Patents by Inventor Bradley S. Thomas
Bradley S. Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200121863Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and aasures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.Type: ApplicationFiled: December 20, 2019Publication date: April 23, 2020Applicant: Becton, Dickinson and CompanyInventors: Michael R. Walters, Bradley S. Thomas, Katherine Stanton
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Patent number: 10549049Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.Type: GrantFiled: September 28, 2015Date of Patent: February 4, 2020Assignee: Becton, Dickinson and CompanyInventors: Michael R. Walters, Bradley S. Thomas, Katherine Stanton
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Patent number: 9696328Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: GrantFiled: July 18, 2012Date of Patent: July 4, 2017Assignee: Becton, Dickinson and CompanyInventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Publication number: 20160015906Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.Type: ApplicationFiled: September 28, 2015Publication date: January 21, 2016Applicant: BECTON, DICKINSON AND COMPANYInventors: Michael R. Walters, Bradley S. Thomas, Katherine Stanton
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Patent number: 9234236Abstract: A microfluidic chip includes microfluidic channels, elements for thermally and optically isolating the microfluidic channels, and elements for enhancing the detection of optical signal emitted from the microfluidic channels. The thermal and optical isolation elements may comprise barrier channels interposed between adjacently-arranged pairs of microfluidic channels for preventing thermal and optical cross-talk between the adjacent microfluidic channels. The isolation element may alternatively comprise reflective film embedded in the microfluidic chip between the adjacent microfluidic channels. The signal enhancement elements comprise structures disposed adjacent to the microfluidic channels that reflect light passing through or emitted from the microfluidic channel in a direction toward a detector. The structures may comprise channels or a faceted surface that redirects the light by total internal reflection or reflective film material embedded in the microfluidic chip.Type: GrantFiled: October 7, 2014Date of Patent: January 12, 2016Assignee: Canon U.S. Life Sciences, Inc.Inventors: Bradley S. Thomas, Johnathan S. Coursey, Kenton C. Hasson, Hongye Liang
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Patent number: 9180257Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.Type: GrantFiled: September 30, 2010Date of Patent: November 10, 2015Assignee: Becton, Dickinson and CompanyInventors: Michael R. Walters, Bradley S. Thomas, Katherine Stanton
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Publication number: 20150118738Abstract: A microfluidic chip includes microfluidic channels, elements for thermally and optically isolating the microfluidic channels, and elements for enhancing the detection of optical signal emitted from the microfluidic channels. The thermal and optical isolation elements may comprise barrier channels interposed between adjacently-arranged pairs of microfluidic channels for preventing thermal and optical cross-talk between the adjacent microfluidic channels. The isolation element may alternatively comprise reflective film embedded in the microfluidic chip between the adjacent microfluidic channels. The signal enhancement elements comprise structures disposed adjacent to the microfluidic channels that reflect light passing through or emitted from the microfluidic channel in a direction toward a detector. The structures may comprise channels or a faceted surface that redirects the light by total internal reflection or reflective film material embedded in the microfluidic chip.Type: ApplicationFiled: October 7, 2014Publication date: April 30, 2015Applicant: Canon U.S. Life Sciences, Inc.Inventors: Bradley S. Thomas, Johnathan S. Coursey, Kenton C. Hasson, Hongye Liang
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Patent number: 8852527Abstract: A microfluidic chip includes microfluidic channels, elements for thermally and optically isolating the microfluidic channels, and elements for enhancing the detection of optical signal emitted from the microfluidic channels. The thermal and optical isolation elements may comprise barrier channels interposed between adjacently-arranged pairs of microfluidic channels for preventing thermal and optical cross-talk between the adjacent microfluidic channels. The isolation element may alternatively comprise reflective film embedded in the microfluidic chip between the adjacent microfluidic channels. The signal enhancement elements comprise structures disposed adjacent to the microfluidic channels that reflect light passing through or emitted from the microfluidic channel in a direction toward a detector. The structures may comprise channels or a faceted surface that redirects the light by total internal reflection or reflective film material embedded in the microfluidic chip.Type: GrantFiled: November 12, 2012Date of Patent: October 7, 2014Assignee: Canon U.S. Life Sciences, Inc.Inventors: Bradley S. Thomas, Johnathan S. Coursey, Kenton C. Hasson, Hongye Liang
