Abstract: Approaches, techniques, and mechanisms are disclosed for the collection, distribution, and/or reporting of media content. According to an embodiment, media content items from one or more content providers are ingested into a content distribution system implemented by one or more server computer devices. These items of media content may comprise a variety of constituent elements, such as one or more video data units, one or more audio data units, descriptive metadata, subtitle units, thumbnails, or other information, which may be ingested all at once, or separately over time. Items may be processed using various workflows to refine content item components and/or generate new content items. Various publishing rules may be utilized to determine when the system is ready to publish a content item and distribute the item to client devices. Clients may request content items from various published listings, or search for content items by metadata and/or subtitles.

Abstract: The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR4 enzyme and are useful in the treatment of FGFR4-associated diseases such as cancer.

Abstract: Genetic male sterile plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production.

Abstract: The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR3 and/or FGFR4 enzyme and are useful in the treatment of FGFR-associated diseases.

Abstract: Genetic male sterile plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production.

Abstract: Approaches, techniques, and mechanisms are disclosed for the secure distribution of media content to devices having minimal or no Internet connectivity. Computing devices referred to herein as “local servers” are strategically deployed at various locations, such as stores and other public locations. Packages of media contents are stored on the local servers, and may be updated using various online and/or offline data transfer techniques. Portable devices may directly connect to the local servers via various types of proximity-based connections, such as by wireless local area networks, by wired connections over Universal Serial Bus cables, or by sharing of removable media such as Secure Digital cards. The local servers may copy their media contents to authorized devices when such connections are established. The contents on a device may be automatically be updated the next time the device connects to one of the local servers, so as to include newly selected and/or available content.

Abstract: The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR3 and/or FGFR4 enzyme and are useful in the treatment of FGFR-associated diseases.

Abstract: The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.

Abstract: A pipeline-based processor and method. The method includes partitioning a particular pipeline into one or more base pipeline stages and a plurality of enhanced pipeline stages, each enhanced pipeline stage configured to be either a shutdown enhanced pipeline stage or an activated enhanced pipeline stage. Each enhanced pipeline stage has an enhanced stage priority level. The method also includes configuring each enhanced pipeline stage to be activated or shut down based at least on the enhanced stage priority level. The method additionally includes partitioning a particular pipeline stage into at least one base module and a plurality of enhanced modules, each enhanced pipeline stage configured to be either a shutdown enhanced pipeline stage or an activated enhanced pipeline stage. Each enhanced module has a particular priority level. The method further includes configuring each enhanced module to be activated or shut down based at least on the particular priority level.

Abstract: The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.

Abstract: The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR4 enzyme and are useful in the treatment of FGFR4-associated diseases such as cancer.

Abstract: The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.

Abstract: Genetic male sterile plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production.

Abstract: Disclosed are compounds of Formula (I?), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.

Abstract: A method and system for servicing streaming media is disclosed. The method includes receiving the streaming media and determining an allocation of available processing and memory resources. In addition, the method includes performing a multi-stage service on the streaming media and caching an intermediate result from one of the stages of the multi-stage process. The intermediate result is selected according to the available processing and memory resources.

Abstract: A centralized authorization system authorizes content access requests for electronic content distributed over one or more networks in association with multiple third-party entities. Access to content is controlled by subscriptions. Subscriptions are requested by clients and granted if eligibility criteria are met. User accounts are assigned to different subscription states reflecting the states of their subscriptions. Subscription states may include, for example, an activated state, a deactivated state, a suspended state, a grace state, and/or a parking state. Different access rules are assigned to different states. A content authorization component authorizes content access requests based on applying these rules to the appropriate assigned states for the user accounts. The system includes a configuration interface by which third parties may configure specific access rules and other options that apply for their user accounts or subscriptions. Subscription retry and fallback logic may be provided.

Abstract: The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR4 enzyme and are useful in the treatment of FGFR4-associated diseases such as cancer.

Abstract: The present invention discloses a pipeline-based central processing unit, wherein the pipeline is partitioned into base pipeline stages and enhanced pipeline stages according to functions, the base pipeline stages being activated all the while, and the enhanced pipeline stages being activated or shutdown according to requirements for performance of a workload. The present invention further discloses a pipeline-based central processing unit, wherein the pipeline is partitioned into base pipeline stages and enhanced pipeline stages according to functions, each pipeline stage being partitioned into a base module and at least one enhanced module, the base module being activated all the while, and the enhanced module being activated or shutdown according to requirements for performance of a workload.

Abstract: A bit for removing damaged screws includes: a shaft portion and a head portion connected to the shaft portion. The head portion includes a tip section, a threaded conical section, and scraping portions extending continuously from the tip section to the threaded conical section. The scraping portions are able to perform continuous and non-stopping scraping operation toward the damaged screw. The scraping portions on the threaded conical section can scrape out a space big enough to allow passage of the threaded conical section, thus reducing resistance when the threaded conical section performs scraping and cutting operation. The threaded conical section can be guided to bite into and unscrew out the damaged screw, right after the scraping operation is performed by the tip section, so that the scraping and unscrewing operation can be performed more smoothly.