Patents by Inventor Boren Lin

Boren Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biosensor device to target analytes in situ, in vivo, and/or in real time, and methods of making and using the same
    Patent number: 10849540
    Abstract: A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The transducer component includes the electrode and microprocessor configured to screen noise and to pick up impedance change at a very low frequency range.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: December 1, 2020
    Assignee: The University of Toledo
    Inventors: Anand K. Agarwal, Vijay K. Goel, Dong-Shik Kim, Do Young Yoon, Boren Lin, Hamid Feyzizarnagh
  • A BIOSENSOR DEVICE TO DETECT TARGET ANALYTES IN SITU, IN VIVO, AND/OR IN REAL TIME, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20180271423
    Abstract: A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The SAM layer may include an anti-fouling agent. The transducer component includes an electrode (or set of electrodes that includes a working electrode) and microprocessor configured to screen noise and to pick up a detectable signal, such as impedance change at a very low frequency range.
    Type: Application
    Filed: October 6, 2016
    Publication date: September 27, 2018
    Applicant: The University of Toledo
    Inventors: Anand K. Agarwal, Vijay K. Goel, Dong-Shik Kim, Boren Lin
  • Injectable Biodegradable Bone Matrix for Multiple Myeloma Lesion Augmentation and Osteoporosis
    Publication number: 20160030631
    Abstract: Bone filler compositions, methods of making and using the same, and methods of treating osteoporosis and cancer-induced bone defects, are described.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 4, 2016
    Applicant: THE UNIVERSITY OF TOLEDO
    Inventors: Anand K. Agarwal, Vijay K. Goel, Dong-Shik Kim, Sarit B. Bhaduri, Boren Lin
  • A Biosensor Device to Target Analytes in Situ, in Vivo, and/or in Real Time, and Methods of Making and Using the Same
    Publication number: 20160022185
    Abstract: A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The transducer component includes the electrode and microprocessor configured to screen noise and to pick up impedance change at a very low frequency range.
    Type: Application
    Filed: March 11, 2014
    Publication date: January 28, 2016
    Applicant: THE UNIVERSITY OF TOLEDO
    Inventors: Anand K. Agarwal, Vijay K. Goel, Dong-Shik Kim, Do-Young Yoon, Boren Lin, Hamid Feyzizarnagh