Patents by Inventor Blake T. Aftab

Blake T. Aftab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-CD46 ANTIBODIES AND METHODS OF USE
    Publication number: 20230383005
    Abstract: Disclosed herein are methods of treating a subject having a cancer characterized by a modification at biomarker 1q21, which comprises administering to the subject a therapeutically effective amount of an anti-CD46 antibody.
    Type: Application
    Filed: July 27, 2022
    Publication date: November 30, 2023
    Applicant: The Regents of the University of California
    Inventors: Bin Liu, Daniel W. Sherbenou, Blake T. Aftab, Yang Su, Christopher R. Behrens
  • ANTIGEN SPECIFIC CD19-TARGETED CAR-T CELLS
    Publication number: 20220348649
    Abstract: Disclosed are compositions and methods for targeted treatment of cancer, such as hematologic cancer. In particular, chimeric antigen receptor (CAR) T cells are disclosed that can be used with adoptive cell transfer to target and kill cancer cells with reduced antigen escape. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with hematologic cancer that involves adoptive transfer of the disclosed CAR T cells.
    Type: Application
    Filed: April 29, 2020
    Publication date: November 3, 2022
    Inventor: Blake T. Aftab
  • Anti-CD46 antibodies and methods of use
    Patent number: 11434301
    Abstract: Disclosed herein are methods of treating a subject having a cancer characterized by a modification at biomarker 1q21, which comprises administering to the subject a therapeutically effective amount of an anti-CD46 antibody.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: September 6, 2022
    Assignee: The Regents of the University of California
    Inventors: Bin Liu, Daniel W. Sherbenou, Blake T. Aftab, Yang Su, Christopher R. Behrens
  • COMPOSITIONS COMPRISING ANTI-CD38 ANTIBODIES AND CARFILZOMIB
    Publication number: 20220088194
    Abstract: Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and carfilzomib compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.
    Type: Application
    Filed: May 19, 2021
    Publication date: March 24, 2022
    Inventors: Blake TOMKINSON, Blake T. AFTAB, Byron C. HANN, Thomas G. MARTIN, III
  • METHODS FOR EXPANDING ANTIGEN-SPECIFIC CAR-T CELLS, COMPOSITIONS AND USES RELATED THERETO
    Publication number: 20210301255
    Abstract: Provided herein are methods for preparing and characterizing CAR-T cell cultures and preparations.
    Type: Application
    Filed: September 10, 2019
    Publication date: September 30, 2021
    Inventors: Blake T. Aftab, Christina Pham, Rhine Shen, Michelle Wu
  • COMPOSITIONS COMPRISING ANTI-CD38 ANTIBODIES AND LENALIDOMIDE
    Publication number: 20200046832
    Abstract: Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and lenalidomide compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.
    Type: Application
    Filed: June 5, 2019
    Publication date: February 13, 2020
    Inventors: Byron C. HANN, Blake TOMKINSON, Thomas G. MARTIN, III, Blake T. AFTAB
  • METHODS OF TREATING MULTIPLE SCLEROSIS USING AUTOLOGOUS T CELLS
    Publication number: 20190350981
    Abstract: Provided herein are compositions and methods related to the treatment of multiple sclerosis in a subject.
    Type: Application
    Filed: January 19, 2018
    Publication date: November 21, 2019
    Inventors: Rajiv Khanna, Corey Smith, Blake T. Aftab
  • COMPOSITIONS COMPRISING ANTI-CD38 ANTIBODIES AND CARFILZOMIB
    Publication number: 20190321471
    Abstract: Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and carfilzomib compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.
    Type: Application
    Filed: April 4, 2019
    Publication date: October 24, 2019
    Inventors: Blake TOMKINSON, Blake T. AFTAB, Byron C. HANN, Thomas G. MARTIN, III
  • ANTI-CD46 ANTIBODIES AND METHODS OF USE
    Publication number: 20190276553
    Abstract: Disclosed herein are methods of treating a subject having a cancer characterized by a modification at biomarker 1q21, which comprises administering to the subject a therapeutically effective amount of an anti-CD46 antibody.
    Type: Application
    Filed: November 10, 2017
    Publication date: September 12, 2019
    Inventors: Bin Liu, Daniel W. Sherbenou, Blake T. Aftab, Yang Su, Christopher R. Behrens
  • Compositions comprising anti-CD38 antibodies and lenalidomide
    Patent number: 10342869
    Abstract: Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and lenalidomide compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: July 9, 2019
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SANOFI
    Inventors: Byron C. Hann, Blake Tomkinson, Thomas G. Martin, III, Blake T. Aftab
  • COMPOSITIONS COMPRISING ANTI-CD38 ANTIBODIES AND CARFILZOMIB
    Publication number: 20170106085
    Abstract: Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and carfilzomib compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.
    Type: Application
    Filed: December 22, 2016
    Publication date: April 20, 2017
    Inventors: Blake TOMKINSON, Blake T. AFTAB, Byron C. HANN, Thomas G. MARTIN, III
  • COMPOSITIONS COMPRISING ANTI-CD38 ANTIBODIES AND CARFILZOMIB
    Publication number: 20160022813
    Abstract: Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and carfilzomib compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 28, 2016
    Inventors: Blake TOMKINSON, Blake T. AFTAB, Byron C. HANN, Thomas G. MARTIN, III
  • Compositions Comprising Anti-CD38 Antibodies and Lenalidomide
    Publication number: 20140161819
    Abstract: Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and lenalidomide compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.
    Type: Application
    Filed: December 6, 2013
    Publication date: June 12, 2014
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SANOFI
    Inventors: Byron C. Hann, Blake Tomkinson, Thomas G. Martin, III, Blake T. Aftab