Patents by Inventor Brandon L. Thompson

Brandon L. Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEVICES AND METHODS FOR EXTRACTION, SEPARATION AND THERMOCYCLING
    Publication number: 20220097042
    Abstract: A method to extract, amplify and separate nucleic acid in a microfluidic device having a plurality of chambers and channels can include a) introducing cells having nucleic acid to a first chamber of the microfluidic device and subjecting the cells in the first chamber to conditions that lyse the cells. The method can further include b) subjecting the first chamber to centrifugal force, thereby allowing the lysate or a portion thereof having nucleic acid to be distributed to a second chamber through a first channel in the microfluidic device. The method can also include c) combining the lysate or the portion thereof and reagents for amplification of the nucleic acid, thereby providing a second mixture. The method can also include d) subjecting the second chamber to centrifugal force, thereby allowing gas to be expelled from the second mixture.
    Type: Application
    Filed: September 7, 2021
    Publication date: March 31, 2022
    Inventors: James P. Landers, Jacquelyn A. DuVall, Delphine Le Roux, Brian Root, Daniel Mills, Daniel A. Nelson, An-chi Tsuei, Brandon L. Thompson, Jingyi Li, Christopher Birch
  • Devices and methods for extraction, separation and thermocycling
    Patent number: 11135583
    Abstract: A method to extract, amplify and separate nucleic acid in a microfluidic device having a plurality of chambers and channels can include a) introducing cells having nucleic acid to a first chamber of the microfluidic device and subjecting the cells in the first chamber to conditions that lyse the cells. The method can further include b) subjecting the first chamber to centrifugal force, thereby allowing the lysate or a portion thereof having nucleic acid to be distributed to a second chamber through a first channel in the microfluidic device. The method can also include c) combining the lysate or the portion thereof and reagents for amplification of the nucleic acid, thereby providing a second mixture. The method can also include d) subjecting the second chamber to centrifugal force, thereby allowing gas to be expelled from the second mixture.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: October 5, 2021
    Assignee: University of Virginia Patent Foundation
    Inventors: James P. Landers, Jacquelyn A. DuVall, Delphine Le Roux, Brian Root, Daniel Mills, Daniel A. Nelson, An-Chi Tsuei, Brandon L. Thompson, Jingyi Li, Christopher Birch
  • DEVICES AND METHODS FOR EXTRACTION, SEPARATION AND THERMOCYCLING
    Publication number: 20180304253
    Abstract: A method to extract, amplify and separate nucleic acid in a microfluidic device having a plurality of chambers and channels can include a) introducing cells having nucleic acid to a first chamber of the microfluidic device and subjecting the cells in the first chamber to conditions that lyse the cells. The method can further include b) subjecting the first chamber to centrifugal force, thereby allowing the lysate or a portion thereof having nucleic acid to be distributed to a second chamber through a first channel in the microfluidic device. The method can also include c) combining the lysate or the portion thereof and reagents for amplification of the nucleic acid, thereby providing a second mixture. The method can also include d) subjecting the second chamber to centrifugal force, thereby allowing gas to be expelled from the second mixture.
    Type: Application
    Filed: October 13, 2016
    Publication date: October 25, 2018
    Inventors: James P. Landers, Jacquelyn A. DuVall, Delphine Le Roux, Brian Root, Daniel MIlls, Daniel A. Nelson, An-chi Tsuei, Brandon L. Thompson, Jingyi Li, Christopher Birch