Patents by Inventor Bishwa Prakash Rai

Bishwa Prakash Rai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE FORMS OF PALBOCICLIB
    Publication number: 20170240543
    Abstract: The present invention provides crystalline Form I, Form II, Form III, Form IV, Form V, Form V-A, Form VI, Form VII, and Form VIII of palbociclib, processes for their preparation, pharmaceutical compositions comprising these crystalline forms, and their use for the treatment of cyclin-dependent kinase associated diseases.
    Type: Application
    Filed: August 13, 2015
    Publication date: August 24, 2017
    Inventors: Sangeeta SANGWAN, Anu ARYA, Kallimulla MOHAMMAD, Bishwa Prakash RAI, Ram THAIMATTAM, Mohan PRASAD
  • A PROCESS FOR THE PREPARATION OF PALBOCICLIB
    Publication number: 20170217962
    Abstract: The present invention relates to a process for the preparation of palbociclib utilizing a silyl-protected crotonic acid derivative to produce a silyl-protected 2-chloro-4-(cyclopentylamino)-5-(1-methyl-2-carboxy-ethen-1-yl)pyrmidine followed by intramolecular cyclization of the pyrmidine intermediate to produce 2-chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one which is then converted to palbociclib.
    Type: Application
    Filed: July 21, 2015
    Publication date: August 3, 2017
    Inventors: Vipin TYAGI, Kallimulla MOHAMMAD, Bishwa Prakash RAI, Mohan PRASAD
  • PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF
    Publication number: 20140350240
    Abstract: The present invention relates to a process for the preparation of ceftaroline salts or hydrates thereof.
    Type: Application
    Filed: December 5, 2012
    Publication date: November 27, 2014
    Inventors: Kallimulla Mohammad, Bishwa Prakash Rai, Neera Tewari
  • PROCESS AND INTERMEDIATES FOR THE PREPARATION OF SUBSTITUTED 1,3-OXATHIOLANES, ESPECIALLY LAMIVUDINE
    Publication number: 20100311961
    Abstract: The present invention relates to process and intermediates for the preparation of substituted 1,3-oxathiolanes. The present invention specifically relates to a process for the preparation of lamivudine.
    Type: Application
    Filed: April 30, 2008
    Publication date: December 9, 2010
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Dinesh Shashidharan Nair, Bishwa Prakash Rai, Hashim Nizar Poovanathil Nagoor Meeran, Neera Tewari
  • Process for the preparation of imipenem
    Patent number: 7462712
    Abstract: The present invention relates to an improved process for the preparation of imipenem comprising reacting a bicyclo ketone precursor of the Formula II, wherein R is a protecting group, with a phosphorohalidate in the presence of a base and a catalytic amount of dialkylaminopyridine.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: December 9, 2008
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Neera Tewari, Bishwa Prakash Rai
  • Process for the preparation of crystalline imipenem
    Patent number: 7332600
    Abstract: The present invention relates to a cost effective and industrially advantageous process for the preparation of imipenem of high purity, which comprises dissolving crude imipenerm in warm water to which some base has been added to obtain a solution, subjecting the resultant solution to activated carbon treatment, and adding an organic solvent to precipitate imipienem monohydrate as a crystalline product.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: February 19, 2008
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Bishwa Prakash Rai, Neera Tewari, Yatendra Kumar
  • Process for the isolation of crystalline imipenem
    Patent number: 7241885
    Abstract: The present invention relates to a cost effective and industrially advantageous process for the preparation of imipenem of high purity comprising the steps of treating an aqueous solution containing imipenem with an organic solvent, wherein the imipenem is not lyophilized; and isolating the pure crystalline imipenem monohydrate from the reaction mixture thereof.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: July 10, 2007
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Neera Tewari, Ram Chander Aryan, Bishwa Prakash Rai
  • Process for the preparation of crystalline N-formimidoyl thienamycin monohydrate (imipenem monohydrate)
    Patent number: 7078534
    Abstract: The present invention relates to a cost effective and commercially viable process for the preparation of crystalline N-formimidoyl thienamycin monohydrate (Imipenem monohydrate) of Formula I.
