Abstract: The present invention provides a pharmaceutical composition for preventing or treating colitis comprising tegoprazan, which is a benzimidazole derivative compound, as an effective ingredient.

Abstract: The present disclosure relates to a pharmaceutical composition containing a benzimidazole derivative compound. Specifically, the present disclosure relates to a formulation capable of maintaining a sustained blood concentration of the benzimidazole derivative compound.

Abstract: A separator for an electrochemical device includes a first porous coating layer on a first surface of a porous polymer substrate. The first porous coating layer includes inorganic particles and a first binder polymer, and the first porous coating layer has an interstitial volume pore structure. The separator also includes a second porous coating layer on a second surface of the porous polymer substrate. The second porous coating layer includes second inorganic particles and a second binder polymer. The second porous coating layer having a node-filament pore structure. The separator also includes an electrode adhesion layer on a surface of the first porous coating layer opposite to the porous separator substrate. The electrode adhesion layer includes a third binder polymer. The separator for an electrochemical device has high heat resistance and improved adhesive property with electrode. An electrochemical device having the separator is also provided.

Abstract: The present invention relates to a pharmaceutical composition for preventing peptic ulcer and/or recurrence thereof containing a benzimidazole derivative. The pharmaceutical composition of the present invention may effectively prevent peptic ulcer and/or recurrence thereof, which may be caused by administration of a non-steroidal anti-inflammatory drug, for a long period of time without side effects.

Abstract: The present disclosure relates to a pharmaceutical composition that delayed-releases tegoprazan and releases clopidogrel immediately. The pharmaceutical composition may exhibit significantly excellent effects on the prevention and treatment of gastrointestinal disorders caused by administration of clopidogrel and thrombosis-related diseases.

Abstract: Disclosed are a crosslinked separator for a lithium secondary battery which comprises a crosslinked polyolefin porous substrate including a plurality of fibrils and pores formed by the fibrils entangled with one another, wherein polyolefin chains forming the fibrils are crosslinked directly with one another; and shows a change in tensile strength of 20% or less in the machine direction, as compared to a non-crosslinked separator including a polyolefin porous substrate before crosslinking, and a method for manufacturing the same. The crosslinked separator for a lithium secondary battery has excellent thermal safety, while not adversely affecting the other physical properties.

Abstract: A composite separator for an electrochemical device, including: a porous polymer substrate having a plurality of pores; and a porous coating layer formed on at least one surface of the porous polymer substrate. The porous coating layer includes a plurality of particles and a binder positioned on at least a part of the surface of the particles to connect and fix the particles with one another. The particles include at least one of inorganic particles or organic particles, and the composite separator has a melt-down temperature of 170° C. or higher. An electrochemical device including the composite separator is also disclosed.

Abstract: A separator for a lithium secondary battery is provided. The separator includes a porous polymer substrate and a porous coating layer positioned on at least one surface of the porous polymer substrate. The porous coating layer includes inorganic particles and a binder polymer. The binder polymer includes a PVdF-based binder polymer, and the PVdF-based binder polymer has a first peak at a 2? of 18.2±0.2° and a second peak at a 2? of 19.8±0.2°, as analyzed by X-ray diffractometry (XRD), and a ratio of an area of the second peak to an area of the first peak (the area of the second peak/the area of the first peak) is equal to or more than 1.25 and less than 2.75. The separator for the lithium secondary battery includes fine and uniform pores formed on the surface thereof to provide an increased adhesive surface area to an electrode, resulting in improvement of adhesion to the electrode.

Abstract: A lithium secondary battery separator with excellent adhesive strength and air permeability is disclosed. The lithium secondary battery separator includes a porous polymer substrate; and a porous coating layer containing inorganic particles and a binder. When the binder is present as a binder specimen with a thickness of 0.4 mm after pressurization at 190° C., the binder specimen comprises a first binder having a tan ? peak at 15° C. to 27.6° C. and a second binder having a tan ? peak at 8° C. to 20.2° C., as measured by dynamic mechanical analysis (DMA).

Abstract: The present invention relates to a pharmaceutical composition for preventing the recurrence of gastroesophageal reflux disease, comprising a benzimidazole derivative. The pharmaceutical composition of the present invention may effectively prevent the recurrence of gastroesophageal reflux disease without any side effects for a long period of time.