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Patent number: 8329117Abstract: A microfluidic chip includes microfluidic channels, elements for thermally and optically isolating the microfluidic channels, and elements for enhancing the detection of optical signal emitted from the microfluidic channels. The thermal and optical isolation elements may comprise barrier channels interposed between adjacently-arranged pairs of microfluidic channels for preventing thermal and optical cross-talk between the adjacent microfluidic channels. The isolation element may alternatively comprise reflective film embedded in the microfluidic chip between the adjacent microfluidic channels. The signal enhancement elements comprise structures disposed adjacent to the microfluidic channels that reflect light passing through or emitted from the microfluidic channel in a direction toward a detector. The structures may comprise channels or a faceted surface that redirects the light by total internal reflection or reflective film material embedded in the microfluidic chip.Type: GrantFiled: May 13, 2010Date of Patent: December 11, 2012Assignee: Canon U.S. Life Sciences, Inc.Inventors: Bradley S. Thomas, Johnathan S. Coursey, Kenton C. Hasson, Hongye Liang
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Publication number: 20120282603Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: ApplicationFiled: July 18, 2012Publication date: November 8, 2012Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Patent number: 8002756Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.Type: GrantFiled: November 30, 2007Date of Patent: August 23, 2011Assignee: Becton, Dickinson and CompanyInventors: Michael R. Walters, Bradley S. Thomas, Katherine Stanton
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Publication number: 20110200991Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: ApplicationFiled: April 26, 2011Publication date: August 18, 2011Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Publication number: 20110064628Abstract: A microfluidic chip includes microfluidic channels, elements for thermally and optically isolating the microfluidic channels, and elements for enhancing the detection of optical signal emitted from the microfluidic channels. The thermal and optical isolation elements may comprise barrier channels interposed between adjacently-arranged pairs of microfluidic channels for preventing thermal and optical cross-talk between the adjacent microfluidic channels. The isolation element may alternatively comprise reflective film embedded in the microfluidic chip between the adjacent microfluidic channels. The signal enhancement elements comprise structures disposed adjacent to the microfluidic channels that reflect light passing through or emitted from the microfluidic channel in a direction toward a detector. The structures may comprise channels or a faceted surface that redirects the light by total internal reflection or reflective film material embedded in the microfluidic chip.Type: ApplicationFiled: May 13, 2010Publication date: March 17, 2011Applicant: Canon U.S. Life Sciences, Inc.Inventors: Bradley S. THOMAS, Johnathan S. Coursey, Kenton C. Hasson, Hongye Liang
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Publication number: 20110022006Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.Type: ApplicationFiled: September 30, 2010Publication date: January 27, 2011Inventors: Michael R. Walters, Bradley S. Thomas, Katherine Stanton
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Publication number: 20090155808Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: ApplicationFiled: February 11, 2009Publication date: June 18, 2009Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Publication number: 20090082734Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.Type: ApplicationFiled: November 30, 2007Publication date: March 26, 2009Applicant: BECTON, DICKINSON AND COMPANYInventors: Michael R. Walters, Bradley S. Thomas, Katherine Stanton
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Publication number: 20040029260Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: ApplicationFiled: May 19, 2003Publication date: February 12, 2004Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Publication number: 20030224371Abstract: An integrated cartridge for automated sample manipulation and, particularly strand displacement amplification, is provided. The cartridge comprises a sealed, two-part device with internal fluid channels and chambers, as well as reagents. The cartridge performs the sequence of fluid transfers, reagent additions and heat transitions, such as those of the strand displacement amplification process, in a single, sealed device.Type: ApplicationFiled: June 4, 2002Publication date: December 4, 2003Inventors: Bradley S. Thomas, Alan E. Harper, Charles E. Clemens, Raymond D. Clark, Robert J. Elms, Lanny Gorton, John B. Slate, Richard P. Meyst
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Publication number: 20020008053Abstract: A system and method for manipulating magnetic particles in a solution to separate nucleic acid molecules from cell components in a cell solution. The system and method employ a device capable of receiving a plurality of tubes, each of which contain respective sample and paramagnetic particles. The device includes heating and cooling devices to facilitate a lysing step to release the nucleic acid molecules from the cells in the cell solution. The device further includes moveable magnets which can be moved proximate to and away from the tube to hold the paramagnetic particles to which the nucleic acid molecules become bound, so that the molecule-bound particles can be separated from the remainder of the solution, and washed as appropriate. The system also employs an electromagnet which is capable of demagnetizing the particles to allow the particles to freely mix with solution, such as elution solutions which are used to unbind the molecules from the particles.Type: ApplicationFiled: September 21, 2001Publication date: January 24, 2002Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas
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Patent number: D988581Type: GrantFiled: December 2, 2020Date of Patent: June 6, 2023Assignee: IDEAL Industries Lighting LLCInventors: Jin Hong Lim, Mark Lackey, Rob Sanchez, Charles Draper, Daniel James Van Epps, Jr., Bradley S. Thomas, Marco Ma