Patents by Inventor Bradley David Olsen

Bradley David Olsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11939408
    Abstract: Skin hydration is necessary to maintain the epidermal barrier, minimize adverse environmental influences, and reduce cell stress. Provided herein are compounds, such as compounds of Formula (I), and pharmaceutically and cosmetically acceptable salts thereof, and compositions, methods, and uses that may be used for skin hydration. Also reported herein is a scalable method for synthesizing compounds of Formula (I). The compounds provided herein are responsible for improved skin penetration and/or retention and are therefore useful for the treatment and/or prevention of various diseases, disorders, or conditions to protect human skin.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: March 26, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Bradley David Olsen, Allie Obermeyer, Sieun Kim Barnes, Yun Jung Yang
  • Patent number: 11598769
    Abstract: The present disclosure relates to protein-polymer conjugates comprising an engineered binding oligomer protein and a polymer for detection of a ligand of interest, methods, compositions and kits thereof.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: March 7, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Bradley David Olsen, Hadley Sikes Johnson, Eric Alexander Miller, Justin Paloni
  • Patent number: 11066557
    Abstract: Disclosed are copolymers comprising a modified protein first monomer, a surfactant, and a second monomer. Methods of making copolymers comprising a modified protein first monomer, a surfactant, and a second monomer are described. Also disclosed are articles comprising the copolymers. Disclosed are blends comprising a protein, a surfactant, and a second monomer. Methods of making blends comprising a protein, a surfactant, and a second monomer are described. Also disclosed are articles comprising the blends.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: July 20, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Bradley David Olsen, Wui Yarn Chan
  • Publication number: 20210189018
    Abstract: Skin hydration is necessary to maintain the epidermal barrier, minimize adverse environmental influences, and reduce cell stress. Provided herein are compounds, such as compounds of Formula (I), and pharmaceutically and cosmetically acceptable salts thereof, and compositions, methods, and uses that may be used for skin hydration. Also reported herein is a scalable method for synthesizing compounds of Formula (I). The compounds provided herein are responsible for improved skin penetration and/or retention and are therefore useful for the treatment and/or prevention of various diseases, disorders, or conditions to protect human skin.
    Type: Application
    Filed: December 18, 2020
    Publication date: June 24, 2021
    Applicants: Massachusetts Institute of Technology, Revlon Consumer Products Corporation
    Inventors: Bradley David Olsen, Allie Obermeyer, Sieun Kim Barnes, Lavinia Popescu, Yun Jung Yang
  • Publication number: 20200057058
    Abstract: The present disclosure relates to protein-polymer conjugates comprising an engineered binding oligomer protein and a polymer for detection of a ligand of interest, methods, compositions and kits thereof.
    Type: Application
    Filed: July 26, 2019
    Publication date: February 20, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Bradley David Olsen, Hadley Sikes Johnson, Eric Alexander Miller, Justin Paloni
  • Publication number: 20190314260
    Abstract: Disclosed herein are engineered constructs that have keratin-binding functionality, and uses thereof for hair treatment.
    Type: Application
    Filed: April 12, 2019
    Publication date: October 17, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: Bradley David Olsen, Sieun Kim
  • Publication number: 20190062556
    Abstract: Disclosed are copolymers comprising a modified protein first monomer, a surfactant, and a second monomer. Methods of making copolymers comprising a modified protein first monomer, a surfactant, and a second monomer are described. Also disclosed are articles comprising the copolymers. Disclosed are blends comprising a protein, a surfactant, and a second monomer. Methods of making blends comprising a protein, a surfactant, and a second monomer are described. Also disclosed are articles comprising the blends.
    Type: Application
    Filed: August 21, 2018
    Publication date: February 28, 2019
    Inventors: Bradley David Olsen, Wui Yarn Chan
  • Patent number: 10034958
    Abstract: Provided herein are hemostatic compositions useful for treating wounds in a patient in need thereof. An exemplary hemostatic comprises gelatin or a derivative thereof and silicate nanoparticles. Methods of use, kits comprising the compositions, and a process of making the compositions are also provided.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: July 31, 2018
    Assignees: The Brigham and Women's Hospital, Inc., Massachusetts Institute of Technology
    Inventors: Akhilesh K. Gaharwar, Reginald Keith Avery, Gareth H. McKinley, Alireza Khademhosseini, Bradley David Olsen
  • Publication number: 20160144068
    Abstract: Provided herein are hemostatic compositions useful for treating wounds in a patient in need thereof. An exemplary hemostatic comprises gelatin or a derivative thereof and silicate nanoparticles. Methods of use, kits comprising the compositions, and a process of making the compositions are also provided.
    Type: Application
    Filed: June 19, 2014
    Publication date: May 26, 2016
    Applicants: The Brigham and Women's Hospital, Inc., Massachusetts Institute of Technology
    Inventors: Akhilesh K. Gaharwar, Reginald Keith Avery, Gareth H. McKinley, Alireza Khademhosseini, Bradley David Olsen