Patents by Inventor Brahma Singh

Brahma Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline polymorphic forms of monosodium n-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 11395809
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-V). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: July 26, 2022
    Assignee: NOVO NORDISK NORTH AMERICA OPERATIONS A/S
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20210177792
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-V). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: July 30, 2020
    Publication date: June 17, 2021
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 10744105
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: August 18, 2020
    Assignee: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20190343786
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: December 6, 2018
    Publication date: November 14, 2019
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Gastric Retention and Controlled Release Delivery System
    Publication number: 20190216729
    Abstract: The present invention relates to gastric retention delivery systems and controlled release compositions containing a pharmaceutically acceptable active agent and a delivery agent.
    Type: Application
    Filed: December 18, 2017
    Publication date: July 18, 2019
    Inventors: Jun Liao, Puchun Liu, Steven Dinh, Brahma Singh, Shingai Majuru, Prateek N. Bhargava
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 10188621
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: January 29, 2019
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20170326087
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: August 3, 2017
    Publication date: November 16, 2017
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 9750710
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: September 5, 2017
    Assignee: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20160184251
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: February 22, 2016
    Publication date: June 30, 2016
    Inventors: Halina LEVCHIK, Shingai MAJURU, Brahma SINGH, Jamila HARRIS
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 9321719
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: April 26, 2016
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20140187813
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: December 23, 2013
    Publication date: July 3, 2014
    Applicant: Emisphere Technologies, Inc.
    Inventors: Halina LEVCHIK, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 8636996
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: January 28, 2014
    Assignee: Emisphere Technologies, Inc
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Solid dosage form of wetted heparin
    Patent number: 8039018
    Abstract: The present invention relates to a solid pharmaceutical composition (such as a solid dosage form) comprising a delivery agent and wetted heparin. The inclusion of wetted heparin rather than un-wetted heparin in the solid pharmaceutical composition results in increased delivery of the heparin. Without being bound by any particular theory, applicants believe that because the polymer chain of the wetted heparin is already in an “open” form, while un-wetted heparin is not, less of the wetted heparin is broken down in the gastrointestinal tract and is more readily absorbed in the stomach.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: October 18, 2011
    Assignee: Emisphere Technologies, Inc.
    Inventors: Shingai Majuru, Brahma Singh, Nikhil Dhoot
  • Crystalline Polymorphic Forms Of Monosodium N-[-8-(2-Hydroxybenzoyl)Amino]Caprylate
    Publication number: 20090143330
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: May 6, 2005
    Publication date: June 4, 2009
    Applicant: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Gastric Retention and Controlled Release Delivery System
    Publication number: 20080153779
    Abstract: The present invention provice a device (FIG. 3) for providing communication through power lines (FIG. 2) comprised of multiple conductors by transmitting the data signals through a plurality of the conductors. One embodiment of the present invention comprises a transmit circuit communicatively coupled to a first conductor for applying the first voltage representing the data to the first energized conductor; the transmit circuit communicatively coupled to a second conductor for applying the second voltage representing the data to the second energized conductor; wherein the second voltage signal is opposite in polarity of the first voltage.
    Type: Application
    Filed: February 1, 2006
    Publication date: June 26, 2008
    Inventors: Jun Liao, Puchun Liu, Steven Dinh, Brahma Singh, Shingai Majuru, Prateek N. Bhargava, Nikhil Dhoot
  • Solid Dosage Form of Wetted Heparin
    Publication number: 20070224262
    Abstract: The present invention relates to a solid pharmaceutical composition (such as a solid dosage form) comprising a delivery agent and wetted heparin. The inclusion of wetted heparin rather than un-wetted heparin in the solid pharmaceutical composition results in increased delivery of the heparin. Without being bound by any particular theory, applicants believe that because the polymer chain of the wetted heparin is already in an “open” form, while un-wetted heparin is not, less of the wetted heparin is broken down in the gastrointestinal tract and is more readily absorbed in the stomach.
    Type: Application
    Filed: May 6, 2005
    Publication date: September 27, 2007
    Inventors: Shingai Majuru, Brahma Singh, Nikhil Dhoot