Patents by Inventor Bradd N. Picone

Bradd N. Picone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF
    Publication number: 20230106943
    Abstract: Provided in this disclosure are pharmaceutical formulations comprising antimicrobial peptides with enhanced stability. Further provided herein are methods of treating or preventing an infection comprising administering pharmaceutical formulations comprising antimicrobial peptides when administered to a subject.
    Type: Application
    Filed: April 26, 2022
    Publication date: April 6, 2023
    Inventors: Jonathan D. STECKBECK, Bradd N. PICONE, Despina X. DOBBINS
  • Meniscal repair adhesive
    Patent number: 11433162
    Abstract: A composition that includes (a) a prepolymer having at least one free isocyanate group that is capable of bonding to tissue and that cures in vivo upon exposure to water to form a polymer having a compressive modulus between 1.9 and 14.4 MPa and a tensile modulus between 5.0 and 30, and (b) an oil that is miscible in the prepolymer, the oil being selected from the group consisting of silicone oils, mineral oil, vegetable oils, and combinations thereof. The composition retains its integrity when delivered in an aqueous medium.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: September 6, 2022
    Assignee: ARTHREX, INC.
    Inventors: Dottie M. Clower, Eric J. Beckman, Bradd N. Picone
  • MENISCAL REPAIR ADHESIVE
    Publication number: 20210038761
    Abstract: A composition that includes (a) a prepolymer having at least one free isocyanate group that is capable of bonding to tissue and that cures in vivo upon exposure to water to form a polymer having a compressive modulus between 1.9 and 14.4 MPa and a tensile modulus between 5.0 and 30, and (b) an oil that is miscible in the prepolymer, the oil being selected from the group consisting of silicone oils, mineral oil, vegetable oils, and combinations thereof. The composition retains its integrity when delivered in an aqueous medium.
    Type: Application
    Filed: October 26, 2020
    Publication date: February 11, 2021
    Applicant: ARTHTEX, INC.
    Inventors: Dottie M. CLOWER, Eric J. BECKMAN, Bradd N. PICONE
  • Meniscal repair adhesive
    Patent number: 10850005
    Abstract: A composition that includes (a) a prepolymer having at least one free isocyanate group that is capable of bonding to tissue and that cures in vivo upon exposure to water to form a polymer having a compressive modulus between 1.9 and 14.4 MPa and a tensile modulus between 5.0 and 30, and (b) an oil that is miscible in the prepolymer, the oil being selected from the group consisting of silicone oils, mineral oil, vegetable oils, and combinations thereof. The composition retains its integrity when delivered in an aqueous medium.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: December 1, 2020
    Assignee: ARTHREX, INC.
    Inventors: Dottie M. Clower, Eric J. Beckman, Bradd N. Picone
  • Meniscal Repair Adhesive
    Publication number: 20200085998
    Abstract: A composition that includes (a) a prepolymer having at least one free isocyanate group that is capable of bonding to tissue and that cures in vivo upon exposure to water to form a polymer having a compressive modulus between 1.9 and 14.4 MPa and a tensile modulus between 5.0 and 30, and (b) an oil that is miscible in the prepolymer, the oil being selected from the group consisting of silicone oils, mineral oil, vegetable oils, and combinations thereof. The composition retains its integrity when delivered in an aqueous medium.
    Type: Application
    Filed: April 29, 2019
    Publication date: March 19, 2020
    Inventors: Dottie M. Clower, Eric J. Beckman, Bradd N. Picone
  • Meniscal Repair Adhesive
    Publication number: 20170056549
    Abstract: A composition that includes (a) a prepolymer having at least one free isocyanate group that is capable of bonding to tissue and that cures in vivo upon exposure to water to form a polymer having a compressive modulus between 1.9 and 14.4 MPa and a tensile modulus between 5.0 and 30, and (b) an oil that is miscible in the prepolymer, the oil being selected from the group consisting of silicone oils, mineral oil, vegetable oils, and combinations thereof. The composition retains its integrity when delivered in an aqueous medium.
    Type: Application
    Filed: August 31, 2016
    Publication date: March 2, 2017
    Inventors: Dottie M. Clower, Eric J. Beckman, Bradd N. Picone