Patents by Inventor Bing-Sen Zhou

Bing-Sen Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ribonucleotide reductase inhibitors and methods of use
    Patent number: 8163783
    Abstract: Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme. These inhibitors may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: April 24, 2012
    Assignee: City of Hope
    Inventors: Yun Yen, David Horne, Yate-Ching Yuan, Bing-Sen Zhou, Angela L Perkins Harki, Leila Su
  • RIBONUCLEOTIDE REDUCTASE INHIBITORS AND METHODS OF USE
    Publication number: 20110245304
    Abstract: Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme. These inhibitors may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.
    Type: Application
    Filed: April 25, 2011
    Publication date: October 6, 2011
    Inventors: Yun YEN, David Horne, Yate-Ching Yuan, Bing-Sen Zhou, Angela L. Perkins Harki, Leila Su
  • Ribonucleotide reductase inhibitors and methods of use
    Patent number: 7956076
    Abstract: Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme. These inhibitors may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: June 7, 2011
    Assignee: City of Hope
    Inventors: Yun Yen, David Horne, Yate-Ching Yuan, Bing-Sen Zhou, Angela L Perkins Harki, Leila Su