Abstract: The present invention generally relates to compositions and methods for treating or preventing an endoplasmic reticulum stress disorder in subjects, including compositions and methods for treating or preventing Wolfram syndrome. The present invention also relates to methods for treating symptoms of neurodegenerative diseases.

Abstract: A method involves presenting an interface which provides the ability to associate photographic images with an anatomical image for use in clinical documentation. A method involves presenting an interface which displays an anatomical image and lists both common conditions for selection by a user and common treatments for the presented or selected conditions. A method involves presenting an interface which displays an anatomical image providing drill down functionality.

Abstract: The present invention generally relates to compositions and methods for treating or preventing an endoplasmic reticulum stress disorder in subjects, including compositions and methods for treating or preventing Wolfram syndrome. The present invention also relates to methods for treating symptoms of neurodegenerative diseases.

Abstract: A method involves presenting an interface which provides the ability to associate photographic images with an anatomical image for use in clinical documentation. A method involves presenting an interface which displays an anatomical image and lists both common conditions for selection by a user and common treatments for the presented or selected conditions. A method involves presenting an interface which displays an anatomical image providing drill down functionality.

Abstract: A method involves presenting an interface which provides the ability to associate photographic images with an anatomical image for use in clinical documentation. A method involves presenting an interface which displays an anatomical image and lists both common conditions for selection by a user and common treatments for the presented or selected conditions. A method involves presenting an interface which displays an anatomical image providing drill down functionality.

Abstract: A dual-diaphragm loudspeaker driver assembly can include a multiple pole magnet structure, and first and second pole piece assemblies can be provided on opposite first and second sides of the multiple pole magnet structure. In an example, each pole piece assembly defines an airgap over a polarity transition region on a respective side of the magnet structure. First and second voice coils can be provided in respective ones of the airgaps, wherein each of the voice coils is coupled to a respective diaphragm assembly, and at least one acoustic tuning port can be configured to provide a damped acoustic communication path between first and opposite second sides of each diaphragm assembly.

Abstract: A dual-diaphragm loudspeaker driver assembly can include a multiple pole magnet structure, and first and second pole piece assemblies can be provided on opposite first and second sides of the multiple pole magnet structure. In an example, each pole piece assembly defines an airgap over a polarity transition region on a respective side of the magnet structure. First and second voice coils can be provided in respective ones of the airgaps, wherein each of the voice coils is coupled to a respective diaphragm assembly, and at least one acoustic tuning port can be configured to provide a damped acoustic communication path between first and opposite second sides of each diaphragm assembly.

Abstract: Complex collaboration or decision support applications perform complex design or planning tasks, often with the input of large groups of people over long periods of time. The combination of time and complexity can often obscure past actions, making it difficult to remember the factors that influenced earlier stages in the planning task. This is especially true if the task involves many people and different people work at different times. The application state navigation system provides an application-independent mechanism that allows operators to walk back through the history of the application in order to better understand (or remember) the application actions that were taken in the past and the triggers for those actions.

Abstract: A system and method for determining positions of multiple targets on a planar surface is described. The targets subject to detection may include a touch from a body part (such as a finger), a pen, or other objects. The system and method may use light sensors, such as cameras, to generate information for the multiple simultaneous targets (such as finger, pens, etc.) that are proximate to or on the planar surface. The information from the cameras may be used to generate possible targets. The possible targets include both “real” targets (a target associated with an actual touch) and “ghost” targets (a target not associated with an actual touch). Using analysis, such as a history of previous targets, the list of potential targets may then be narrowed to the multiple targets by analyzing state information for targets from a previous cycle (such as the targets determined during a previous frame).

Abstract: A system for distributed information processing and interaction includes a plurality of output devices arranged to produce a respective output portion of a system output, a plurality of application processors and a state server in data communication with the plurality of application processors. Each respective output portion is defined by context information. Each application processor is configured to process one or more respective application programs and is responsive to the context information. Each application processor is coupled with an associated respective output device for controlling the output device in producing the respective output portion. The state server provides the context information to the plurality of application processors. The architecture is extended to a more general system in which output devices produce a variety of outputs including device actuations, as well as video displays, and receive a variety of inputs.