Patents by Inventor Brian A. Mendelsohn

Brian A. Mendelsohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AURISTATIN-RELATED COMPOUNDS, CONJUGATED AURISTATIN-RELATED COMPOUNDS, AND METHODS OF USE THEREOF
    Publication number: 20230071763
    Abstract: The invention relates generally to novel compounds of the auristatin family, to novel linkers for coupling a payload to another molecule, such a target-binding molecule, to novel linker-toxin molecules, and to novel antibody molecules that allow controlled, site-specific conjugation.
    Type: Application
    Filed: January 6, 2021
    Publication date: March 9, 2023
    Inventors: Siew Schleyer, Brian A. Mendelsohn, Pia Challita-Eid, Dowdy Jackson, Christopher Kemball
  • Auristatins having an aminobenzoic acid unit at the N terminus
    Patent number: 8288352
    Abstract: Auristatin-type peptides are disclosed which are highly cytotoxic, synthetically accessible, and can be conjugated to antibodies and other ligands.
    Type: Grant
    Filed: November 14, 2005
    Date of Patent: October 16, 2012
    Assignee: Seattle Genetics, Inc.
    Inventors: Svetlana O. Doronina, Brian A. Mendelsohn
  • Auristatins Having an Aminobenzoic Acid Unit at the N Terminus
    Publication number: 20080300192
    Abstract: Auristatin-type peptides are disclosed which are highly cytotoxic, synthetically accessible, and can be conjugated to antibodies and other ligands.
    Type: Application
    Filed: November 14, 2005
    Publication date: December 4, 2008
    Applicant: Seattle Genetics, Inc.
    Inventors: Svetlana o. Doronina, Brian A. Mendelsohn