Patents by Inventor Bojan ISAILOVIC
Bojan ISAILOVIC has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240142478Abstract: A buffer management system includes at least one workstation configured to support a supply of concentrated buffer solution and an inline dilution skid having a manifold and at least one workstation to support delivery of diluted (surge) buffers from the inline dilution skid. The latter workstation also serves to supply ready-made (diluted) buffers to a bioprocessing unit. The manifold is in fluid communication with the supply of concentrated buffer solution and is adapted to be placed in fluid communication with a source of water for injection (WFI). The inline dilution skid is configured to variably mix the supply of concentrated buffer solution and the source of WFI to obtain a range of diluted buffer solutions. Processes for automatically identifying the arrangement of buffer solutions in a bioprocessing application use signals from various sensors to identify the fluid connections between components of the system.Type: ApplicationFiled: January 5, 2024Publication date: May 2, 2024Applicant: Cytiva US LLCInventors: Michael B. Seal, Darren G. Elton, Bojan Isailovic, Jeremy Rautenbach
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Patent number: 11899028Abstract: A buffer management system includes at least one workstation configured to support a supply of concentrated buffer solution and an inline dilution skid having a manifold and at least one workstation to support delivery of diluted (surge) buffers from the inline dilution skid. The latter workstation also serves to supply ready-made (diluted) buffers to a bioprocessing unit. The manifold is in fluid communication with the supply of concentrated buffer solution and is adapted to be placed in fluid communication with a source of water for injection (WFI). The inline dilution skid is configured to variably mix the supply of concentrated buffer solution and the source of WFI to obtain a range of diluted buffer solutions. Processes for automatically identifying the arrangement of buffer solutions in a bioprocessing application use signals from various sensors to identify the fluid connections between components of the system.Type: GrantFiled: December 18, 2020Date of Patent: February 13, 2024Assignee: Cytiva US LLCInventors: Michael B. Seal, Darren G. Elton, Bojan Isailovic, Jeremy Rautenbach
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Patent number: 11814200Abstract: A fluid distribution system includes single use distributor manifolds each having a distributor manifold inlet and a plurality of distributor manifold outlets in fluid communication with the distributor manifold inlet. A set of single use filler manifolds can be sequentially connected to a respective one of the outlets of a single use distributor manifold immediately upstream of the connection point of the set of single use filler manifolds. In embodiments, an upstream distributor manifold can be used to feed fluid to a set of intermediary distributor manifolds where the set of intermediary distributor manifolds corresponds to the number of outlets of the upstream distributor manifold.Type: GrantFiled: September 23, 2022Date of Patent: November 14, 2023Assignee: Cytiva US LLCInventors: Michael B. Seal, Bojan Isailovic, Robert Flisar, Jeremy Rautenbach
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Patent number: 11787680Abstract: A fluid distribution system includes single use distributor manifolds each having a distributor manifold inlet and a plurality of distributor manifold outlets in fluid communication with the distributor manifold inlet. A set of single use filler manifolds can be sequentially connected to a respective one of the outlets of a single use distributor manifold immediately upstream of the connection point of the set of single use filler manifolds. In embodiments, an upstream distributor manifold can be used to feed fluid to a set of intermediary distributor manifolds where the set of intermediary distributor manifolds corresponds to the number of outlets of the upstream distributor manifold.Type: GrantFiled: September 22, 2022Date of Patent: October 17, 2023Assignee: Cytiva US LLCInventors: Thomas J. Hartridge, Bojan Isailovic, Jens Bretschneider
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Publication number: 20230211994Abstract: A fluid distribution system includes single use distributor manifolds each having a distributor manifold inlet and a plurality of distributor manifold outlets in fluid communication with the distributor manifold inlet. A set of single use filler manifolds can be sequentially connected to a respective one of the outlets of a single use distributor manifold immediately upstream of the connection point of the set of single use filler manifolds. In embodiments, an upstream distributor manifold can be used to feed fluid to a set of intermediary distributor manifolds where the set of intermediary distributor manifolds corresponds to the number of outlets of the upstream distributor manifold.Type: ApplicationFiled: September 22, 2022Publication date: July 6, 2023Applicant: Pall CorporationInventors: Thomas J. Hartridge, Bojan Isailovic, Jens Bretschneider
