Patents by Inventor Bradley D. Smith

Bradley D. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240125232
    Abstract: A cutter head includes a first member, a cutting bit, and a second member. The first member includes a first end and a second end and includes a first mass. The cutting bit is coupled to the first member proximate the second end. The cutting bit includes a cutting edge rotatable about the axis. The second member is rotatable about the axis and includes a second mass eccentrically positioned with respect to the axis. Rotation of the second mass causes the first member and the cutting bit to oscillate.
    Type: Application
    Filed: July 10, 2023
    Publication date: April 18, 2024
    Inventors: Russell P. Smith, Andrew D. Hunter, Peter A. Lugg, Ian B. Schirmer, Geoffrey W. Keech, Christopher Coates, Bradley M. Neilson
  • Patent number: 11931312
    Abstract: A therapy system includes a patient support apparatus and a pneumatic therapy device that is coupleable to the patient support apparatus. The therapy device may receive power and air flow from the patient support apparatus.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: March 19, 2024
    Assignee: Hill-Rom Services, Inc.
    Inventors: Eric D. Benz, John G. Byers, Scott M. Corbin, Richard H. Heimbrock, Michael A. Knecht, Bradley T. Smith, Lori Ann Zapfe, Robert M. Zerhusen, Kenneth L. Lilly, Jonathan D. Turner, James L. Walke, Joseph T. Canter, Richard J. Schuman, Sr., John V. Harmeyer
  • Publication number: 20230219933
    Abstract: The near-infrared window of fluorescent heptamethine cyanine dyes greatly facilitates biological imaging because there is deep penetration of the light and negligible background fluorescence. But dye instability, aggregation, and poor pharmacokinetics are current drawbacks that limit performance and the scope of possible applications. All these limitations are simultaneously overcome with a new molecular design strategy that produces a charge balanced and sterically shielded fluorochrome. The key design feature is a meso-Aryl group that simultaneously projects two shielding arms directly over each face of a linear heptamethine polyene. Cell and mouse imaging experiments compared a shielded heptamethine cyanine dye (and several peptide and antibody bioconjugates) to benchmark heptamethine dyes and found that the shielded systems possess an unsurpassed combination of photophysical, physiochemical and biodistribution properties that greatly enhance bioimaging performance.
    Type: Application
    Filed: February 22, 2021
    Publication date: July 13, 2023
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Bradley D. Smith, Donghao Li
  • Publication number: 20210215276
    Abstract: A one-piece exterior molding for controlling routing of an underlying hose can comprise a plurality of rings that extend in spaced relationship in a length direction of the exterior molding, and at least two spannings that run in the length direction of the exterior molding from a first end portion of the exterior molding to a second end portion of the exterior molding opposite the first end portion. The at least two spannings can be spaced from each other radially, according to different radii extending from a central axis of the exterior molding. The exterior molding is configured to control routing of the underlying hose according to straight and/or one or more curves based on configuration of the plurality of rings and the at least two spannings.
    Type: Application
    Filed: January 13, 2020
    Publication date: July 15, 2021
    Applicant: Caterpillar Inc.
    Inventor: Bradley D. Smith
  • Patent number: 10683174
    Abstract: A flow-through discharge assembly having a rotatable tube section and an opening through which product is discharged and a positioning apparatus for rotating the tube section between operation and non-operational conditions. When the tube is positioned in an operational orientation, grain exits through the opening for discharge from the assembly. When the tube is returned to a non-operational condition, the tube opening is blocked and grain is prevented from exiting through the opening. The tube opening may be a single elongated opening or may include multiple tube openings through which product is discharged. A method of using a rotary discharge assembly to control grain flow within a grain handling system is also disclosed.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: June 16, 2020
    Assignee: AG GROWTH INTERNATIONAL INC.
