Patents by Inventor Brahim Zadi

Brahim Zadi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of forming liposomes
    Patent number: 9675554
    Abstract: Compositions of reagents are formed by forming empty liposomes, mixing the thus-formed liposomes with a sugar solution and a regent, then drying the mixture. The compositions will generally contain less than 10% w/v sucrose. Using this procedure small liposomes are formed with high entrapment efficiency. The process is useful in the production of pharmaceuticals.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: June 13, 2017
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
    Inventors: Gregory Gregoriadis, Brahim Zadi, Pramukh N Jayasekera
  • Liposomes
    Patent number: 7025988
    Abstract: Liposomes containing lipophilic active ingredient are produced by dehydrating a mixture of liposomes, lipophilic active ingredient and sugar, usually followed by a rehydration step to form dehydration-rehydration vesicles. The lipophilic drug is suitably paclitaxel. The sugar is usually sucrose. The liposome forming compounds preferably include cholesterol and phosphatidylcholine, and optionally an anionic lipid. The ratio of sugar:lipid is preferably at least 5:1 w/w. The ratio of lipid:drug is preferably (up to 10):1 w/w.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: April 11, 2006
    Assignee: Lipoxen Technologies Limited
    Inventor: Brahim Zadi
  • Liposomes
    Publication number: 20030138481
    Abstract: Liposomes containing lipophilic active ingredient are produced by dehydrating a mixture of liposomes, lipophilic active ingredient and sugar, usually followed by a rehydration step to form dehydration-rehydration vesicles. The lipophilic drug is suitably paclitaxel. The sugar is usually sucrose. The liposome forming compounds preferably include cholesterol and phosphatidyl-choline, and optionally an anionic lipid. The ratio of sugar:lipid is preferably at least 5:1 w/w. The ratio of lipid:drug is preferably (up to 10):1 w/w.
    Type: Application
    Filed: October 7, 2002
    Publication date: July 24, 2003
    Inventor: Brahim Zadi