Abstract: A wound therapy device includes a wound dressing and a humidifier configured to deliver humid air to a wound site to which the wound dressing is applied. The humidifier may be a remote structure that is fluidly connected to the wound dressing applied about a patient's skin at a wound site. Alternatively, the humidified may be integrated with the wound dressing to define an integral, portable therapy device that may be worn by the patient. The wound therapy device may be a standalone wound treatment device, or may be used in conjunction with other wound treatment devices, such as, e.g., negative pressure wound therapy devices.

Abstract: According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a wound dressing is provided comprising a scaffold coated with a biologically active composition comprising a lipoic acid derivative. In a further embodiment, a system is provided for treating a tissue site of a patient, the system comprising a reduced-pressure source to supply reduced pressure, a manifold to distribute reduced pressure to a tissue site and a scaffold coated with a biologically active composition comprising a lipoic acid derivative. Methods for producing such a system and scaffold are also disclosed.

Abstract: A system and apparatus for promoting perfusion at a tissue site containing a sprain by applying a vacuum to intact skin extending over or surrounding the tissue site. The system and apparatus comprise a manifold formed from a porous material and configured to be disposed proximate the intact skin for distributing vacuum to the intact skin, and a sleeve adapted to cover the manifold and form a chamber containing the manifold to seal the manifold within the chamber between the sleeve and the intact skin. The system and apparatus further comprise a fluid coupling member adapted to deliver vacuum to the manifold for distribution to the intact skin. A method for applying vacuum to the intact skin of a tissue site is also disclosed and described herein.

Abstract: A system and apparatus for promoting perfusion at a tissue site containing a sprain by applying a vacuum to intact skin extending over or surrounding the tissue site. The system and apparatus comprise a manifold formed from a porous material and configured to be disposed proximate the intact skin for distributing vacuum to the intact skin, and a sleeve adapted to cover the manifold and form a chamber containing the manifold to seal the manifold within the chamber between the sleeve and the intact skin. The system and apparatus further comprise a fluid coupling member adapted to deliver vacuum to the manifold for distribution to the intact skin. A method for applying vacuum to the intact skin of a tissue site is also disclosed and described herein.

Abstract: A wound therapy device includes a wound dressing and a humidifier configured to deliver humid air to a wound site to which the wound dressing is applied. The humidifier may be a remote structure that is fluidly connected to the wound dressing applied about a patient's skin at a wound site. Alternatively, the humidified may be integrated with the wound dressing to define an integral, portable therapy device that may be worn by the patient. The wound therapy device may be a standalone wound treatment device, or may be used in conjunction with other wound treatment devices, such as, e.g., negative pressure wound therapy devices.

Abstract: According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a wound dressing is provided comprising a scaffold coated with a biologically active composition comprising a lipoic acid derivative. In a further embodiment, a system is provided for treating a tissue site of a patient, the system comprising a reduced-pressure source to supply reduced pressure, a manifold to distribute reduced pressure to a tissue site and a scaffold coated with a biologically active composition comprising a lipoic acid derivative. Methods for producing such a system and scaffold are also disclosed.

Abstract: According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a wound dressing is provided comprising a scaffold coated with a biologically active composition comprising a lipoic acid derivative. In a further embodiment, a system is provided for treating a tissue site of a patient, the system comprising a reduced-pressure source to supply reduced pressure, a manifold to distribute reduced pressure to a tissue site and a scaffold coated with a biologically active composition comprising a lipoic acid derivative. Methods for producing such a system and scaffold are also disclosed.

Abstract: Skin graft harvesting systems and methods are disclosed that utilize sensors to automate the harvesting of skin grafts or assist a user in deciding when the skin graft is ready to be harvested. Such systems and methods can reduce the burden of visual observation and ensure greater reliability and consistency of the grafts. The invention is particularly useful with harvesters that rely upon suction and/or heating to raise a plurality of small or “micro” blisters simultaneously.

Abstract: In some non-limiting examples, a system for stimulating tissue growth at a tissue site may include an interactive body including a body mass and a tissue contact surface configured to contact the tissue site. A plurality of struts and a plurality of voids may be exposed at the tissue contact surface, and may define a tissue interface pattern at the tissue contact surface. The tissue interface pattern may be configured to engage the tissue site and to create tissue deformation in combination with the body mass. Also provided are other systems, apparatus, and methods suitable for stimulating tissue growth.

Abstract: The present application relates to devices and methods for harvesting skin graft sheets. The present invention provides a blister raising device comprising a blade assembly for cutting a blister sheet and an array of protrusions configured to prevent a portion of skin at the donor site from blistering.