    Inventors: Jeremy J. Huff, Douglas Kruse, Michael Patenaude, Bradley D. Smith
  • Publication number: 20180282067
    Abstract: A flow-through discharge assembly having a rotatable tube section and an opening through which product is discharged and a positioning apparatus for rotating the tube section between operation and non-operational conditions. When the tube is positioned in an operational orientation, grain exits through the opening for discharge from the assembly. When the tube is returned to a non-operational condition, the tube opening is blocked and grain is prevented from exiting through the opening. The tube opening may be a single elongated opening or may include multiple tube openings through which product is discharged. A method of using a rotary discharge assembly to control grain flow within a grain handling system is also disclosed.
    Type: Application
    Filed: March 31, 2017
    Publication date: October 4, 2018
    Applicant: Global Industries, Incorporated
    Inventors: Jeremy J. Huff, Douglas Kruse, Michael Patenaude, Bradley D. Smith
  • Patent number: 9174590
    Abstract: A system for coupling a trim component to a body component having a bearing surface. The system has a threaded weld fastener coupled to the body. The trim piece has an exterior bearing surface and an interior bearing surface. Defined within the trim piece is an aperture having a lead-in portion. A rotatable fastener having a nut body with a cylindrical body portion is floatably positioned within the aperture. The body defines a fastener holding aperture and defines a side slot.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: November 3, 2015
    Assignee: NEWFREY LLC
    Inventors: Bradley D. Smith, Jason A. Meyers, Mark H. Delcourt, Sean Tomaselli
  • Publication number: 20130272778
    Abstract: A system for coupling a trim component to a body component having a bearing surface. The system has a threaded weld fastener coupled to the body. The trim piece has an exterior bearing surface and an interior bearing surface. Defined within the trim piece is an aperture having a lead-in portion. A rotatable fastener having a nut body with a cylindrical body portion is floatably positioned within the aperture. The body defines a fastener holding aperture and defines a side slot.
    Type: Application
    Filed: April 17, 2012
    Publication date: October 17, 2013
    Applicant: Newfrey LLC
    Inventors: Bradley D. Smith, Jason A. Meyers, Mark H. Delcourt, Sean Tomaselli
  • Patent number: 8389223
    Abstract: Embodiments of the present invention are generally directed to compositions comprising a class of molecular probes for detecting the presence of anionic cell surfaces. Embodiments include compositions that are enriched for these compositions and preparations, particularly preparations suitable for use as laboratory/clinical reagents and diagnostic indicators, either alone or as part of a kit. An embodiment of the invention provides for a highly selective agent useful in the discernment and identification of dead or dying cells, such as apoptotic cells, in a relatively calcium-free environment. An embodiment of the invention provides a selective agent for the identification of bacteria in a mixed population of bacterial cells and nonbacterial cells.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: March 5, 2013
    Assignee: University of Notre Dame du Lac
    Inventor: Bradley D. Smith
  • Publication number: 20100331542
    Abstract: Embodiments of the present invention are generally directed to compositions comprising a class of molecular probes for detecting the presence of anionic cell surfaces. Embodiments include compositions that are enriched for these compositions and preparations, particularly preparations suitable for use as laboratory/clinical reagents and diagnostic indicators, either alone or as part of a kit. An embodiment of the invention provides for a highly selective agent useful in the discernment and identification of dead or dying cells, such as apoptotic cells, in a relatively calcium-free environment. An embodiment of the invention provides a selective agent for the identification of bacteria in a mixed population of bacterial cells and nonbacterial cells.
    Type: Application
    Filed: September 2, 2010
    Publication date: December 30, 2010
    Applicant: University of Notre Dame Du Lac
    Inventor: Bradley D. Smith
  • Publication number: 20100207001
    Abstract: A clamp includes polymeric body portions connected by a living hinge. A retention section is each created in each body portion. Elastically deflectable material insert members have injection molded features adapted to engage to the retention sections. An electrically conductive material is included with the elastically deflectable material to render the clamp electrically conductive.
