Patents by Inventor Brad Dykstra

Brad Dykstra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for Drug Delivery and Methods of Use Thereof
    Publication number: 20210252070
    Abstract: Methods for producing megakaryocytes and platelets derived from inducible pluripotent stem cells and comprising a therapeutic agent are provided. The present disclosure further provides methods and compositions for loading a platelet or a megakaryocyte with a therapeutic agent and for genetically modifying a platelet or a megakaryocyte to express an agent.
    Type: Application
    Filed: June 29, 2019
    Publication date: August 19, 2021
    Inventors: Jonathan N. Thon, Brad Dykstra, Brenden William Smith
  • Compositions and Methods for Producing Megakaryocytes
    Publication number: 20210054336
    Abstract: Methods for producing megakaryocytic progenitors (preMKs) and megakaryocytes (MKs) from stem cells are provided. The present disclosure further provides compositions comprising preMKs and MKs and their lysates, and also methods of use of preMKs, MKs, their lysates and compositions thereof.
    Type: Application
    Filed: January 5, 2019
    Publication date: February 25, 2021
    Inventors: Jonathan Thon, Brad Dykstra
  • Compositions for Drug Delivery and Methods of Use Thereof
    Publication number: 20200138868
    Abstract: Methods for producing megakaryocytes and platelets derived from inducible pluripotent stem cells are provided. Such megakaryocytes or platelets can be genetically modified to comprise a nucleic acid molecule encoding a therapeutic agent. The present disclosure further provides methods and compositions for loading a platelet or a megakaryocyte with a therapeutic agent and for genetically modifying a platelet or a megakaryocyte to express an agent.
    Type: Application
    Filed: December 30, 2019
    Publication date: May 7, 2020
    Applicant: Platelet Biogenesis, Inc.
    Inventors: Jonathan N. Thon, Brad Dykstra, Brenden William Smith, Christian Gerald Peters, Thomas Carl Schulz