Abstract: A monolithic substrate of materials containing within it multiple opened channels of one dimensional macropore have a mesoporous inner surface and a method for making the same, wherein each of the opened channels is isolated from each other. The isolated channels of the one dimensional pore are aligned with and continuously extend through the entire substrate which contains various mesopores in three dimensions. The macropore has preferred pore sizes ranging from about 0.1 micrometers to about 20 micrometers, and the mesopore has a preferred pore size which is less than 500 angstrom.

Abstract: The present invention relates to LC packing materials in general, and silica-based HPLC packing materials in particular. Methods of forming and using the packing materials are also disclosed. The HPLC packing materials of the present invention feature high surface area and high porosity with good mechanical strength, due in part to the inclusion of a surfactant in the preparation of the LC packing materials. These desirable attributes are due, in part, to the narrow range of pore diameters that are generated in the preparation of the packing material.

Abstract: A protected fused-silica capillary liquid chromatography (liquid chromatography) column is shielded inside a single flexible tubing, which has the same length as the capillary and is integrated with the capillary in the packing process. The column has the advantages of a fused-silica capillary liquid chromatography column combined with the benefits of the shield tubing which makes the column more accurate, durable, and convenient to use, and less expensive to produce.