Patents by Inventor Bjarne Rønfeldt Nielsen

Bjarne Rønfeldt Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alpha-amylase variants
    Patent number: 8883970
    Abstract: The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency, specific activity, and solubility, in particular under production conditions.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: November 11, 2014
    Assignee: Novozymes A/S
    Inventors: Carsten Andersen, Torben Vedel Borchert, Bjarne Rønfeldt Nielsen
  • Stable formulations of peptides
    Patent number: 8748376
    Abstract: Stable pharmaceutical composition comprising insulinotropic peptide.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: June 10, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Svend Ludvigsen, Morten Schlein, Tine Elisabeth Gottschalk Bøving, Claude Bonde, Anne-Mette Lilleøre, Dorthe Kot Engelund, Bjarne Rønfeldt Nielsen
  • Glucoamylase variants
    Patent number: 8426183
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: April 23, 2013
    Assignee: Novozymes A/S
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Glucoamylase Variants
    Publication number: 20120088277
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Application
    Filed: December 19, 2011
    Publication date: April 12, 2012
    Applicant: NOVOZYMES A/S
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Glucoamylase variants
    Patent number: 8101392
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: January 24, 2012
    Assignee: Novozymes A/S
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • AMYLASE VARIANTS
    Publication number: 20110275136
    Abstract: The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency, specific activity, and solubility, in particular under production conditions.
    Type: Application
    Filed: July 20, 2011
    Publication date: November 10, 2011
    Applicant: Novozymes A/S
    Inventors: Carsten Andersen, Torben Vedel Borchert, Bjarne Rønfeldt Nielsen
  • ANTIBODY PURIFICATION PROCESS
    Publication number: 20110105725
    Abstract: The invention concerns a method for the industrial production of antibodies.
    Type: Application
    Filed: May 15, 2009
    Publication date: May 5, 2011
    Inventors: Bjarne Rønfeldt Nielsen, Hanne Christensen, Daniel E. Rasmussen, Thomas Budde Hansen, John Strikart Nielsen, Erik Halkjaer, Rikke Christina Nielsen, Christina Jespersgaard, Arne Staby
  • Glucoamylase Variants
    Publication number: 20110027836
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Application
    Filed: October 15, 2010
    Publication date: February 3, 2011
    Applicant: Novozymes A/S
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Glucoamylase variants
    Patent number: 7833772
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: November 16, 2010
    Assignee: Novozymes A/S
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Amylase variants
    Patent number: 7432099
    Abstract: The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency, specific activity, and solubility, in particular under production conditions.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: October 7, 2008
    Assignee: Novozymes A/S
    Inventors: Carsten Andersen, Torben Vedel Borchert, Bjarne Rønfeldt Nielsen
  • Glucoamylase variants
    Patent number: 7122365
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Grant
    Filed: January 2, 2002
    Date of Patent: October 17, 2006
    Assignee: Novozymes Als
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Alkaline amylase
    Patent number: 7078213
    Abstract: The present invention relates to amylases having improved washing performance in an alkaline detergent solution at low temperature. More specifically, the present invention provides novel ?-amylases from Bacillus sp. with improved performance in alkaline solutions, especially in alkaline detergent solutions at pH around 9–11.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: July 18, 2006
    Assignee: Novozymes A/S
    Inventors: Helle Outtrup, Bjarne Rønfeldt Nielsen, Lisbeth Hedegaard, Jens Toenne Andersen
  • Cyclomaltodextrin glucanotransferase variants
    Patent number: 6777215
    Abstract: The present invention relates to variants of cyclomaltodextrin glucanotransferase of increased product specificity.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: August 17, 2004
    Assignee: Novozymes A/S
    Inventors: Carsten Andersen, Bjarne Rønfeldt Nielsen, Lubbert Dijkhuizen, Bauke Dijkstra
  • Thermostable glucoamylase
    Patent number: 6620924
    Abstract: The invention relates to an isolated thermostable glucoamylase derived from Talaromyces emersonii suitable for starch conversion processes.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: September 16, 2003
    Assignee: Novozymes A/S
    Inventors: Bjarne Rønfeldt Nielsen, Ruby Ilum Nielsen, Jan Lehmbeck
  • Glucoamylase variants
    Publication number: 20030032163
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Application
    Filed: January 2, 2002
    Publication date: February 13, 2003
    Applicant: Novozymes A/S
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Glucoamylase variants
    Patent number: 6352851
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: March 5, 2002
    Assignee: Novozymes A/S
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Alkaline lipolytic enzyme
    Patent number: 6350604
    Abstract: Lipolytic enzymes with high activity at alkaline pH in the absence of Ca++ can be obtained from filamentous fungi of the genera Gliocladium, Verticillium and Trichophaea and that the lipolytic enzymes are effective for improving the effect of detergents. The lipolytic enzymes have a good washing performance, as expressed by the hydrolysis of oil on textile swatches. The amino acid sequences of the lipolytic enzymes are highly homologous.
    Type: Grant
    Filed: October 22, 1998
    Date of Patent: February 26, 2002
    Assignee: Novozymes A/S
    Inventors: Satoshi Hirayama, Rikako Taira, Kim Borch, Thomas Sandal, Torben Halkier, Karen Margrethe Oxenbøll, Bjarne Rønfeldt Nielsen
  • Method of producing saccharide preparations
    Patent number: 6303346
    Abstract: The present invention relates to a method for the production of saccharide preparations, i.e., syrups, by saccharifying a liquefied starch solution, which method comprises a saccharification step during which step one or more enzymatic saccharification stages takes place, and the subsequent steps of one or more high temperature membrane separation steps, and re-circulation of the saccharification enzyme, in which method the membrane separation steps are carried out as an integral part of the saccharification step. In another specific aspect, the invention provides a method of producing a saccharide preparation, which method comprises an enzymatic saccharification step, and the subsequent steps of one or more high temperature membrane separation steps and re-circulation of the saccharification enzyme.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: October 16, 2001
    Assignee: Novozymes A/S
    Inventors: Gin C. Liaw, Sven Pedersen, Hanne Vang Hendriksen, Allan Svendsen, Bjarne Rønfeldt Nielsen, Ruby Illum Nielsen
  • Cyclomaltodextrin glucanotransferase variants
    Patent number: 6271010
    Abstract: The present invention relates to variants of cyclomaltodextrin glucanotransferase of increased product specificity.
    Type: Grant
    Filed: September 22, 1998
    Date of Patent: August 7, 2001
    Assignee: Novzymes A/S
    Inventors: Carsten Andersen, Bjarne Rønfeldt Nielsen, Lubbert Dijkhuizen, Bauke Dijkstra
  • Thermostable glucoamylase
    Patent number: 6255084
    Abstract: The invention relates to an isolated thermostable glucoamylase derived from Talaromyces emersonii suitable for starch conversion processes.
    Type: Grant
    Filed: November 24, 1998
    Date of Patent: July 3, 2001
    Assignee: Novozymes A/S
    Inventors: Bjarne Rønfeldt Nielsen, Ruby Ilum Nielsen, Jan Lehmbeck