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: July 18, 2006
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Neera Tewari, Ran Chander Aryan, Bishwa Prakash Rai, Seema Ahuja
  • Process for the isolation of crystalline imipenem
    Publication number: 20040242865
    Abstract: The present invention relates to a cost effective and industrially advantageous process for the preparation of imipenem of high purity.
    Type: Application
    Filed: June 17, 2004
    Publication date: December 2, 2004
    Inventors: Yatendra Kumar, Neera Tewari, Ram Chander Aryan, Bishwa Prakash Rai
  • Process for the preparation of imipenem
    Publication number: 20040220168
    Abstract: The present invention relates to an improved, cost effective and industrially advantageous process for the preparation of imipenem.
    Type: Application
    Filed: June 16, 2004
    Publication date: November 4, 2004
    Inventors: Yatendra Kumar, Neera Tewari, Bishwa Prakash Rai
  • Process for the preparation of crystalline n-formimidoyl thienamycin monohydrate (imipenem monohydrate)
    Publication number: 20040054167
    Abstract: The present invention relates to a cost effective and commercially viable process for the preparation of crystalline N-formimidoyl thienamycin monohydrate (Imipenem monohydrate) of Formula I.
    Type: Application
    Filed: September 18, 2003
    Publication date: March 18, 2004
    Inventors: Yatendra Kumar, Neera Tewari, Ran Chander Aryan, Bishwa Prakash Rai, Seema Ahuja
  • Method for manufacture of cephalosporin and intermediates thereof
    Patent number: 5945532
    Abstract: This invention relates to reactive derivatives of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetic acid and 1H-tetrazol-1-acetic acid of the following general formula I, ##STR1## wherein ##STR2## as well as to use thereof in the manufacture of cephalosporin antibiotics such as cefotaxime, ceftriaxone and cefazolin.
    Type: Grant
    Filed: September 16, 1998
    Date of Patent: August 31, 1999
    Assignee: Lupin Laboratories Limited
    Inventors: Debashish Datta, Vinod George, Bishwa Prakash Rai
  • Method for manufacture of cephalosporin and intermediates thereof
    Patent number: 5856502
    Abstract: This invention relates to reactive derivatives of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetic acid and 1H-tetrazol-1-acetic acid of the following general formula I, ##STR1## wherein ##STR2## as well as to use thereof in the manufacture of cephalosporin antibiotics such as cefotaxime, ceftriaxone and cefazolin.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: January 5, 1999
    Assignee: Lupin Laboratories Limited
    Inventors: Debashish Datta, Vinod George, Bishwa Prakash Rai
  • Process for manufacture of cephalosporin such as ceftazidime and intermediate thereof
    Patent number: 5831085
    Abstract: This invention relates to reactive derivative of 2-(2-amino-4-thiazolyl)-(Z)-2-?(1-tert butoxycarbonyl-l-methylethoxy) imino!acetic acid of the following formula I ##STR1## as well as to the use thereof in the manufacture of cephalosporin antibiotic such as ceftazidime of formula II.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: November 3, 1998
    Assignee: Lupin Laboratories Limited
    Inventors: Debashish Datta, Bishwa Prakash Rai, Kishor Mehre
  • Dimethyl formiminium chloride chlorosulphate derivatives useful as intermediates for producing cephalosporins
    Patent number: 5739346
    Abstract: This invention relates to reactive derivatives of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetic acid and 1H-tetrazol-1-acetic acid of the following general formula I, ##STR1## wherein R.sub.3 = ##STR2## as well as to use thereof in the manufacture of cephalosporin antibiotics such as cefotaxime, ceftriaxone and cefazolin.
    Type: Grant
    Filed: March 26, 1996
    Date of Patent: April 14, 1998
    Assignee: Lupin Laboratories Limited
    Inventors: Debashish Datta, Vinod George, Bishwa Prakash Rai