Dowle, Betty Jin, Simon J. F. Macdonald, Andrew McM Mason, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu
-
Patent number: 7078403Abstract: Disclosed herein are compounds of formula II: wherein Alk, Z, X1, X2, R1, —R10 and R11 are defined herein, and their salts and pharmaceutically acceptable derivatives thereof, as well as other compounds of the general formula Het-A-Alk-W-Ar-C(X2)?NO-X2 where Het, A, W and Ar are also defined herein. These compounds are useful in treating picornavirus infections in mammals. Novel intermediates of these compounds, as well as pharmaceutical compositions and methods of use, are also disclosed herein.Type: GrantFiled: June 16, 2000Date of Patent: July 18, 2006Assignee: Biota Scientific Management Pty Ltd.Inventors: Wen-Yang Wu, Keith Watson, Darryl McConnell, Betty Jin, Guy Krippner
-
Publication number: 20050085413Abstract: The invention relates to a compound of general formula (I): X-L-Y??(I) in which X and Y are pharmaceutically active moieties which may be the same or different; and L is a linker which is an optionally substituted saturated or unsaturated straight chain, branched and/or cyclic hydrocarbon radical having a backbone of at least 11 atoms, or a pharmaceutically acceptable derivative or salt thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a microbial infection.Type: ApplicationFiled: November 8, 2002Publication date: April 21, 2005Inventors: Betty Jin, John Lambert, Roland Nearn, Van Nguyen, Simon Tucker, Wen-Yang Wu
-
Publication number: 20050054719Abstract: The invention relates to compounds of general formula (1); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2-C8 alkyl C3-8 cycloalkyl, C1-C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.Type: ApplicationFiled: November 8, 2002Publication date: March 10, 2005Inventors: Betty Jin, Simon MacDonald, Darryl McConnell, Van Nguyen, Stephen Shanahan, Wen-Yang Wu
-
Publication number: 20050038108Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, SO2NH, NHCO or NHCONH; m is either 0 or 1; n is an integer from 2 to 6; q is an integer from 0 to 3; and Y is hydrogen or an aromatic substituent, or a pharmaceutically acceptable derivative thereof; methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.Type: ApplicationFiled: November 8, 2002Publication date: February 17, 2005Inventors: Michael Dowle, Betty Jin, Simon Macdonald, Andrew McM Mason, Darryl Mcconnell, Van Nguyen, Stepehn Shanahan, Wen-Yang Wu
-
Publication number: 20040058853Abstract: The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. The invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or methods for the treatment and/or prophylaxis of a viral infection involving them.Type: ApplicationFiled: October 14, 2003Publication date: March 25, 2004Inventors: Wen-Yang Wu, Michael Dennis Dowle, Betty Jin, Simon John Fawcett Macdonald, Andrew McMurtrie Mason, Darryl McConnell, Keith Watson