Abstract: An improved process for preparing iodophor preparations which comprises adding an ion selected from the group consisting of iodate, bromate, chlorite, chromate, hypochlorite, permanganate and persulfate ions and hydrogen peroxide to the iodine carrier selected from the group consisting of povidone, cationic, anionic and nonionic detergent compounds and an iodide salt, to result in a substantially pure iodophor compound which is virtually free of autodegraded iodide ion contamination and unreacted elemental iodine, said iodophor compounds exhibiting an enhanced stability. The process is also applicable to eliminate the presence of elemental iodine contaminants, iodide contamination and loss of titratable iodine during the process preparing pharmaceutical dosage forms containing iodophor active ingredients to enhance the stability and potency of the respective product.

Abstract: Adamantane derivatives such as .beta.-(1-adamantyl)-.alpha.,.alpha.-dimethylethylamine hydrochloride, .beta.-(1-adamantyl)-.alpha.-methylethylamine hydrochloride, d-.beta.-(1-adamantyl)-.alpha.-methylethylamine hydrochloride, and 1-.beta.-(1-adamantyl)-.alpha.-methylethylamine hydrochloride have anorectic activity.The hydrazine derivatives of the above compounds are antihypertensive agents, and monoamine oxidase inhibitors.

Abstract: 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones, acid addition salts thereof, and intermediate compounds having analgesic properties. A representative quinazolinone compound is 1-[2-(1-phenyl-4-piperazinyl)-ethyl]-2-phenyl-1,2,3,4-tetrahydro-4-quinazo linone. A representative analgesic intermediate is 2-[2-(4-[1-phenyl]piperazinyl) ethylamino] benzamide.

Abstract: 1-heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones, acid addition salts thereof, and intermediate compounds having analgesic properties. A representative quinazolinone compound is 1-[2-(1-phenyl-4-piperazinyl)-ethyl]-2-phenyl-1,2,3,4-tetrahydro-4-quinazo linone. A representative analgesic intermediate is 2-[2-(4-[1-phenyl]piperazinyl)ethylamino]benzamide.

Abstract: Analgesics, local anesthetics, and antiarrhythmics which are 1-(amino-alkyl)-2-aryl-cyclohexane alcohols and esters having the structure ##SPC1##WhereinR.sup.1 is hydrogen or alkanoyl; R.sup.2 and R.sup.3 individually are hydrogen, lower alkyl, or lower alkenyl, or R.sup.2 and R.sup.3 together with the nitrogen to which they are attached form a morpholine radical, a piperazine radical or a carbocyclic ring; R.sup.4 is hydrogen or lower alkyl; R.sup.5 and R.sup.6 individually are hydrogen, lower alkyl, hydroxyl or lower alkoxy; and the pharmaceutically acceptable acid addition and quaternary salts thereof, as well as stereoisomers and optical isomers thereof. This invention relates also to processes for making and using the foregoing compounds.