Abstract: The present invention discloses a capsule configured for controllably remaining within a patient's body for a certain period of time as well as a system comprising the capsule thereof. The invention also discloses a capsule being configured and operable for electrical stimulation, as well as a system comprising the capsule thereof.

Abstract: A capsule to be ingested by a subject, the capsule may include an outer enclosure configured to dissolve in gastric juice; a secondary enclosure that is permeable for gastric juice, is at least partially surrounded by the outer enclosure when in a folded state, and has a fully expanded volume; and an expandable polymer element that is surrounded by the secondary enclosure; wherein a fully expanded volume of the expandable polymer element exceeds the fully expanded volume of the secondary enclosure.

Abstract: A gastrointestinal stimulation system includes a remote controlled capsule adapted for positioning in the gastrointestinal tract (GT) of a patient, in which the capsule is secured to the inner wall of the gastrointestinal tract (GT) of a patient by a magnetic coupling system. The capsule is configured to activate at least one chosen area of the patient's GI tract, including when desired, the vagus nerve, thereby facilitating gastro motility or having other interaction with the GI tract, such as monitoring thereof. The remote controlled capsule also may be configured to activate patient's lower esophageal sphincter (LES), stimulating the LES muscle and restoring the barrier between the stomach and the esophagus for treatment of Gastroesophageal reflux disease (GERD). The capsule also may be inserted to the anal canal for treatment of constipation.

Abstract: A gastrointestinal stimulation system includes a remote controlled capsule adapted for positioning in the gastrointestinal tract (GT) of a patient, in which the capsule is secured to the inner wall of the gastrointestinal tract (GT) of a patient by a magnetic coupling system. The capsule is configured to activate at least one chosen area of the patient's GI tract, including when desired, the vagus nerve, thereby facilitating gastro motility or having other interaction with the GI tract, such as monitoring thereof. The remote controlled capsule also may be configured to activate patient's lower esophageal sphincter (LES), stimulating the LES muscle and restoring the barrier between the stomach and the esophagus for treatment of Gastroesophageal reflux disease (GERD). The capsule also may be inserted to the anal canal for treatment of constipation.

Abstract: A physiotherapeutic device for concurrently applying heat and electrical stimulation to a localized treatment area comprises a heat transfer medium for placing in contact with the treatment area, the heat transfer medium having a heat capacity such that the device is operable to change a temperature of said heat transfer medium from a temperature able to induce a burn to a safe temperature substantially within a minute.

Abstract: A physiotherapeutic device for concurrently applying heat and electrical stimulation to a localized treatment area, the device comprising a heat transfer medium for placing in contact with said treatment area, said heat transfer medium having a heat capacity such that said device is operable to change a temperature of said heat transfer medium from a temperature able to induce a burn to a safe temperature substantially within a minute.