Patents by Inventor Brian A. Whittle

Brian A. Whittle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10004684
    Abstract: The invention relates to pharmaceutical formulations for use in the administration of lipophilic medicaments via mucosal surfaces. In particular the invention provides pharmaceutical formulations for use in administration of a lipophilic medicament via a mucosal surface which upon hydration form an emulsion containing the lipophilic medicament which is capable of adhering to a mucosal surface and allowing controlled release of the medicament. The invention further provides pharmaceutical formulations which contain, as active ingredients, specific combinations of cannabinoids in pre-defined ratios.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: June 26, 2018
    Assignee: GW Pharma Limited
    Inventors: Brian Whittle, Geoffrey Guy
  • Patent number: 9034395
    Abstract: Processes for preparing extracts of natural products such as plant material, and for preparing purified extracts from crude extracts of natural products, by extraction with hot gas. Apparatus suitable for use in preparing extracts of natural products are also described.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: May 19, 2015
    Assignee: GW Pharma Limited
    Inventors: Brian Whittle, Geoffrey Guy, David Downs, David W. Pate
  • Publication number: 20120225136
    Abstract: The invention relates to the use of a cannabis plant extract or a cannabinoid as a pharmaceutically active agent in the inhibition of tumour cell migration.
    Type: Application
    Filed: April 5, 2012
    Publication date: September 6, 2012
    Applicant: GW Pharma Limited
    Inventors: Brian Whittle, Daniela Parolaro
  • Publication number: 20120059062
    Abstract: Cannabinoids, in particular CBD and CBDA and their acid derivatives are provided for use as an active pharmaceutical substance in the treatment of nausea, vomiting, emesis, motion sickness. In particular extracts of cannabis plants are presented which are rich in these substances and suitable for pharmaceutical use.
    Type: Application
    Filed: August 31, 2011
    Publication date: March 8, 2012
    Applicant: GW Pharma Limited
    Inventors: Brian Whittle, Farideh Afshin Javid
  • Patent number: 8034843
    Abstract: Cannabinoids, in particular CBD and CBDA and their acid derivatives are provided for use as an active pharmaceutical substance in the treatment of nausea, vomiting, emesis, motion sickness. In particular extracts of cannabis plants are presented which are rich in these substances and suitable for pharmaceutical use.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: October 11, 2011
    Assignee: GW Pharma Limited
    Inventors: Brian Whittle, Farideh Afshin Javid
  • Publication number: 20100196488
    Abstract: The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.
    Type: Application
    Filed: February 12, 2010
    Publication date: August 5, 2010
    Applicant: GW Pharma Limited
    Inventor: Brian Whittle
  • Publication number: 20100119606
    Abstract: Processes for preparing extracts of natural products such as plant material, and for preparing purified extracts from crude extracts of natural products, by extraction with hot gas. Apparatus suitable for use in preparing extracts of natural products are also described.
    Type: Application
    Filed: November 13, 2009
    Publication date: May 13, 2010
    Applicant: GW Pharma Limited
    Inventors: Brian Whittle, Geoffrey Guy, David Downs, David W. Pate
  • Patent number: 7709536
    Abstract: The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: May 4, 2010
    Assignee: GW Pharma Limited
    Inventor: Brian Whittle
  • Patent number: 7622140
    Abstract: Processes for preparing extracts of natural products such as plant material, and for preparing purified extracts from crude extracts of natural products, by extraction with hot gas. Apparatus suitable for use in preparing extracts of natural products are also described.
    Type: Grant
    Filed: May 7, 2002
    Date of Patent: November 24, 2009
    Assignee: GW Pharma Limited
    Inventors: Brian Whittle, Geoffrey Guy, David Downs, David Pate
  • Publication number: 20080262099
    Abstract: The invention relates to the use of a cannabis plant extract or a cannabinoid as a pharmaceutically active agent in the inhibition of tumour cell migration.
    Type: Application
    Filed: September 30, 2005
    Publication date: October 23, 2008
    Applicant: GW Pharma Limited
    Inventors: Brian Whittle, Daniela Parolaro
  • Publication number: 20080167483
    Abstract: The invention relates to the extraction of pharmaceutically active components from plant materials, and more particularly to the preparation of a botanical drug substance (BDS) for incorporation in to a medicament. It also relates to a BDS of given purity, for use in pharmaceutical formulations. In particular it relates to BDS comprising cannabinoids obtained by extraction from cannabis.
    Type: Application
    Filed: March 17, 2008
    Publication date: July 10, 2008
    Applicant: GW Pharma Limited
    Inventors: Brian A. Whittle, Colin A. Hill, Ian R. Flockhart, David V. Downs, Peter Gibson, Gary W. Wheatley
  • Patent number: 7368137
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: May 6, 2008
    Assignee: Phytopharm PLC
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Patent number: 7344736
    Abstract: The invention relates to the extraction of pharmaceutically active components from plant materials, and more particularly to the preparation of a botanical drug substance (BDS) for incorporation in to a medicament. It also relates to a BDS of given purity, for use in pharmaceutical formulations. In particular it relates to BDS comprising cannabinoids obtained by extraction from cannabis.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: March 18, 2008
    Assignee: GW Pharma Limited
    Inventors: Brian Whittle, Colin A. Hill, Ian R. Flockhart, David Victor Downs, Peter Gibson, Gary William Wheatley
  • Publication number: 20070281056
    Abstract: Premixes, flour enriched with same, mineral supplemented foodstuffs and methods of manufacture thereof. The present invention relates to a premix for addition to foodstuffs and more particularly farinaceous products and bread. Use of the premix in foodstuffs enables their nutritional and mineral content to be enhanced providing health benefits and more particularly improved bone health.
    Type: Application
    Filed: August 11, 2005
    Publication date: December 6, 2007
    Applicant: NUTRACEUTICALS LIMITED
    Inventors: Brian Whittle, Paul Hart
  • Publication number: 20070191290
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceuical compositions are also disclosed.
    Type: Application
    Filed: January 9, 2007
    Publication date: August 16, 2007
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Patent number: 7166308
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: January 23, 2007
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Publication number: 20060182817
    Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: July 17, 2004
    Publication date: August 17, 2006
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
  • Publication number: 20060157491
    Abstract: The present invention relates to novel formulations, dosage forms and modes of delivery for treating patients addicted to a group of drugs which can result in dependence and misuse. The most serious drugs of addiction are cocaine, diamorphine (heroin), morphine and the synthetic opioids.
    Type: Application
    Filed: July 6, 2004
    Publication date: July 20, 2006
    Inventors: Brian Whittle, Rajiv Dave
  • Patent number: 7025992
    Abstract: The invention relates to pharmaceutical formulations for use in the administration of lipophilic medicaments via mucosal surfaces. In particular the invention provides pharmaceutical formulations for use in administration of a lipophilic medicament via a mucosal surface which upon hydration form an emulsion containing the lipophilic medicament which is capable of adhering to a mucosal surface and allowing controlled release of the medicament. The invention further provides pharmaceutical formulations which contain, as active ingredients, specific combinations of cannabinoids in pre-defined ratios.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: April 11, 2006
    Assignee: GW Pharma Limited
    Inventors: Brian A. Whittle, Geoffrey W. Guy
  • Publication number: 20060068034
    Abstract: The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.
    Type: Application
    Filed: September 16, 2005
    Publication date: March 30, 2006
    Inventor: Brian Whittle