Patents by Inventor Bill Paspaliaris

Bill Paspaliaris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and apparatuses for isolating and preparing stem cells
    Patent number: 9752138
    Abstract: The present invention relates to a method of preparing a population of stem cells for autologous implantation to a subject. The cells are activated by irradiating the cells with one or more wavelengths of yellow and red and/or green light. In particular, the cells are irradiated with 575-595 nm (5-20 mW), and 630-635 nm or 660-670 nm (10-100 mW) and/or 510-540 nm (10-60 mW) of monochromatic light for 30-60 mins. Preferably the stem cells are adipose-derived stem cells. Also the invention relates to therapeutic applications of the activated stem cells.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: September 5, 2017
    Assignee: ADISTEM LTD.
    Inventors: Bill Paspaliaris, James Andrew Farrant Thornton
  • A METHOD OF PRODUCING EXOSOMES
    Publication number: 20160296560
    Abstract: The present application relates to methods of producing exosomes or extracts thereof for use in the treatment of diseases or disorders. In particular, the present invention relates to a method of producing exosomes or extracts thereof comprising the steps of: (a) exposing a population of isolated mammalian cells to light between 500 nm to 820 nm for sufficient time to enable said cells to produce and excrete said exosomes; and (b) separating said exosomes from other cellular components based on molecular weight, size, shape, composition or biological activity.
    Type: Application
    Filed: October 2, 2014
    Publication date: October 13, 2016
    Inventor: Bill PASPALIARIS
  • METHODS AND APPARATUSES FOR ISOLATING AND PREPARING STEM CELLS
    Publication number: 20140093482
    Abstract: The present invention relates to a method of preparing a population of stem cells for autologous implantation to a subject. The cells are activated by irradiating the cells with one or more wavelengths of yellow and red and/or green light. In particular, the cells are irradiated with 575-595 nm (5-20 mW), and 630-635 nm or 660-670 nm (10-100 mW) and/or 510-540 nm (10-60 mW) of monochromatic light for 30-60 mins. Preferably the stem cells are adipose-derived stem cells. Also the invention relates to therapeutic applications of the activated stem cells.
    Type: Application
    Filed: October 4, 2013
    Publication date: April 3, 2014
    Applicant: AdiStem, Ltd.
    Inventors: Bill Paspaliaris, James Andrew Farrant Thornton
  • [METHODS AND APPARATUSES FOR ISOLATING AND PREPARING STEM CELLS]
    Publication number: 20120101479
    Abstract: A method of preparing a population of stem cells for autologous implantation to a subject and apparatus used therein are provided. The cells are activated by irradiating the cells with one or more wavelengths of yellow and red and/or green light. In particular, the cells are irradiated with 575-595 nm (5-20 mW), and 630-635 nm or 660-670 nm (10-100 mW) and/or 510-540 nm (10-60 mW) of monochromatic light for 30-60 mins. Preferably the stem cells are adipose-derived stem cells. Therapeutic applications of the activated stem cells are also provided.
    Type: Application
    Filed: April 22, 2010
    Publication date: April 26, 2012
    Inventors: Bill Paspaliaris, James F. Thornton