Patents by Inventor Brendan P. Orner

Brendan P. Orner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Defined surfaces of self-assembled monolayers and stem cells
    Patent number: 8642337
    Abstract: A method for the construction of arrays from self-assembling monolayers is described. The arrays have particular utility for the screening of peptides ligands that can foster the growth of cells in culture. This technique has been used to identify peptide ligands that foster the growth of human stem cells, which otherwise require an extracellular matrix in order to grow in an undifferentiated state. This also makes possible an assay to identify other such peptides.
    Type: Grant
    Filed: November 8, 2011
    Date of Patent: February 4, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Laura L. Kiessling, Ratmir Derda, Brendan P. Orner, James A. Thomson
  • DEFINED SURFACES OF SELF-ASSEMBLED MONOLAYERS AND STEM CELLS
    Publication number: 20120135518
    Abstract: A method for the construction of arrays from self-assembling monolayers is described. The arrays have particular utility for the screening of peptides ligands that can foster the growth of cells in culture. This technique has been used to identify peptide ligands that foster the growth of human stem cells, which otherwise require an extracellular matrix in order to grow in an undifferentiated state. This also makes possible an assay to identify other such peptides.
    Type: Application
    Filed: November 8, 2011
    Publication date: May 31, 2012
    Inventors: LAURA L. KIESSLING, Ratmir Derda, Brendan P. Orner, James A. Thomson
  • Defined surfaces of self-assembled monolayers and stem cells
    Patent number: 8062890
    Abstract: A method for the construction of arrays from self-assembling monolayers is described. The arrays have particular utility for the screening of peptides ligands that can foster the growth of cells in culture. This technique has been used to identify peptide ligands that foster the growth of human stem cells, which otherwise require an extracellular matrix in order to grow in an undifferentiated state. This also makes possible an assay to identify other such peptides.
    Type: Grant
    Filed: August 15, 2006
    Date of Patent: November 22, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Laura L. Kiessling, Ratmir Derda, Brendan P. Orner, James A. Thomson
  • Proteomimetic compounds and methods
    Patent number: 6858600
    Abstract: The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: February 22, 2005
    Assignee: Yale University
    Inventors: Andrew D. Hamilton, Justin Ernst, Brendan P. Orner
  • Proteomimetic compounds and methods
    Publication number: 20030008882
    Abstract: The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.
    Type: Application
    Filed: May 8, 2002
    Publication date: January 9, 2003
    Inventors: Andrew D. Hamilton, Justin Ernst, Brendan P. Orner