Abstract: A homogenization process for coiled tubing is provided. After being preheated in a sectional manner and quenched and tempered, laser-welded low-carbon alloy steel coiled tubing is spray cooled, and then is tempered to obtain homogeneous silvery coiled tubing. Microstructural uniformity of the slivery coiled tubing after the treatment is greatly improved in a welding seam region, a heat sensing region, and a tube wall, situations in which an outer surface of the coiled tubing is burnt and oxidized in the homogenization process are reduced, and a service life of the coiled tubing is prolonged. Moreover, homogeneous coiled tubing with different yield strengths and tensile strengths can be obtained by changing a temperature of the tempering, so that production costs are reduced.

Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: [INSERT CHEMICAL STRUCTURE HERE] Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.

Abstract: Provided herein are methods for treating cancer and for selecting a cancer treatment based on the expression of Stag2/3 proteins and/or the presence of mutations in the genes encoding Stag2/3 proteins.

Abstract: A beta-glucosidase having improved enzymatic activity is disclosed. The amino acid sequence of the beta-glucosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of tyrosine at position 286 with phenylalanine, or a substitution of asparagine at position 639 with glutamate.

Abstract: The present invention relates to novel phosphorous (V) (P(V)) reagents, methods for preparing thereof, and methods for preparing organophosphorous (V) compounds by using the novel reagents.

Abstract: An eye gaze and hand data capturing system for use with a human performing a manual task (such as a surgical procedure) with a hand-held instrument (such as a surgical instrument), includes subsystems for tracking pupil position head position and orientation, hand position, and force applied by the hand to an instrument, all operatively connected to a computer that repeatedly determines an eye gaze vector, the hand position and orientation, and the force applied to the instrument and records such information as a record of spatially and temporally coherent data in a database.

Abstract: A method and system for monitoring an electrotherapy treatment applied to a subject in need of such therapy. An ultrasound transducer array is positioned adjacent a tissue of the subject to which the electrotherapy treatment is to be applied. The electrotherapy treatment is administered to the tissue as a plurality of ultra-short electric pulses which generate an electric field in the vicinity of the tissue. The ultrasound transducer array detects acoustic signals which are induced by the electric field. The detected acoustic signals are then used to construct tomographic images which represent the electric field generated by the electrotherapy treatment during real-time.

Abstract: A xylosidase having improved enzymatic activity is disclosed. The amino acid sequence of the xylosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of phenylalanine at position 35 with glutamate, and/or a substitution of glutamine at position 41 with histidine.

Abstract: A xylosidase having improved enzymatic activity is disclosed. The amino acid sequence of the xylosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of phenylalanine at position 35 with glutamate, and/or a substitution of glutamine at position 41 with histidine.

Abstract: A method for identifying metadata for cyber content sharing and governance (abbreviated as an MDCCSG method) and application method thereof. The MDCCSG method is proposed based on the requirements of big data sharing and governance under a big data and pan media environment, and is applicable for generating unified identifications on various categories of content resources; and the application method matched with the MDCCSG method can effectively support high-efficient sharing and governance of the big data, wherein the MDCCSG method comprises a unified description framework of metadata, a unified specification method of metadata, and a definition of the core MDCCSG identification element; and the MDCCSG method not only can describe rich semantics of contents in detail, but also has a built-in content trust authentication and security assurance ability.

Abstract: A glucose oxidase having improved thermostability is disclosed. The amino acid sequence of the glucose oxidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of glutamate at position 129 with proline, and/or a substitution of glutamine at position 243 with valine.

Abstract: The disclosure provides an apparatus and method for configuring DNS of a mobile device, and a storage medium. The apparatus includes: one or more processors; and a memory, wherein: the memory stores therein one or more computer readable program codes configured to be executed by the one or more processors to perform the operations of: functioning, by the mobile device, as a Wi-Fi relay to be connected with both a wireless access point and an electronic device; determining state information of communication between the wireless access point and the electronic device, forwarded by the relaying mobile device; determining whether communication is abnormal, according to the state information; and if so, then detecting a network service provider serving the mobile device; if the network service provider serving the mobile device is detected, then configuring a DNS list adapted to the network service provider; and configuring a DNS service of the mobile device according to the DNS list.

Abstract: Embodiments of this disclosure provide a relaying apparatus of a mobile device and an method thereof, the apparatus including: at least one processor; and a memory in which at least one instruction executable by the at least one processor is stored, wherein the at least one instruction is configured to be executed by the at least one processor: to connect the mobile device with a wireless access point; to obtain login information for logging into the mobile device; to enable a packet forwarding function to enable a data packet to be forwarded between different nodes of Wi-Fi in the mobile device; to send a relay instruction to a Wi-Fi module through a P2P node of Wi-Fi when the wireless access point is a router and the mobile device is connected with the router through a station node of Wi-Fi, so that the login information of the mobile device is broadcasted, and one or more electronic devices are connected through the P2P node; to send configuration information of packet forwarding to the Wi-Fi module to ena

Abstract: The present invention relates to a method and apparatus for evaluating hardware based on a cloud server, the method comprising: detecting information on hardware components of a computer terminal; determining the type of the computer terminal based on information on the hardware components of the computer terminal; and scoring the hardware components of the computer terminal based on information on the hardware components and the type of the computer terminal. In accordance with embodiments of the present invention, the hardware components are scored based on the type of the computer terminal, and the relevant database are timely updated to ensure the accuracy of the hardware scoring.

Abstract: Embodiments of the present application provide an apparatus and method for relaying by a mobile device, the apparatus including: a wireless access node connecting module configured to access to an external wireless access point through a station node of Wi-Fi inbuilt in the mobile device; a relay instruction sending module configured to send a relay instruction to a Wi-Fi module inbuilt in the mobile device through a P2P node of Wi-Fi inbuilt in the mobile device so that logon information of the mobile device is broadcasted, and one or more external electronic devices access to the mobile device through the P2P node; a packet forward enabling module configured to enable a packet forward function so that a data packet is forwarded between the different nodes of WiFi inbuilt in the mobile device; and a packet forward configuring module configured to send configuration information of packet forwarding to the Wi-Fi module so that a data packet is forwarded between the station node and the P2P node.

Abstract: An improved process for making a compound B of the structure wherein n, R1, R2, and R3 are as defined in the specification. Compound B can be used to make tubulysin analogs that are, in turn, useful as anti-cancer agents, particularly when deployed in an antibody-drug conjugate.

Abstract: The disclosure provides an apparatus and method for relaying by a mobile device and a storage medium, the apparatus including: one or more processors; and a memory, where: the memory stores therein one or more computer readable program codes configured to be executed by the one or more processors to perform operations of: connecting with a wireless access point through a station node of Wi-Fi; enabling a softAP node of Wi-Fi so that logon information of the mobile device is broadcasted, and one or more electronic devices are connected through the softAP node; enabling a packet forwarding function to enable a data packet to be forwarded between different nodes of Wi-Fi in the mobile device; and sending configuration information of packet forwarding to a Wi-Fi module so that a data packet is forwarded between the station node and the softAP node.