Abstract: Aspects of the disclosure relate to methods, systems, and computer-readable storage media, that are useful for characterizing subjects having cancer. The disclosure is based, in part, on methods for immunoprofiling a cancer subject and the subject's prognosis and/or likelihood of responding to an immunotherapy based upon analysis of leukocyte populations in the peripheral blood of the subject.

Abstract: Aspects of the disclosure relate to methods, systems, and computer-readable storage media, that are useful for characterizing subjects having cancer. The disclosure is based, in part, on methods for immunoprofiling a cancer subject and the subject's prognosis and/or likelihood of responding to an immunotherapy based upon analysis of leukocyte populations in the peripheral blood of the subject.

Abstract: Systems and methods for rapidly and reliably determining an arch width of a patient's dental arch. A three-dimensional (3D) model of a patient's teeth, including a target tooth, can be received. Dental features from the 3D model may be extracted. The dental features may include a point of intersection between an occlusal surface of a tooth and a long axis of the tooth. An arch width between the target tooth and an opposing tooth may be determined based on the extracted dental features.

Abstract: Various embodiments relating to synchronizing changes to a shared list of items between different devices are provided. In one embodiment, a first set of change operations for a first version of a shared list may be received from a first device. The first set of change operations may be performed on the first version of the shared list to produce a second version of the shared list. A second set of change operations for the first version of the shared list may be received from a second device. The second set of change operations may be performed on the second version of the shared list to produce a third version of the shared list that maintains changes that are made by the first set of change operations but that are not made by the second set of change operations.

Abstract: Various embodiments relating to managing media content availability in a playlist are provided. In one embodiment a playlist including a plurality of media content items may be received. Media content items included in the playlist that are not accessible due to a lack of access rights may be identified as inaccessible media content items. For each inaccessible media content item, if a different version of that inaccessible media content item is available as an accessible media content item, that inaccessible media content item may be replaced with the accessible media content item in the playlist.

Abstract: Various embodiments relating to synchronizing changes to a shared list of items between different devices are provided. In one embodiment, a first set of change operations for a first version of a shared list may be received from a first device. The first set of change operations may be performed on the first version of the shared list to produce a second version of the shared list. A second set of change operations for the first version of the shared list may be received from a second device. The second set of change operations may be performed on the second version of the shared list to produce a third version of the shared list that maintains changes that are made by the first set of change operations but that are not made by the second set of change operations.

Abstract: The invention is transgenic mice substantially all of whose cells contain a mutated human collagen gene. Methods for testing therapies for the treatment of osteogenesis imperfecta, osteoporosis, and chondrodysplasia are provided.