Abstract: Devices and methods for skin graft harvesting are disclosed. In one aspect of the invention, substrates for transplanting skin grafts are disclosed that include a soft-tack, biocompatible composition having a surface adapted to contact at least one excised skin graft and engage the graft for removal from a donor site. In another aspect of the invention, at least a portion of the skin-contacting surface of the substrate (or dressing) is porous to facilitate fluid transport into (or out of) the graft site during harvesting and/or transplantation. The substrates can also incorporate an absorbent component to capture fluids. The substrate can be a mesh or fabric or web, e.g. woven, knitted, nonwoven or molded. The substrate can be a mesh of biocompatible fibers, for example, cellulosic, polyolefins, polyurethanes, polyesters or polyamide fibers. In one embodiment the mesh is formed of cellulose acetate fibers and coated with a silicone gel, to imparted the desire degree of tackiness.

Abstract: According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a topical composition is provided, which can be formulated as a homogenous mixture, such as a spray, mist, aerosol, lotion, cream, solution, oil, gel, ointment, paste, emulsion or suspension or applied on a carrier material, such as a bandage, gauze, foam, sponge, hydrogel, hydrocolloid, hydrofiber, occlusive dressing, adhesive composition or scaffold. Methods for producing such a topical composition and carrier material with the topical composition applied thereto are also disclosed.

Abstract: In some non-limiting examples, a system for stimulating tissue growth at a tissue site may include a porous foam and a moisture barrier. The porous foam may include an exterior-facing surface, a tissue contact surface, and a plurality of struts positioned at the tissue contact surface. The plurality of struts may be configured to contact the tissue site and to create tissue deformation at the tissue site without the application of a reduced pressure. The moisture barrier may be configured to cover the exterior-facing surface of the porous foam and to trap moisture at the tissue site. Also provided are other systems, apparatus, and methods suitable for stimulating tissue growth.

Abstract: A system for stimulating the healing of tissue comprises a porous pad positioned within a wound cavity, and an airtight dressing secured over the pad, so as to provide an airtight seal to the wound cavity. A proximal end of a conduit is connectable to the dressing. A distal end of the conduit is connectable to a negative pressure source, which may be an electric pump housed within a portable housing, or wall suction. A canister is positioned along the conduit to retain exudates suctioned from the wound site during the application of negative pressure. A controller for automated oscillation of pressure over time is provided to further enhance and stimulate the healing of an open wound. A power management motor control for varying pump drive frequency and managing a portable power supply is provided to increase battery life and improve patient mobility.

Abstract: A system and apparatus for promoting perfusion at a tissue site containing a sprain by applying a vacuum to intact skin extending over or surrounding the tissue site. The system and apparatus comprise a manifold formed from a porous material and configured to be disposed proximate the intact skin for distributing vacuum to the intact skin, and a sleeve adapted to cover the manifold and form a chamber containing the manifold to seal the manifold within the chamber between the sleeve and the intact skin. The system and apparatus further comprise a fluid coupling member adapted to deliver vacuum to the manifold for distribution to the intact skin. A method for applying vacuum to the intact skin of a tissue site is also disclosed and described herein.

Abstract: A system and apparatus for promoting perfusion at a tissue site containing a sprain by applying a vacuum to intact skin extending over or surrounding the tissue site. The system and apparatus comprise a manifold formed from a porous material and configured to be disposed proximate the intact skin for distributing vacuum to the intact skin, and a sleeve adapted to cover the manifold and form a chamber containing the manifold to seal the manifold within the chamber between the sleeve and the intact skin. The system and apparatus further comprise a fluid coupling member adapted to deliver vacuum to the manifold for distribution to the intact skin. A method for applying vacuum to the intact skin of a tissue site is also disclosed and described herein.

Abstract: Skin graft harvesting systems and methods are disclosed that utilize sensors to automate the harvesting of skin grafts or assist a user in deciding when the skin graft is ready to be harvested. Such systems and methods can reduce the burden of visual observation and ensure greater reliability and consistency of the grafts. The invention is particularly useful with harvesters that rely upon suction and/or heating to raise a plurality of small or “micro” blisters simultaneously.

Abstract: The present application relates to devices and methods for harvesting skin graft sheets. The present invention provides a blister raising device comprising a blade assembly for cutting a blister sheet and an array of protrusions configured to prevent a portion of skin at the donor site from blistering.

Abstract: According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a wound dressing is provided comprising a scaffold coated with a biologically active composition comprising a lipoic acid derivative. In a further embodiment, a system is provided for treating a tissue site of a patient, the system comprising a reduced-pressure source to supply reduced pressure, a manifold to distribute reduced pressure to a tissue site and a scaffold coated with a biologically active composition comprising a lipoic acid derivative. Methods for producing such a system and scaffold are also disclosed.

Abstract: The illustrative embodiments described herein are directed to a system and method for administering reduced pressure at a tissue site. The apparatus includes a reduced pressure source. The reduced pressure source generates a reduced pressure. The apparatus includes a tube having a plurality of lumens. The plurality of lumens includes at least one collection lumen. The reduced pressure source applies the reduced pressure to the tissue site through the plurality of lumens such that the at least one collection lumen receives fluid from the tissue site. The at least one collection lumen stores the fluid received from the tissue site.