Patents by Inventor Bret C. Hassel

Bret C. Hassel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for preventing and treating cancer via modulating UBE1L, ISG215 and/or UBP43
    Patent number: 8697668
    Abstract: Compositions and methods of using compositions that induce UBE1L or a ubiquitin-like protein ISG15, or inhibit a deconjugase UBP43 to degrade oncogenic proteins and enhance apoptosis of cancer (neoplastic) or pre-cancerous (pre-neoplastic) cells are provided. Methods for the prevention or treatment of cancer via administration of these compositions are also provided.
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: April 15, 2014
    Assignee: Trustees of Dartmouth College
    Inventors: Ethan Dmitrovsky, Bret C. Hassel, Sutisak Kitareewan, Ian Pitha-Rowe
  • Compositions and Methods for Preventing and Treating Cancer via Modulating UBE1L, ISG215 and/or UBP43
    Publication number: 20130041016
    Abstract: Compositions and methods of using compositions that induce UBE1L or a ubiquitin-like protein ISG15, or inhibit a deconjugase UBP43 to degrade oncogenic proteins and enhance apoptosis of cancer (neoplastic) or pre-cancerous (pre-neoplastic) cells are provided. Methods for the prevention or treatment of cancer via administration of these compositions are also provided.
    Type: Application
    Filed: September 17, 2012
    Publication date: February 14, 2013
    Applicant: Trustees of Dartmouth College
    Inventors: Ethan Dmitrovsky, Bret C. Hassel, Sutisak Kitareewan, Ian Pitha-Rowe