    Type: Application
    Filed: February 13, 2009
    Publication date: August 19, 2010
    Applicant: Newfrey LLC
    Inventors: Bradley D. Smith, Terri L. Wernert, Roger E. Pilon, Michael E. Hozdish
  • Patent number: 7614125
    Abstract: A positive hold tube weld stud assembly connectable to a vehicle body panel includes a substantially hollow tubular-shaped body. The body includes an inner body wall defined by a body internal aperture. A raised engagement portion extends inwardly from the inner body wall. A first chamfer positioned proximate an end surface of the body transitions between the inner body wall and the raised engagement portion. A second chamfer transitions between the raised engagement portion and the inner body wall. An insert is partially received in the body internal aperture and is adapted to engage a body connectable device. The insert includes a chamfered stud engagement portion releasably engageable with the second chamfer in an insert installed position.
    Type: Grant
    Filed: August 7, 2006
    Date of Patent: November 10, 2009
    Assignee: Newfrey LLC
    Inventors: Mark H. Delcourt, Bradley D. Smith
  • Publication number: 20080171351
    Abstract: Embodiments of the present invention are generally directed to compositions comprising a class of molecular probes for detecting the presence of anionic cell surfaces. Embodiments include compositions that are enriched for these compositions and preparations, particularly preparations suitable for use as laboratory/clinical reagents and diagnostic indicators, either alone or as part of a kit. An embodiment of the invention provides for a highly selective agent useful in the discernment and identification of dead or dying cells, such as apoptotic cells, in a relatively calcium-free environment. An embodiment of the invention provides a selective agent for the identification of bacteria in a mixed population of bacterial cells and nonbacterial cells.
    Type: Application
    Filed: May 16, 2007
    Publication date: July 17, 2008
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventor: Bradley D. Smith
  • Publication number: 20080029582
    Abstract: A positive hold tube weld stud assembly connectable to a vehicle body panel includes a substantially hollow tubular-shaped body. The body includes an inner body wall defined by a body internal aperture. A raised engagement portion extends inwardly from the inner body wall. A first chamfer positioned proximate an end surface of the body transitions between the inner body wall and the raised engagement portion. A second chamfer transitions between the raised engagement portion and the inner body wall. An insert is partially received in the body internal aperture and is adapted to engage a body connectable device. The insert includes a chamfered stud engagement portion releasably engageable with the second chamfer in an insert installed position.
    Type: Application
    Filed: August 7, 2006
    Publication date: February 7, 2008
    Inventors: Mark H. Delcourt, Bradley D. Smith
  • Patent number: 7179616
    Abstract: The present invention relates generally to a method and compound for sensing the presence of anionic phospholipids, especially phosphatidylserine, on the surface of vesicles and cells.
    Type: Grant
    Filed: September 8, 2003
    Date of Patent: February 20, 2007
    Assignee: University of Notre Dame du Lac
    Inventor: Bradley D. Smith
  • Patent number: 5800624
    Abstract: Plasticized liquid membranes and processes for separating monosaccharides from disaccharides and from other monosaccharides employing the membranes are provided. Fructose is separated from glucose via the membrane process to provide fructose in concentrations sufficient for HFS (high fructose syrup) and sucrose, glucose and fructose are separated from crude sources such as molasses, sugar cane juice and beet sugar juice. The plasticized membranes are prepared by dissolving a lipophilic polymer such as cellulose triacetate, an organic liquid plasticizer such as a hydrophobic ether compound e.g. 2-nitrophenyloctyl ether and, a carrier compound such as a quaternary ammonium salt or a boronic acid compound with lipophilic substitution in a suitable solvent which upon evaporation provides the plasticized membrane. The membrane produced is homogeneous having all three components equally dispersed in the membrane.
    Type: Grant
    Filed: October 22, 1996
    Date of Patent: September 1, 1998
    Assignee: University of Notre Dame
    Inventors: Bradley D. Smith, Jennifer A. Riggs