Abstract: The present invention relates to a composition for eradicating Helicobacter pylori and a use thereof. The composition of the present invention maintains an intragastric pH at a certain level or more for a certain period of time or longer, thereby maximizing an action of amoxicillin and clarithromycin to show an excellent effect on eradicating Helicobacter pylori.

Abstract: The present invention relates to a use of benzimidazole derivative compounds for improvement and treatment of nocturnal acid breakthrough (NAB). The benzimidazole derivative compounds can more effectively prevent and treat gastric acid-related diseases by effectively improving and treating nocturnal nocturnal acid breakthrough symptoms.

Abstract: The present invention relates to a use of benzimidazole derivative compounds for improvement and treatment of nocturnal acid breakthrough (NAB). The benzimidazole derivative compounds can more effectively prevent and treat gastric acid-related diseases by effectively improving and treating nocturnal nocturnal acid breakthrough symptoms.

Abstract: The present invention relates to a use of benzimidazole derivative compounds for improvement and treatment of nocturnal acid breakthrough (NAB). The benzimidazole derivative compounds can mere effectively prevent and treat gastric acid-related diseases by effectively improving and treating nocturnal nocturnal acid breakthrough symptoms.

Abstract: The present invention relates to a use of benzimidazole derivative compounds for improvement and treatment of nocturnal acid breakthrough (NAB). The benzimidazole derivative compounds can mere effectively prevent and treat gastric acid-related diseases by effectively improving and treating nocturnal nocturnal acid breakthrough symptoms.

Abstract: The present invention discloses a method for preparing a microporous polyolefin film comprising: a step of injecting a composition comprising polyolefin 30 to 60 wt % and a diluent mixture comprising a diluent, which can make liquid-liquid phase separation with the polyolefin thermodynamically 40 to 70 wt %, into an extruding machine, and melting and kneading thereof to prepare a single phase melt; and a step of extruding the melt while conducting liquid-liquid phase separation by passing through a section having the temperature below the liquid-liquid phase separation temperature and forming thereof in the form of a sheet, and a microporous polyolefin film prepared according to the method.

Abstract: The present invention discloses a method for preparing a microporous polyolefin film comprising: a step of injecting a composition comprising polyolefin 30 to 60 wt % and a diluent, which can make liquid-liquid phase separation with the polyolefin thermodynamically 40 to 70 wt %, into an extruding machine, and melting and kneading thereof to prepare a single phase melt; and a step of extruding the melt while conducting liquid-liquid phase separation by passing through a section having the temperature below the liquid-liquid phase separation temperature and forming thereof in the form of a sheet, and a microporous polyolefin film prepared according to the method.

Abstract: The present invention proposes a wavelength division multiplexing-passive optical network (WDM-PON) system which transmits downstream data to an optical network unit (ONU) as an optical line termination (OLT) receives seed light from a spectrum-sliced external light source module. One characteristic of the proposed WDM-PON system is that optical transmitters of the OLT and ONU are operated regardless of optical wavelength. Another characteristic of the proposed WDM-PON system is that a conventional TDMA-PON (E-PON or G-PON) ONU can be accommodated without a change.

Abstract: The present invention discloses a method for preparing a microporous polyolefin film comprising: a step of injecting a composition comprising polyolefin 30 to 60 wt % and a diluent, which can make liquid-liquid phase separation with the polyolefin thermodynamically 40 to 70 wt %, into an extruding machine, and melting and kneading thereof to prepare a single phase melt; and a step of extruding the melt while conducting liquid-liquid phase separation by passing through a section having the temperature below the liquid-liquid phase separation temperature and forming thereof in the form of a sheet, and a microporous polyolefin film prepared according to the method.

Abstract: The present invention discloses a method for preparing a microporous polyolefin film comprising: a step of injecting a composition comprising polyolefin 30 to 60 wt % and a diluent mixture comprising a diluent, which can make liquid-liquid phase separation with the polyolefin thermodynamically 40 to 70 wt %, into an extruding machine, and melting and kneading thereof to prepare a single phase melt; and a step of extruding the melt while conducting liquid-liquid phase separation by passing through a section having the temperature below the liquid-liquid phase separation temperature and forming thereof in the form of a sheet, and a microporous polyolefin film prepared according to the method.