Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.

Abstract: Provided are body corrective cosmetic formulations and methods of use thereof.

Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.

Abstract: Compositions and methods of treating conditions of compromised skin hairier function are described.

Abstract: Provided are therapeutic formulations and methods of use thereof.

Abstract: Provided are body corrective cosmetic formulations and methods of use thereof.

Abstract: This invention relates to compositions and methods useful in treating dermatological disorders. In particular, the methods include applying a composition that includes a reactive reinforcing component; and a cross-linking component; in which the cross-linking component facilitates in situ cross-linking of the reactive reinforcing component, such that a film is formed on skin, thereby treating the dermatological disorder.

Abstract: The present invention provides durable, natural looking, non-invasive compositions that exhibit desired aesthetic qualities. Specifically, the compositions can be used for therapeutic treatments, including treatments of wounds and headaches. The invention pertains, at least in part, to therapeutic formulations for application to the skin that comprise a) a reactive reinforcing component; and b) a cross-linking component; in which the cross-linking component facilitates in situ formation of a film over the skin.

Abstract: Provided are body corrective cosmetic formulations and methods of use thereof.

Abstract: This invention provides assessment scale devices and methods for assessing the severity of wrinkles and facial swelling and puffiness. Wrinkle and facial swelling/puffiness assessment using the devices, methods, and assessment scales of the invention can be performed in a clinical setting for the purpose of simply characterizing a wrinkle or facial swelling/puffiness, or as part of a treatment plan or course that varies according to the severity of the wrinkle or facial swelling/puffiness. Thus, this invention also provides methods of reducing the appearance of wrinkles and/or facial puffiness, and kits comprising for evaluating and treating wrinkles and/or facial puffiness. Additionally, the present disclosure relates to a devices, methods, and assessment scales for managing expectations of the given treatment plan or course for human facial wrinkles and facial puffiness.

Abstract: Provided are body corrective cosmetic formulations and methods of use thereof.

Abstract: Provided are therapeutic formulations and methods of use thereof.

Abstract: Compositions and methods of for changing the color of skin or body are described.

Abstract: Provided are body corrective cosmetic formulations and methods of use thereof.

Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.

Abstract: Compositions and methods of treating conditions of compromised skin barrier function are described.

Abstract: Provided are body corrective cosmetic formulations and methods of use thereof.

Abstract: Provided are therapeutic formulations and methods of use thereof.