Abstract: The invention relates to a method for controlling the movement of an Abrikosov vortex of an element consisting of a supraconductive material, a so-called supraconductive element, comprising a step of inhomogeneously heating the supraconductive element with the Abrikosov vortex in a heating zone in such a way as to move the Abrikosov vortex towards the heating zone.

Abstract: The present invention is related to a method of studying (i) binding reactions, (ii) dissociation reactions, (iii) competitive binding reactions, or (iv) association reactions between two or more molecules in a biological sample by means of super-resolution imaging, in which method the reaction as such causes an event that forms the basis for the identification and localization-based super-resolution microscopy of the reaction (FIG. 1a).

Abstract: Method and system for optical detection of nano-objects in a refracting medium. A nano-object (n_oi) and the refractive medium are illuminated (A) with a periodically amplitude modulated coherent electromagnetic heating wave (HB(?)), to generate a specified temperature and refractive index profile in the vicinity of the nano-object, and with a coherent electromagnetic probe wave (PB) to generate an emerging probe wave (EPB(?)) having at least one intensity component amplitude modulated by a beat at the modulation frequency of the coherent heating wave. The intensity component amplitude modulated by a beat is detected (C) in the emerging wave (EPB(?)), to distinguish and represent this nano-object in the refractive medium. The invention is useful in the detection of nano-objects in an industrial, physiological or intracellular medium.

Abstract: The invention relates to a method and a system for optical detection of nano-objects in a refracting medium. A nano-object (n_oi) and the refractive medium are illuminated (A) with a periodically amplitude modulated coherent electromagnetic heating wave (HB(?)), to generate a specified temperature and refractive index profile in the vicinity of the nano-object, and with a coherent electromagnetic probe wave (PB) to generate an emerging probe wave (EPB(?)) having at least one intensity component amplitude modulated by a beat at the modulation frequency of the coherent heating wave. The intensity component amplitude modulated by a beat is detected (C) in the emerging wave (EPB(?)), to distinguish and represent this nano-object in the refractive medium. Application to the detection of nano-objects in an industrial, physiological or intracellular medium.

Abstract: A controllable single-photon source having a single illuminated molecule in a condensed phase host is provided. The single molecule is illuminated with a pulse of radiation having a wavelength such that the molecule is excited to a vibrational state higher in energy than an associated excited electronic state. The molecule rapidly, incoherently and irreversibly decays, with a lifetime Tvib, from the vibrational state to the excited electronic state by transferring the corresponding vibrational energy to the host. The excited electronic state has a lifetime T, and with high probability the single molecule makes a radiative transition from this state to emit a single photon. The pump pulse duration Tp satisfies the condition Tvib<Tp<T. Room temperature operation and spectral separation of pump and single-photon radiation are thereby provided. A semiconductor nanocrystal can be used instead of a molecule.

Abstract: A method and device for photothermal imaging tiny metal particles which are immersed in a given medium like a living cell. The given medium and immersed tiny metal particles are illuminated through separate phase reference laser beam and sensitive probe laser beam, with the sensitive probe laser beam undergoing through impingement on the given medium slight phase changes induced by photothermal effect due to a local heating thanks to a heating laser beam, in the absence of any substantial phase changes to the phase reference laser beam. Illuminating is performed by focusing the separate phase reference laser beam. The induced slight phase changes on the sensitive probe laser beam with reference to the phase reference laser beam are detected through differential phase interference contrast phenomenon so as to allow each of the tiny metal particles in the given medium to be imaged as an optical label.

Abstract: A controllable single-photon source having a single illuminated molecule in a condensed phase host is provided. The single molecule is illuminated with a pulse of radiation having a wavelength such that the molecule is excited to a vibrational state higher in energy than an associated excited electronic state. The molecule rapidly, incoherently and irreversibly decays, with a lifetime Tvib, from the vibrational state to the excited electronic state by transferring the corresponding vibrational energy to the host. The excited electronic state has a lifetime T, and with high probability the single molecule makes a radiative transition from this state to emit a single photon. The pump pulse duration Tp satisfies the condition Tvib<Tp<T. Room temperature operation and spectral separation of pump and single-photon radiation are thereby provided. A semiconductor nanocrystal can be used instead of a molecule.

Abstract: A method and device for photothermal imaging tiny metal particles which are immersed in a given medium like a living cell deposited onto a transparent glass slide. The given medium and immersed tiny metal particles are illuminated through separate phase reference laser beam and sensitive probe laser beam, with the sensitive probe laser beam including a heating laser beam undergoing through impingement on the given medium slight phase changes induced by photothermal effect due to a local heating, in the absence of any substantial phase changes to the phase reference laser beam. Illuminating is performed by focusing the separate phase reference and sensitive probe laser beam through the transparent glass slide at a given depth within the given medium and a transmitted phase reference laser beam and a transmitted sensitive probe laser beam undergoing the slight phase changes are generated.

Abstract: A method and device for photothermal imaging tiny metal particles which are immersed in a given medium like a living cell. The given medium and immersed tiny metal particles are illuminated through separate phase reference laser beam and sensitive probe laser beam, with the sensitive probe laser beam undergoing through impingement on the given medium slight phase changes induced by photothermal effect due to a local heating thanks to a heating laser beam, in the absence of any substantial phase changes to the phase reference laser beam. Illuminating is performed by focusing the separate phase reference laser beam. The induced slight phase changes on the sensitive probe laser beam with reference to the phase reference laser beam are detected through differential phase interference contrast phenomenon so as to allow each of the tiny metal particles in the given medium to be imaged as an optical label.

Abstract: The present invention provides for the generation of a controllable source of single photons generated one at a time using optical pumping of a single molecule at room temperature. A single fluorescent molecule is pumped by a light source so that the molecule is placed in its electronic excited state with high probability. The molecule then de-excites via the emission of a single photon, which can be collected by a means for collecting. The room temperature source of single photons is far more convenient and therefore more widely applicable. A high probability of single-photon emission for each incident pump pulse is provided, a property which is useful for transmission of sensitive data bits by the methods of quantum cryptography.