Patents by Inventor Boris C. Bastian

Boris C. Bastian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-kit oncogene mutations in melanoma
    Patent number: 10260101
    Abstract: The present invention provides methods of detecting c-KIT-dependent-melanoma for diagnostic and prognostic purposes. The invention further provides methods of treating such melanoma by inhibiting c-KIT.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: April 16, 2019
    Assignee: The Regents of the University of California
    Inventors: Boris C. Bastian, John A. Curtin
  • FUSION POLYNUCLEOTIDES AND FUSION POLYPEPTIDES ASSOCIATED WITH CANCER AND PARTICULARLY MELANOMA AND THEIR USES AS THERAPEUTIC AND DIAGNOSTIC TARGETS
    Publication number: 20160010068
    Abstract: Novel fusion molecules and uses are disclosed.
    Type: Application
    Filed: February 24, 2014
    Publication date: January 14, 2016
    Inventors: Boris C. BASTIAN, Maureen CRONIN, Jie HE, Doron LIPSON, Philip James STEPHENS, Thomas WIESER, Roman YALENSKY
  • GNA11 mutations in melanoma
    Patent number: 8927215
    Abstract: The present invention provides methods of detecting mutations in a GNA11 gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated GNA11 gene.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: January 6, 2015
    Assignees: The Regents of the University of California, The University of British Columbia, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Boris C. Bastian, Catherine D. Van Raamsdonk, Gregory S. Barsh
  • C-Kit Oncogene Mutations in Melanoma
    Publication number: 20140045182
    Abstract: The present invention provides methods of detecting c-KIT-dependent-melanoma for diagnostic and prognostic purposes. The invention further provides methods of treating such melanoma by inhibiting c-KIT.
    Type: Application
    Filed: October 16, 2013
    Publication date: February 13, 2014
    Applicant: The Regents of the University of California
    Inventors: Boris C. Bastian, John A. Curtin
  • mutations in melanoma
    Patent number: 8501404
    Abstract: The present invention provides methods of detecting mutations in a Gnaq gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated Gnaq gene.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: August 6, 2013
    Assignees: The Regents of the University of California, The Board of Trustees of the Leland Stanford Junior University, The University of British Columbia
    Inventors: Boris C. Bastian, Catherine D. Van Raamsdonk, Gregory S. Barsh
  • GNA11 AND GNAQ EXON 4 MUTATIONS IN MELANOMA
    Publication number: 20130102653
    Abstract: The present invention provides methods of detecting activating mutations in exon 4 of a GNAQ or a GNA11 gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated GNAQ or GNA11.
    Type: Application
    Filed: April 15, 2011
    Publication date: April 25, 2013
    Applicants: The Univeristy of British Columbia, The Regents of the University of California
    Inventors: Klaus G. Griewank, Boris C. Bastian, Catherine D. Van Raamsdonk
  • GNA11 MUTATIONS IN MELANOMA
    Publication number: 20130058938
    Abstract: The present invention provides methods of detecting mutations in a GNA11 gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated GNA11 gene.
    Type: Application
    Filed: October 29, 2010
    Publication date: March 7, 2013
    Applicants: The Regents of the University of California, The Board of Trustees of the Leland Stanford Junior University, The University of British Columbia
    Inventors: Boris C. Bastian, Catherine D. Van Raamsdonk, Gregory S. Barsh
  • GNAQ MUTATIONS IN MELANOMA
    Publication number: 20110070221
    Abstract: The present invention provides methods of detecting mutations in a Gnaq gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated Gnaq gene.
    Type: Application
    Filed: February 8, 2008
    Publication date: March 24, 2011
    Inventors: Boris C. Bastian, Catherine D. Van Raamsdonk, Gregory S. Barsh
  • C-Kit Oncogene Mutations in Melanoma
    Publication number: 20080274469
    Abstract: The present invention provides methods of detecting c-KIT-dependent-melanoma for diagnostic and prognostic purposes. The invention further provides methods of treating such melanoma by inhibiting c-KIT.
    Type: Application
    Filed: October 23, 2006
    Publication date: November 6, 2008
    Applicant: The Regents of The University of California
    Inventors: Boris C. Bastian, John A. Curtin
  • Genetic changes in atypical nodular proliferations in congenital melanocytic nevi
    Patent number: 6783944
    Abstract: The invention provides methods of distinguishing benign growths arising from congenital melanocytic nevi from malignant melanoma. The methods comprise detecting a change in chromosome number that is specifically associated with benign growths. These changes include a gain of chromosome 10, a gain of chromosome 11, and a loss of chromosome 7.
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: August 31, 2004
    Assignee: The Regents of the University of California
    Inventor: Boris C. Bastian
  • Genetic changes in atypical nodular proliferations in congenital melanocytic nevi
    Publication number: 20030143543
    Abstract: The invention provides methods of distinguishing benign growths arising from congenital melanocytic nevi from malignant melanoma. The methods comprise detecting a change in chromosome number that is specifically associated with benign growths. These changes include a gain of chromosome 10, a gain of chromosome 11, and a loss of chromosome 7.
    Type: Application
    Filed: January 4, 2002
    Publication date: July 31, 2003
    Applicant: The Regents of the University of California
    Inventor: Boris C. Bastian