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Publication number: 20230211905Abstract: A fluid distribution system includes single use distributor manifolds each having a distributor manifold inlet and a plurality of distributor manifold outlets in fluid communication with the distributor manifold inlet. A set of single use filler manifolds can be sequentially connected to a respective one of the outlets of a single use distributor manifold immediately upstream of the connection point of the set of single use filler manifolds. In embodiments, an upstream distributor manifold can be used to feed fluid to a set of intermediary distributor manifolds where the set of intermediary distributor manifolds corresponds to the number of outlets of the upstream distributor manifold.Type: ApplicationFiled: September 23, 2022Publication date: July 6, 2023Applicant: Pall CorporationInventors: Michael B. Seal, Bojan Isailovic, Robert Flisar, Jeremy Rautenbach
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Publication number: 20210199679Abstract: A buffer management system includes at least one workstation configured to support a supply of concentrated buffer solution and an inline dilution skid having a manifold and at least one workstation to support delivery of diluted (surge) buffers from the inline dilution skid. The latter workstation also serves to supply ready-made (diluted) buffers to a bioprocessing unit. The manifold is in fluid communication with the supply of concentrated buffer solution and is adapted to be placed in fluid communication with a source of water for injection (WFI). The inline dilution skid is configured to variably mix the supply of concentrated buffer solution and the source of WFI to obtain a range of diluted buffer solutions. Processes for automatically identifying the arrangement of buffer solutions in a bioprocessing application use signals from various sensors to identify the fluid connections between components of the system.Type: ApplicationFiled: December 18, 2020Publication date: July 1, 2021Applicant: Pall CorporationInventors: Michael B. Seal, Darren G. Elton, Bojan Isailovic, Jeremy Rautenbach
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Publication number: 20210197189Abstract: A buffer management system includes a supply of concentrated buffer solution, an inline dilution skid having a manifold in fluid communication with the supply of concentrated buffer solution and a control unit configured to operate the dilution skid to selectively dilute the supply of concentrated buffer solution in the manifold with a source of water for injection (WFI), and a biocontainer assembly. The biocontainer assembly includes a biocontainer bag defining a storage volume and a fill level sensor configured to generate a fill level signal indicative of the amount of material within the storage volume of the biocontainer bag. The biocontainer bag is in fluid communication with the manifold of the dilution skid for storing diluted buffer solution therein. The fill level sensor communicates the fill level signal to the control unit of the dilution skis, which uses it to manage the operation of the dilution skid.Type: ApplicationFiled: December 18, 2020Publication date: July 1, 2021Applicant: Pall CorporationInventors: Bojan Isailovic, Michael B. Seal, Matthew J. Loveless, Robert Flisar, Damir F. Söhngen
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Patent number: 9880067Abstract: A mechanically driven agitator for use in bioprocessing, including a seal housing providing an integral seal around the agitator shaft is provided. Additionally, a fluid mixing assembly comprising a container and the agitator, as well as a support assembly for supporting the fluid mixing assembly, the support assembly further comprising a mounting assembly for lockably engaging the seal housing, are also provided.Type: GrantFiled: December 3, 2013Date of Patent: January 30, 2018Assignee: Pall CorporationInventor: Bojan Isailovic
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Publication number: 20150151261Abstract: A mechanically driven agitator for use in bioprocessing, including a seal housing providing an integral seal around the agitator shaft is provided. Additionally, a fluid mixing assembly comprising a container and the agitator, as well as a support assembly for supporting the fluid mixing assembly, the support assembly further comprising a mounting assembly for lockably engaging the seal housing, are also provided.Type: ApplicationFiled: December 3, 2013Publication date: June 4, 2015Inventor: Bojan ISAILOVIC